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The map label for this gene is pyc [H]

Identifier: 73542681

GI number: 73542681

Start: 3288739

End: 3292077

Strand: Direct

Name: pyc [H]

Synonym: Reut_A2997

Alternate gene names: 73542681

Gene position: 3288739-3292077 (Clockwise)

Preceding gene: 73542680

Following gene: 73542682

Centisome position: 86.4

GC content: 69.63

Gene sequence:

>3339_bases
ATGCTGGGGCGGGTGCCCCATGCCTCACCGCTATCCGACATGAATCCGCCGAAGCTCCTGATCGCCAACCGCGGCGAAAT
CGCCATCCGCATCGCCCGCGCGGCAGCGGCCCTGGACATGCCGAGCGTGGCCATCCACAGCGAGGACGACCGCGACGCGC
TGCACGTGCGCAAGGCCGATGATGCCGTGGCGCTGCCCGGCAGCGGTCCGCGCGCTTATCTCGATATCGAACAGGTGGTT
GCCGCCGCGCGGCGCGCCGGCTGCCAGCTAGTTCATCCCGGCTATGGGTTCCTGTCCGAGAACGCGGACTTCGCGCAGGC
CTGTCTGGACGCGGGTCTGATCTTCGTCGGTCCGGCGCCCGATGTGCTGCGGCTCTTCGGCGACAAGGCGCGGGCGCGCG
CACTGGCCCGCGAACATGGCGTGCCAGTGGTGCCGGGAACGACCGGGCCCACCACGCTGGCCGAAGCACATGCCTTCTTT
GCCGACTTGCCGAACGGTACCGGCATGATGATCAAGGCGCTGGCCGGCGGCGGCGGACGCGGCATGCGTGCAGTCCATGA
TGTGGCGCAGATCGACGAAGCATGGACACGTTGCGCGTCGGAAGCGACGGCGGCATTCGGCAACGGCGCGGTCTATGTCG
AACAGATCGTCACGGCGCCGCGCCACATCGAAATTCAGGTGGTCGCGGACACCAATGGGCAAGTCGTCACGCTCGGCGAA
CGCGAGTGCAGCCTGCAACGCCGCCACCAGAAGCTCGTGGAAGTCGCGCCCAGCCCCGCGCTCGACGATGCGACGCGCGC
GCGCCTCGCCGAGGCTGCCGCCACGCTGGCACGCGCGGCCGCGTACCGGGGCATCGGCACGTTTGAATTCCTTGTGCAGG
AACGCGACGGCCAGCCGCCCGCGTTCTGGTTCATGGAAGCCAACCCGCGCCTGCAGGTCGAACATACCGTGACCGAGATG
GTCACCGGCGTGGATCTCGTGCAAACCCAACTCGCCATTGCGATGGGCGCAGATCTCGCGCAACTGAGTATGGCACGCGC
GCCGGTACCGCGCGGCGTTGCCGTGCAGCTGCGCATCAATGCCGAACATCTCGACGGACAGGGCAACCTGCGCCCGGCCG
CGGGCACGCTCACCGCGTTCGAGGCGCCGAGCGGCCCCGGCGTGCGGGTCGATAGCGCGGGCTACGCGGGCATGGCAGCC
AACCCGCGCTTCGACTCGCTGCTCGCAAAGCTGATCGTGCACGAACCCAGCGGCAACTACGCACGTGCGCTGGGTCTGGC
GTACCGCGCGCTGTGCAAGTTCCGCATCGAGGGCATCAACACCAACCGGCGCCTGCTGCAGGACTTGCTGCAACAGGACG
CCGTGCAGCGCAACGCGGTCCACACGCAATACCTTGACCATGCATTGCCTGCGCTCGCCGCAGCCGATAGCGATCATCCT
