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The map label for this gene is proW [C]

Identifier: 73542714

GI number: 73542714

Start: 3331143

End: 3332897

Strand: Direct

Name: proW [C]

Synonym: Reut_A3030

Alternate gene names: 73542714

Gene position: 3331143-3332897 (Clockwise)

Preceding gene: 73542712

Following gene: 73542715

Centisome position: 87.51

GC content: 66.27

Gene sequence:

>1755_bases
ATGATTCAGCCCCCAGCCAACGACAATCCGGCCACGCCAGCACCCGGCTATGACAGCCAGTTGCTGACCGCCCCGCCCAA
TCGCTTCGATTTCGCGCTGCTGCCGATCATCCTCGCGATCATCGTCATGGTGGCGTTCGCGGCACAGCAGATGAACGTGC
CGTTCGTGCCCGGCGAGCCGATGACCGTGCACCTGGACATCGCCTACCTGCCCTATTACCTGATGCGTACGAGCATTCGC
ATGCTCGCGGCGCTGGCGGCATCGCTGGTGTTCTCGCTCGCGTTCGCGGCGCTCGCGTCAAAAAACCGCACGGCCGAAAA
GGTGCTGGTGCCCGCGCTGGATATCCTGCAGTCGATCCCGGTGCTTGGCTTCCTGTCGATCACCGTGACCGGCTTTATCG
CGCTGTTCCCGGGCAACCTGATCGGCGTGGAATGCGCGGCGATCTTCGCGATCTTCACCTCGCAGGCCTGGAACATGGCG
TTCAGCCTGTACCAGTCGTTCCGCACGATTCCGGGCGACCTGATCGAGGCGGCGGCCATGTTCCGGCTGTCGCCATGGCA
GCGCTTCTGGCGCCTCGAAGTGCCGTTCGCCATGCCCGGGCTGCTGTGGAACATGATGATGTCGATGTCGGGCGGCTGGT
TCTTCGTGGTCGCGTCGGAGGCCATTTCGGTGTCGGGCCAGGACATCCGGCTGCCGGGCATCGGCTCCTATATCGCGCTG
GCCATCCAGCAGCAGAACCTGGCTGCGATCGGCTGGGCCATCCTGGCCATGCTGGTTGGCATCCTGGTGTATGACCAGCT
GCTGTTCCGCCCGCTGGTCGCGTGGGCCGACCGCTTCCGCTTCGAGACGCTGTCGCAGGACAACGAGCCCGAGTCGTGGC
TGCTCGACCTGCTGCGCCGCTCGGAATGGGTACGGGCGCTGCTCGCGCGCACTGCGGCGCTGGCTGAACGCACGCTCGCC
TGGGGCGCACGACGCCAGGCGCCTGCGACGGCCGAGCCCGATCCGCGCCGCGTGCAATGGCGCGAGCGCGCCGGTAACGC
GGTCATCCTGCTCGTGGCGCTGGCCGCGCTGAGCCGCGTGATGTACTTCGTGCACAGCGAAGTCGGCTGGCTCGAAGTCG
GCCATGTGCTGTGGCTCGGCACGCTGACGATGGTGCGCGTGATCGTGCTGATCGCGCTGGCCGCGGTGATCTGGGTGCCG
ATCGGCATCCGCATCGGCCTGAATCCGTCGGTGGCGCGCATCGCCCAGCCCGTGGCGCAGTTCCTGGCGGCCTTCCCGGC
GAACCTGATGTTCCCGCTGGTCGTCATGCTGATTGTGCGCTTCGGCCTGAACCCGGAAATCTGGCTGAGCCCGTTGCTGA
TCTTTGGCACGCAGTGGTACATCCTGTTCAATGTGGTGGCTGGCGCCTCGGGCATTCCGACCGAGCTGAAGCTGGCCGCC
CGCAATTTCGGCCTGCGCGGCTGGCTGCTGTGGAAGCGTTTCCTCATTCCCGCGGTGTTCCCGAGCCTGCTGACCGGGCT
GGTGACGGCCGCGGGCGGTTCGTGGAATGCCAGCATCGTGGCCGAATACGTGACGTGGGGCGACCGCACGCTGGTGGCGA
CGGGCCTTGGCAGCTATATCGCCGAGACGACCGCACGCGGCGATTTCCCGCGCATTGCGCTCGGCATCGGCGTCATGGCG
CTGTTCGTAGTCGGCTTCAACCGGCTGCTGTGGAACCGCCTGTATCAACTCGCGCAGGAGCGCACCCGCTTGTAA

