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The map label for this gene is xdhB [H]

Identifier: 73542758

GI number: 73542758

Start: 3384325

End: 3385209

Strand: Direct

Name: xdhB [H]

Synonym: Reut_A3074

Alternate gene names: 73542758

Gene position: 3384325-3385209 (Clockwise)

Preceding gene: 73542756

Following gene: 73542759

Centisome position: 88.91

GC content: 65.65

Gene sequence:

>885_bases
ATGAGAGCGTTTGAATACTTCGAGCCGGCCACGCTTGCCGATGCTTCGGCAATGCTGCACCGCGCCGGCGGCAAGGCCAC
CGTGCTGGCCGGCGGCACCGACCTGCTCGTGCAGATCAAGGAGTCGGTGCGCAAGCCCGAGCAGGTCATCAACATCAAGA
AGATCCCGGGCATGGACGTGCTTACGTTCGATCCCGTGAATGGCCTGCGCATCGGTGCGCTGGTCACTACGCGTCAACTC
GAAACCTGTGGCTTTGTGCAGCGGCACTACGCCGGGCTGGCGAAGGCGGTGACGGACTTCGCCTCGATCCAGGTGCGCCA
CCGCGCAACCGTGGTCGGCAATGTGTGCCGCGCGTCGCCGTCGGCCGATTCCATCGCGCCGCTGGTCGCGGATCGTGCAT
CGGTGCATTTGTATGGACTGTCGGGCTCGCGCGAGATGCGCGTGGAGGACTTCATCACCGACGTCGGCAAGACCGCGATC
GCACCGGACGAAATCGTGACTCGCATCACCGTGCCCGCACCGCGCGCGCATACCGGCAAGGTCTATCTCAAGCATGGCCG
GCGCGTGCAGATGGAACTGGCCACGGTTGGCGTAGCGGTATCGCTGACCATCGAAGAAGGCCGCTGTACAGATGCCAACA
TCGTGCTCGCCGCGGTGGGGCCCACGCCGGTACGCGCCGAACACGCCGAGGCACTGCTGCGCGACCGCCACCTCACCGAT
GCACTGATCCTGCAGGCCGCACATGCCGCCACACGCGACGCGCGCCCGATCAGCGACGTGCGTGCGAGCGAAGCCTATCG
CCGACAGATGGTCAGCGTGCTCACGCGCCGCGCGCTAGAGGAAGCCCACAAACGCGCTTTGGAGGCCACACCGTGCGAAA
GCTAA

Upstream 100 bases:

>100_bases
ATTAATAGGTTTCGAGGTCTTTACCGATGATGGCCCTCACACCATGATGGTTGCTAACGGATGGCCCCGCAGGCCGCCGA
AGCAATCCTCAGGAGAAGCG

Downstream 100 bases:

>100_bases
TCGAACTCGTCATCAACGGCGAACCGCGCGAGCTTGCGGTCGAGCCGCACGCCACGCTGCTGGACGCGCTGCGCAACGAC
GCCGGCCTGACTGGTACCAA

Product: molybdopterin dehydrogenase, FAD-binding:CO dehydrogenase flavoprotein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MRAFEYFEPATLADASAMLHRAGGKATVLAGGTDLLVQIKESVRKPEQVINIKKIPGMDVLTFDPVNGLRIGALVTTRQL
ETCGFVQRHYAGLAKAVTDFASIQVRHRATVVGNVCRASPSADSIAPLVADRASVHLYGLSGSREMRVEDFITDVGKTAI
APDEIVTRITVPAPRAHTGKVYLKHGRRVQMELATVGVAVSLTIEEGRCTDANIVLAAVGPTPVRAEHAEALLRDRHLTD
ALILQAAHAATRDARPISDVRASEAYRRQMVSVLTRRALEEAHKRALEATPCES

Sequences:

>Translated_294_residues
MRAFEYFEPATLADASAMLHRAGGKATVLAGGTDLLVQIKESVRKPEQVINIKKIPGMDVLTFDPVNGLRIGALVTTRQL
ETCGFVQRHYAGLAKAVTDFASIQVRHRATVVGNVCRASPSADSIAPLVADRASVHLYGLSGSREMRVEDFITDVGKTAI
APDEIVTRITVPAPRAHTGKVYLKHGRRVQMELATVGVAVSLTIEEGRCTDANIVLAAVGPTPVRAEHAEALLRDRHLTD
ALILQAAHAATRDARPISDVRASEAYRRQMVSVLTRRALEEAHKRALEATPCES
>Mature_294_residues
MRAFEYFEPATLADASAMLHRAGGKATVLAGGTDLLVQIKESVRKPEQVINIKKIPGMDVLTFDPVNGLRIGALVTTRQL
ETCGFVQRHYAGLAKAVTDFASIQVRHRATVVGNVCRASPSADSIAPLVADRASVHLYGLSGSREMRVEDFITDVGKTAI
APDEIVTRITVPAPRAHTGKVYLKHGRRVQMELATVGVAVSLTIEEGRCTDANIVLAAVGPTPVRAEHAEALLRDRHLTD
ALILQAAHAATRDARPISDVRASEAYRRQMVSVLTRRALEEAHKRALEATPCES

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=278, Percent_Identity=30.2158273381295, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786479, Length=284, Percent_Identity=28.5211267605634, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 31765; Mature: 31765

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFEYFEPATLADASAMLHRAGGKATVLAGGTDLLVQIKESVRKPEQVINIKKIPGMDV
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHHHHEEHCCCCCCEE
LTFDPVNGLRIGALVTTRQLETCGFVQRHYAGLAKAVTDFASIQVRHRATVVGNVCRASP
EEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SADSIAPLVADRASVHLYGLSGSREMRVEDFITDVGKTAIAPDEIVTRITVPAPRAHTGK
CCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCCCE
VYLKHGRRVQMELATVGVAVSLTIEEGRCTDANIVLAAVGPTPVRAEHAEALLRDRHLTD
EEEECCCEEEEEEEEEEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHH
ALILQAAHAATRDARPISDVRASEAYRRQMVSVLTRRALEEAHKRALEATPCES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRAFEYFEPATLADASAMLHRAGGKATVLAGGTDLLVQIKESVRKPEQVINIKKIPGMDV
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHHHHEEHCCCCCCEE
LTFDPVNGLRIGALVTTRQLETCGFVQRHYAGLAKAVTDFASIQVRHRATVVGNVCRASP
EEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SADSIAPLVADRASVHLYGLSGSREMRVEDFITDVGKTAIAPDEIVTRITVPAPRAHTGK
CCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCCCE
VYLKHGRRVQMELATVGVAVSLTIEEGRCTDANIVLAAVGPTPVRAEHAEALLRDRHLTD
EEEECCCEEEEEEEEEEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHH
ALILQAAHAATRDARPISDVRASEAYRRQMVSVLTRRALEEAHKRALEATPCES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]