GCGCTGCATGCCACCGCAACCGCGATCCCGGAGCAGCACCCCGACGACGAGGATGGCCTGCCCACCGATGCGTTCGCCGT
GCAGGCGCCGATGGACGGCGCGCTGGCCGCACTCCATGTGAAGCCGGGCGACACCGTGCGCCGTGGCCAGCCGCTAGCCG
TCATCGAAGCGATGAAGATGGAGCACCCGGTCGAGGCACCAGCCGCCGGCACCGTGCTGGCCGTGCGGACGGAGGCCGGC
GCCACCGTACGTGCCGGCGCCACGCTGGTGCTGATCGAAGCCGGCGACGACACCGGCCATGCCGAGCAGGCCTGCGCCGC
CGCTGATCTCGAGCATATCCGCGCCGACCTGCGCGAAGCGCTCGAGCGCCACGCACTCGGCCACGATGCCGCGCGCGACG
CTGCCGTGGCAAAACGCCACGCACAGGGCGGCCGTACCGCGCGCGAGAACATCGCGCAACTATGCGACGCCGACTCCTTC
ATCGAATACGGCGCGCTGGCCATCGCGGCCCAGCGCCAGCGCCGCACGGAAGACGACCTGATCCGCTCGACGCCGGCCGA
TGGCATCGTCACCGGCATCGGCACCGTGAATGCGGAGCAGCTTCCCGATGCTGACGCGCGTTGCATGGTCCTCGCCTACG
ACTACACGGTGCTGGCCGGCACGCAGGGCTACTACGGCCACAAGAAGCTGGACCGCATGCTCGCCCTGGCGCGGCAGTGG
CGACTGCCGGTGGTGCTGTTCGCCGAAGGTGGCGGCGGCCGCCCCGGCGACACCGACATGCCGGTAGTGGCTGGACTCGA
CTGCACCTCGTTCATCCAGTTCGCGCGGCTTTCCGGCCAAGTGCCGCTGGTCGGAATCGTGCACGGGCGCTGCTTCGCCG
GCAATGCGGCGCTGCTCGGCTGCGCCGACGTGATCATCGCCACGCGTAGCGCGACCATCGGCATGGGCGGCCCGGCCATG
ATCGAGGGCGGCGGCCTCGGCGTGTACGCACCCGAGGAAGTCGGCCCGGTCGGCGTGCAGGCGCCCAATGGCGTCATCGA
TGTCGTCGTCGACGACGAGCAGGCCGCTGTCGACACCGCGCGCCGCTACCTGGCCTACTTCCAGGGCGATGCCCCCGGCT
GGCGGGGCGAAGACCCACGCCATCTGCGCCATGCGATTCCCGAGAACCGCCTGCGCAGCTACGACATGCGTGCCGTCATC
CACGCGCTGGCGGACACAGATTCCGTGCTCGAACTGCGCGCTGCGTTCGGCACCGGCATCATCACCGCGCTGATCCGCAT
CGAAGGCCGTGCGTTCGGCTGCATCGCCAACAACCCGCGCCACCTCGGCGGCGCGATCGACAGCGCCGCCGGGGACAAGG
CCGCACGCTTCATGCAGCTGTGCGATGCGCACGGCCTGCCGATCCTGTCGCTGTGCGACACACCGGGCTTCATGGTCGGC
CCGCAGGCCGAGAAAAGCGCCACGGTGCGCCACGTCTCGCGCCTGTTCGTGGTGGCCGGCGCGCTGCGCGTGCCGTTCTT
CACAGTTGTGCTGCGCAAGGGCTACGGGCTCGGCGCGCAAGCGATGGCCGGCGGCAGCTTTGCCGCGCCGTTCTTCACGG
CAGCGTGGCCAAGCGGCGAATTTGGCGCCATGGGGCTGGAGGGTTCGATCCGGCTCGGCTTCCGCAAGGAACTGGAAGCC
GTGGCCGACCCCGACGAGCGCGAGGCGCTGTTCGCGCGCATGGTCGATGCCGCGTACCAACGCGGCCGCGCACTGAACAT
GGCGAGCCACCTCGAGATCGACGCCGTGATCGACCCTGCCGACACGCGCCGCTGGCTGTTGCGCGGCCTCGCCTCGGTGC
CGCCCCGCAGCCTCGGGCGGCGCACTGGCGAGGACCGCCGCTTCATCGACACCTGGTAA

Upstream 100 bases:

>100_bases
CCGCTGACGGCGACCGGCAAGGTGCGCAAGCAGGACCTGGTGCCGATGGCCGACGCACTGCGCTGACGCTGTATCCCCTC
TGCCTGCCCCACGCATTTCG

Downstream 100 bases:

>100_bases
TAACGCGCCGGGAACACGGCGCCACCCGGATTCTTCATCGACACAGGAGGAGACACCTGATGCAGTCCACCCCGTCAACG
CACAGATCAACCGGCGCGCG

Product: pyruvate carboxylase., propionyl-CoA carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1112; Mature: 1112

Protein sequence:

>1112_residues
MLGRVPHASPLSDMNPPKLLIANRGEIAIRIARAAAALDMPSVAIHSEDDRDALHVRKADDAVALPGSGPRAYLDIEQVV
AAARRAGCQLVHPGYGFLSENADFAQACLDAGLIFVGPAPDVLRLFGDKARARALAREHGVPVVPGTTGPTTLAEAHAFF
ADLPNGTGMMIKALAGGGGRGMRAVHDVAQIDEAWTRCASEATAAFGNGAVYVEQIVTAPRHIEIQVVADTNGQVVTLGE
RECSLQRRHQKLVEVAPSPALDDATRARLAEAAATLARAAAYRGIGTFEFLVQERDGQPPAFWFMEANPRLQVEHTVTEM
VTGVDLVQTQLAIAMGADLAQLSMARAPVPRGVAVQLRINAEHLDGQGNLRPAAGTLTAFEAPSGPGVRVDSAGYAGMAA
NPRFDSLLAKLIVHEPSGNYARALGLAYRALCKFRIEGINTNRRLLQDLLQQDAVQRNAVHTQYLDHALPALAAADSDHP
ALHATATAIPEQHPDDEDGLPTDAFAVQAPMDGALAALHVKPGDTVRRGQPLAVIEAMKMEHPVEAPAAGTVLAVRTEAG
ATVRAGATLVLIEAGDDTGHAEQACAAADLEHIRADLREALERHALGHDAARDAAVAKRHAQGGRTARENIAQLCDADSF
IEYGALAIAAQRQRRTEDDLIRSTPADGIVTGIGTVNAEQLPDADARCMVLAYDYTVLAGTQGYYGHKKLDRMLALARQW
RLPVVLFAEGGGGRPGDTDMPVVAGLDCTSFIQFARLSGQVPLVGIVHGRCFAGNAALLGCADVIIATRSATIGMGGPAM
IEGGGLGVYAPEEVGPVGVQAPNGVIDVVVDDEQAAVDTARRYLAYFQGDAPGWRGEDPRHLRHAIPENRLRSYDMRAVI
HALADTDSVLELRAAFGTGIITALIRIEGRAFGCIANNPRHLGGAIDSAAGDKAARFMQLCDAHGLPILSLCDTPGFMVG
PQAEKSATVRHVSRLFVVAGALRVPFFTVVLRKGYGLGAQAMAGGSFAAPFFTAAWPSGEFGAMGLEGSIRLGFRKELEA
VADPDEREALFARMVDAAYQRGRALNMASHLEIDAVIDPADTRRWLLRGLASVPPRSLGRRTGEDRRFIDTW

Sequences:

>Translated_1112_residues
MLGRVPHASPLSDMNPPKLLIANRGEIAIRIARAAAALDMPSVAIHSEDDRDALHVRKADDAVALPGSGPRAYLDIEQVV
AAARRAGCQLVHPGYGFLSENADFAQACLDAGLIFVGPAPDVLRLFGDKARARALAREHGVPVVPGTTGPTTLAEAHAFF
ADLPNGTGMMIKALAGGGGRGMRAVHDVAQIDEAWTRCASEATAAFGNGAVYVEQIVTAPRHIEIQVVADTNGQVVTLGE
RECSLQRRHQKLVEVAPSPALDDATRARLAEAAATLARAAAYRGIGTFEFLVQERDGQPPAFWFMEANPRLQVEHTVTEM
VTGVDLVQTQLAIAMGADLAQLSMARAPVPRGVAVQLRINAEHLDGQGNLRPAAGTLTAFEAPSGPGVRVDSAGYAGMAA
NPRFDSLLAKLIVHEPSGNYARALGLAYRALCKFRIEGINTNRRLLQDLLQQDAVQRNAVHTQYLDHALPALAAADSDHP
ALHATATAIPEQHPDDEDGLPTDAFAVQAPMDGALAALHVKPGDTVRRGQPLAVIEAMKMEHPVEAPAAGTVLAVRTEAG
ATVRAGATLVLIEAGDDTGHAEQACAAADLEHIRADLREALERHALGHDAARDAAVAKRHAQGGRTARENIAQLCDADSF
IEYGALAIAAQRQRRTEDDLIRSTPADGIVTGIGTVNAEQLPDADARCMVLAYDYTVLAGTQGYYGHKKLDRMLALARQW
RLPVVLFAEGGGGRPGDTDMPVVAGLDCTSFIQFARLSGQVPLVGIVHGRCFAGNAALLGCADVIIATRSATIGMGGPAM
IEGGGLGVYAPEEVGPVGVQAPNGVIDVVVDDEQAAVDTARRYLAYFQGDAPGWRGEDPRHLRHAIPENRLRSYDMRAVI
HALADTDSVLELRAAFGTGIITALIRIEGRAFGCIANNPRHLGGAIDSAAGDKAARFMQLCDAHGLPILSLCDTPGFMVG
PQAEKSATVRHVSRLFVVAGALRVPFFTVVLRKGYGLGAQAMAGGSFAAPFFTAAWPSGEFGAMGLEGSIRLGFRKELEA
VADPDEREALFARMVDAAYQRGRALNMASHLEIDAVIDPADTRRWLLRGLASVPPRSLGRRTGEDRRFIDTW
>Mature_1112_residues
MLGRVPHASPLSDMNPPKLLIANRGEIAIRIARAAAALDMPSVAIHSEDDRDALHVRKADDAVALPGSGPRAYLDIEQVV
AAARRAGCQLVHPGYGFLSENADFAQACLDAGLIFVGPAPDVLRLFGDKARARALAREHGVPVVPGTTGPTTLAEAHAFF
ADLPNGTGMMIKALAGGGGRGMRAVHDVAQIDEAWTRCASEATAAFGNGAVYVEQIVTAPRHIEIQVVADTNGQVVTLGE
RECSLQRRHQKLVEVAPSPALDDATRARLAEAAATLARAAAYRGIGTFEFLVQERDGQPPAFWFMEANPRLQVEHTVTEM
VTGVDLVQTQLAIAMGADLAQLSMARAPVPRGVAVQLRINAEHLDGQGNLRPAAGTLTAFEAPSGPGVRVDSAGYAGMAA
NPRFDSLLAKLIVHEPSGNYARALGLAYRALCKFRIEGINTNRRLLQDLLQQDAVQRNAVHTQYLDHALPALAAADSDHP
ALHATATAIPEQHPDDEDGLPTDAFAVQAPMDGALAALHVKPGDTVRRGQPLAVIEAMKMEHPVEAPAAGTVLAVRTEAG
ATVRAGATLVLIEAGDDTGHAEQACAAADLEHIRADLREALERHALGHDAARDAAVAKRHAQGGRTARENIAQLCDADSF
IEYGALAIAAQRQRRTEDDLIRSTPADGIVTGIGTVNAEQLPDADARCMVLAYDYTVLAGTQGYYGHKKLDRMLALARQW
RLPVVLFAEGGGGRPGDTDMPVVAGLDCTSFIQFARLSGQVPLVGIVHGRCFAGNAALLGCADVIIATRSATIGMGGPAM
IEGGGLGVYAPEEVGPVGVQAPNGVIDVVVDDEQAAVDTARRYLAYFQGDAPGWRGEDPRHLRHAIPENRLRSYDMRAVI
HALADTDSVLELRAAFGTGIITALIRIEGRAFGCIANNPRHLGGAIDSAAGDKAARFMQLCDAHGLPILSLCDTPGFMVG
PQAEKSATVRHVSRLFVVAGALRVPFFTVVLRKGYGLGAQAMAGGSFAAPFFTAAWPSGEFGAMGLEGSIRLGFRKELEA
VADPDEREALFARMVDAAYQRGRALNMASHLEIDAVIDPADTRRWLLRGLASVPPRSLGRRTGEDRRFIDTW

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=454, Percent_Identity=45.8149779735683, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI106049295, Length=454, Percent_Identity=45.8149779735683, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI106049292, Length=454, Percent_Identity=45.8149779735683, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI116805327, Length=456, Percent_Identity=39.2543859649123, Blast_Score=310, Evalue=6e-84,
Organism=Homo sapiens, GI65506442, Length=456, Percent_Identity=38.5964912280702, Blast_Score=284, Evalue=3e-76,
Organism=Homo sapiens, GI189095269, Length=456, Percent_Identity=38.5964912280702, Blast_Score=284, Evalue=4e-76,
Organism=Homo sapiens, GI295821183, Length=456, Percent_Identity=38.5964912280702, Blast_Score=284, Evalue=4e-76,
Organism=Homo sapiens, GI38679977, Length=521, Percent_Identity=28.9827255278311, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI38679967, Length=521, Percent_Identity=28.9827255278311, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI38679974, Length=521, Percent_Identity=28.9827255278311, Blast_Score=186, Evalue=2e-46,
Organism=Homo sapiens, GI38679960, Length=521, Percent_Identity=28.9827255278311, Blast_Score=186, Evalue=2e-46,
Organism=Homo sapiens, GI38679971, Length=521, Percent_Identity=28.9827255278311, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI134142062, Length=517, Percent_Identity=29.2069632495164, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI119943100, Length=480, Percent_Identity=25.4166666666667, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI295821216, Length=494, Percent_Identity=25.3036437246964, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI11545863, Length=423, Percent_Identity=28.3687943262411, Blast_Score=130, Evalue=9e-30,
Organism=Escherichia coli, GI1789654, Length=456, Percent_Identity=43.421052631579, Blast_Score=319, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI17562816, Length=454, Percent_Identity=45.1541850220264, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71987519, Length=463, Percent_Identity=37.7969762419007, Blast_Score=291, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17567343, Length=464, Percent_Identity=38.3620689655172, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI25147359, Length=517, Percent_Identity=27.0793036750484, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25147362, Length=517, Percent_Identity=27.0793036750484, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17552936, Length=542, Percent_Identity=26.3837638376384, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71997163, Length=519, Percent_Identity=26.3969171483622, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71997168, Length=519, Percent_Identity=26.3969171483622, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133931226, Length=462, Percent_Identity=27.0562770562771, Blast_Score=151, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319695, Length=456, Percent_Identity=42.3245614035088, Blast_Score=323, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6321376, Length=456, Percent_Identity=42.7631578947368, Blast_Score=312, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6319685, Length=473, Percent_Identity=37.4207188160677, Blast_Score=305, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6324343, Length=532, Percent_Identity=27.8195488721804, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323863, Length=474, Percent_Identity=28.9029535864979, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281363050, Length=453, Percent_Identity=45.2538631346578, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652224, Length=453, Percent_Identity=45.2538631346578, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652222, Length=453, Percent_Identity=45.2538631346578, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652220, Length=453, Percent_Identity=45.2538631346578, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652218, Length=453, Percent_Identity=45.2538631346578, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652212, Length=453, Percent_Identity=45.2538631346578, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652210, Length=453, Percent_Identity=45.2538631346578, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652214, Length=453, Percent_Identity=45.2538631346578, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI19921944, Length=453, Percent_Identity=45.2538631346578, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24652216, Length=453, Percent_Identity=45.2538631346578, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24651757, Length=471, Percent_Identity=39.0658174097665, Blast_Score=301, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24651759, Length=423, Percent_Identity=38.7706855791962, Blast_Score=268, Evalue=2e-71,
Organism=Drosophila melanogaster, GI161076409, Length=504, Percent_Identity=28.7698412698413, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24586458, Length=504, Percent_Identity=28.7698412698413, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161076407, Length=504, Percent_Identity=28.7698412698413, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586460, Length=504, Percent_Identity=28.7698412698413, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586065, Length=545, Percent_Identity=26.7889908256881, Blast_Score=152, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 117866; Mature: 117866

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRVPHASPLSDMNPPKLLIANRGEIAIRIARAAAALDMPSVAIHSEDDRDALHVRKAD
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCCCCCEEEECCCCCCCEEEEECC
DAVALPGSGPRAYLDIEQVVAAARRAGCQLVHPGYGFLSENADFAQACLDAGLIFVGPAP
CCEECCCCCCEEEEEHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCEEEECCCH
DVLRLFGDKARARALAREHGVPVVPGTTGPTTLAEAHAFFADLPNGTGMMIKALAGGGGR
HHHHHHCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
GMRAVHDVAQIDEAWTRCASEATAAFGNGAVYVEQIVTAPRHIEIQVVADTNGQVVTLGE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEEEEEEECCCCCEEEECC
RECSLQRRHQKLVEVAPSPALDDATRARLAEAAATLARAAAYRGIGTFEFLVQERDGQPP
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
AFWFMEANPRLQVEHTVTEMVTGVDLVQTQLAIAMGADLAQLSMARAPVPRGVAVQLRIN
EEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEE
AEHLDGQGNLRPAAGTLTAFEAPSGPGVRVDSAGYAGMAANPRFDSLLAKLIVHEPSGNY
HHHCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHEECCCCCH
ARALGLAYRALCKFRIEGINTNRRLLQDLLQQDAVQRNAVHTQYLDHALPALAAADSDHP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ALHATATAIPEQHPDDEDGLPTDAFAVQAPMDGALAALHVKPGDTVRRGQPLAVIEAMKM
CEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
EHPVEAPAAGTVLAVRTEAGATVRAGATLVLIEAGDDTGHAEQACAAADLEHIRADLREA
CCCCCCCCCCCEEEEEECCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LERHALGHDAARDAAVAKRHAQGGRTARENIAQLCDADSFIEYGALAIAAQRQRRTEDDL
HHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
IRSTPADGIVTGIGTVNAEQLPDADARCMVLAYDYTVLAGTQGYYGHKKLDRMLALARQW
HHCCCCCCEEECCCCCCHHHCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHC
RLPVVLFAEGGGGRPGDTDMPVVAGLDCTSFIQFARLSGQVPLVGIVHGRCFAGNAALLG
CCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECEEEECCCHHHH
CADVIIATRSATIGMGGPAMIEGGGLGVYAPEEVGPVGVQAPNGVIDVVVDDEQAAVDTA
HHHHHEEECCCEECCCCCCEEECCCEEEECCHHCCCCCCCCCCCEEEEEECCCHHHHHHH
RRYLAYFQGDAPGWRGEDPRHLRHAIPENRLRSYDMRAVIHALADTDSVLELRAAFGTGI
HHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ITALIRIEGRAFGCIANNPRHLGGAIDSAAGDKAARFMQLCDAHGLPILSLCDTPGFMVG
HHHHHEECCCEEEEECCCCHHHCCCHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEC
PQAEKSATVRHVSRLFVVAGALRVPFFTVVLRKGYGLGAQAMAGGSFAAPFFTAAWPSGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEECCCCCC
FGAMGLEGSIRLGFRKELEAVADPDEREALFARMVDAAYQRGRALNMASHLEIDAVIDPA
CCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEECHHHHCEEEEEECCC
DTRRWLLRGLASVPPRSLGRRTGEDRRFIDTW
HHHHHHHHHHHCCCCHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MLGRVPHASPLSDMNPPKLLIANRGEIAIRIARAAAALDMPSVAIHSEDDRDALHVRKAD
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCCCCCEEEECCCCCCCEEEEECC
DAVALPGSGPRAYLDIEQVVAAARRAGCQLVHPGYGFLSENADFAQACLDAGLIFVGPAP
CCEECCCCCCEEEEEHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCEEEECCCH
DVLRLFGDKARARALAREHGVPVVPGTTGPTTLAEAHAFFADLPNGTGMMIKALAGGGGR
HHHHHHCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
GMRAVHDVAQIDEAWTRCASEATAAFGNGAVYVEQIVTAPRHIEIQVVADTNGQVVTLGE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEEEEEEECCCCCEEEECC
RECSLQRRHQKLVEVAPSPALDDATRARLAEAAATLARAAAYRGIGTFEFLVQERDGQPP
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
AFWFMEANPRLQVEHTVTEMVTGVDLVQTQLAIAMGADLAQLSMARAPVPRGVAVQLRIN
EEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEE
AEHLDGQGNLRPAAGTLTAFEAPSGPGVRVDSAGYAGMAANPRFDSLLAKLIVHEPSGNY
HHHCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHEECCCCCH
ARALGLAYRALCKFRIEGINTNRRLLQDLLQQDAVQRNAVHTQYLDHALPALAAADSDHP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ALHATATAIPEQHPDDEDGLPTDAFAVQAPMDGALAALHVKPGDTVRRGQPLAVIEAMKM
CEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
EHPVEAPAAGTVLAVRTEAGATVRAGATLVLIEAGDDTGHAEQACAAADLEHIRADLREA
CCCCCCCCCCCEEEEEECCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LERHALGHDAARDAAVAKRHAQGGRTARENIAQLCDADSFIEYGALAIAAQRQRRTEDDL
HHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
IRSTPADGIVTGIGTVNAEQLPDADARCMVLAYDYTVLAGTQGYYGHKKLDRMLALARQW
HHCCCCCCEEECCCCCCHHHCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHC
RLPVVLFAEGGGGRPGDTDMPVVAGLDCTSFIQFARLSGQVPLVGIVHGRCFAGNAALLG
CCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEEECEEEECCCHHHH
CADVIIATRSATIGMGGPAMIEGGGLGVYAPEEVGPVGVQAPNGVIDVVVDDEQAAVDTA
HHHHHEEECCCEECCCCCCEEECCCEEEECCHHCCCCCCCCCCCEEEEEECCCHHHHHHH
RRYLAYFQGDAPGWRGEDPRHLRHAIPENRLRSYDMRAVIHALADTDSVLELRAAFGTGI
HHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ITALIRIEGRAFGCIANNPRHLGGAIDSAAGDKAARFMQLCDAHGLPILSLCDTPGFMVG
HHHHHEECCCEEEEECCCCHHHCCCHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEC
PQAEKSATVRHVSRLFVVAGALRVPFFTVVLRKGYGLGAQAMAGGSFAAPFFTAAWPSGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEECCCCCC
FGAMGLEGSIRLGFRKELEAVADPDEREALFARMVDAAYQRGRALNMASHLEIDAVIDPA
CCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEECHHHHCEEEEEECCC
DTRRWLLRGLASVPPRSLGRRTGEDRRFIDTW
HHHHHHHHHHHCCCCHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]