Upstream 100 bases:

>100_bases
CGTGATGCCGGCGGCACCCACACCGCCTGTCGGGCCTGATCCACAGGCCGCCCGTTCGCCACCAGCATCCGCAAGCTGGT
CGCCCAGTCCACCAAGCGCC

Downstream 100 bases:

>100_bases
GGTAACGATGGCAGAAAACCTGAACCACGCCGTCACGGCGCCGGCCGTGATCGAGCTGCGCGGTGTATCGAAGATCTTCC
GCACGGCTAACAAGAGCGAC

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease; ABC Transporter Membrane Protein; ABC Transporter Nitrate Permease; ABC Transporter; ABC Anion Transporter; ABC-Type Anion Transport System Permease Component; Anion Transporter Permease Protein; Nitrate ABC Transporter Permease; ABC Transporter Inner Membrane Subunit; ABC Transporter Transmembrane Permease Protein; ABC-Type Anion Transport System; ABC-Type Nitrate Transport Permease; ABC Transport System Permease Protein; Transmembrane ABC Transporter Protein; Nitrate Transport System Permease Protein; Nitrate ABC Transporter Permease Protein; Anion ABC Transporter Permease; Taurine ABC Transporter Permease Protein; Sugar ABC Transporter; Sugar ABC Transporter 1 Permease Protein; Sulfonate Transport Permease Protein; Nitrate Transport System Permease

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MIQPPANDNPATPAPGYDSQLLTAPPNRFDFALLPIILAIIVMVAFAAQQMNVPFVPGEPMTVHLDIAYLPYYLMRTSIR
MLAALAASLVFSLAFAALASKNRTAEKVLVPALDILQSIPVLGFLSITVTGFIALFPGNLIGVECAAIFAIFTSQAWNMA
FSLYQSFRTIPGDLIEAAAMFRLSPWQRFWRLEVPFAMPGLLWNMMMSMSGGWFFVVASEAISVSGQDIRLPGIGSYIAL
AIQQQNLAAIGWAILAMLVGILVYDQLLFRPLVAWADRFRFETLSQDNEPESWLLDLLRRSEWVRALLARTAALAERTLA
WGARRQAPATAEPDPRRVQWRERAGNAVILLVALAALSRVMYFVHSEVGWLEVGHVLWLGTLTMVRVIVLIALAAVIWVP
IGIRIGLNPSVARIAQPVAQFLAAFPANLMFPLVVMLIVRFGLNPEIWLSPLLIFGTQWYILFNVVAGASGIPTELKLAA
RNFGLRGWLLWKRFLIPAVFPSLLTGLVTAAGGSWNASIVAEYVTWGDRTLVATGLGSYIAETTARGDFPRIALGIGVMA
LFVVGFNRLLWNRLYQLAQERTRL

Sequences:

>Translated_584_residues
MIQPPANDNPATPAPGYDSQLLTAPPNRFDFALLPIILAIIVMVAFAAQQMNVPFVPGEPMTVHLDIAYLPYYLMRTSIR
MLAALAASLVFSLAFAALASKNRTAEKVLVPALDILQSIPVLGFLSITVTGFIALFPGNLIGVECAAIFAIFTSQAWNMA
FSLYQSFRTIPGDLIEAAAMFRLSPWQRFWRLEVPFAMPGLLWNMMMSMSGGWFFVVASEAISVSGQDIRLPGIGSYIAL
AIQQQNLAAIGWAILAMLVGILVYDQLLFRPLVAWADRFRFETLSQDNEPESWLLDLLRRSEWVRALLARTAALAERTLA
WGARRQAPATAEPDPRRVQWRERAGNAVILLVALAALSRVMYFVHSEVGWLEVGHVLWLGTLTMVRVIVLIALAAVIWVP
IGIRIGLNPSVARIAQPVAQFLAAFPANLMFPLVVMLIVRFGLNPEIWLSPLLIFGTQWYILFNVVAGASGIPTELKLAA
RNFGLRGWLLWKRFLIPAVFPSLLTGLVTAAGGSWNASIVAEYVTWGDRTLVATGLGSYIAETTARGDFPRIALGIGVMA
LFVVGFNRLLWNRLYQLAQERTRL
>Mature_584_residues
MIQPPANDNPATPAPGYDSQLLTAPPNRFDFALLPIILAIIVMVAFAAQQMNVPFVPGEPMTVHLDIAYLPYYLMRTSIR
MLAALAASLVFSLAFAALASKNRTAEKVLVPALDILQSIPVLGFLSITVTGFIALFPGNLIGVECAAIFAIFTSQAWNMA
FSLYQSFRTIPGDLIEAAAMFRLSPWQRFWRLEVPFAMPGLLWNMMMSMSGGWFFVVASEAISVSGQDIRLPGIGSYIAL
AIQQQNLAAIGWAILAMLVGILVYDQLLFRPLVAWADRFRFETLSQDNEPESWLLDLLRRSEWVRALLARTAALAERTLA
WGARRQAPATAEPDPRRVQWRERAGNAVILLVALAALSRVMYFVHSEVGWLEVGHVLWLGTLTMVRVIVLIALAAVIWVP
IGIRIGLNPSVARIAQPVAQFLAAFPANLMFPLVVMLIVRFGLNPEIWLSPLLIFGTQWYILFNVVAGASGIPTELKLAA
RNFGLRGWLLWKRFLIPAVFPSLLTGLVTAAGGSWNASIVAEYVTWGDRTLVATGLGSYIAETTARGDFPRIALGIGVMA
LFVVGFNRLLWNRLYQLAQERTRL

Specific function: Involved In A Multicomponent Binding-Protein-Dependent Transport System For Glycine Betaine/L-Proline. [C]

COG id: COG4986

COG function: function code P; ABC-type anion transport system, duplicated permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64422; Mature: 64422

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQPPANDNPATPAPGYDSQLLTAPPNRFDFALLPIILAIIVMVAFAAQQMNVPFVPGEP
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MTVHLDIAYLPYYLMRTSIRMLAALAASLVFSLAFAALASKNRTAEKVLVPALDILQSIP
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
VLGFLSITVTGFIALFPGNLIGVECAAIFAIFTSQAWNMAFSLYQSFRTIPGDLIEAAAM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRLSPWQRFWRLEVPFAMPGLLWNMMMSMSGGWFFVVASEAISVSGQDIRLPGIGSYIAL
HHCCHHHHHHEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCEEECCCCCHHHHH
AIQQQNLAAIGWAILAMLVGILVYDQLLFRPLVAWADRFRFETLSQDNEPESWLLDLLRR
EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SEWVRALLARTAALAERTLAWGARRQAPATAEPDPRRVQWRERAGNAVILLVALAALSRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHH
MYFVHSEVGWLEVGHVLWLGTLTMVRVIVLIALAAVIWVPIGIRIGLNPSVARIAQPVAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHH
FLAAFPANLMFPLVVMLIVRFGLNPEIWLSPLLIFGTQWYILFNVVAGASGIPTELKLAA
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHH
RNFGLRGWLLWKRFLIPAVFPSLLTGLVTAAGGSWNASIVAEYVTWGDRTLVATGLGSYI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEHHHHHHHH
AETTARGDFPRIALGIGVMALFVVGFNRLLWNRLYQLAQERTRL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQPPANDNPATPAPGYDSQLLTAPPNRFDFALLPIILAIIVMVAFAAQQMNVPFVPGEP
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MTVHLDIAYLPYYLMRTSIRMLAALAASLVFSLAFAALASKNRTAEKVLVPALDILQSIP
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
VLGFLSITVTGFIALFPGNLIGVECAAIFAIFTSQAWNMAFSLYQSFRTIPGDLIEAAAM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FRLSPWQRFWRLEVPFAMPGLLWNMMMSMSGGWFFVVASEAISVSGQDIRLPGIGSYIAL
HHCCHHHHHHEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCEEECCCCCHHHHH
AIQQQNLAAIGWAILAMLVGILVYDQLLFRPLVAWADRFRFETLSQDNEPESWLLDLLRR
EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SEWVRALLARTAALAERTLAWGARRQAPATAEPDPRRVQWRERAGNAVILLVALAALSRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHH
MYFVHSEVGWLEVGHVLWLGTLTMVRVIVLIALAAVIWVPIGIRIGLNPSVARIAQPVAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHH
FLAAFPANLMFPLVVMLIVRFGLNPEIWLSPLLIFGTQWYILFNVVAGASGIPTELKLAA
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHH
RNFGLRGWLLWKRFLIPAVFPSLLTGLVTAAGGSWNASIVAEYVTWGDRTLVATGLGSYI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEHHHHHHHH
AETTARGDFPRIALGIGVMALFVVGFNRLLWNRLYQLAQERTRL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA