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The map label for this gene is pabB [H]

Identifier: 73542468

GI number: 73542468

Start: 3050902

End: 3052689

Strand: Reverse

Name: pabB [H]

Synonym: Reut_A2783

Alternate gene names: 73542468

Gene position: 3052689-3050902 (Counterclockwise)

Preceding gene: 73542469

Following gene: 73542458

Centisome position: 80.2

GC content: 68.29

Gene sequence:

>1788_bases
ATGTCACGGCTCTACACCGGCCTCGTTCGCGAAGACCGGCTGCCCGCTGGCAGTGATGTCGCGCTGATCGATGCACTGCT
CGCCGAAGGCTGGCGCCAGGGCTGGCACGCGACGCTGTTCGCACCCTACGAATTCGGCGGCGCGCTGGTCGGCGCCCCGG
CGCACACCGACGACAGGTTGCCCTTCCACGATGGCGCCGTGCGCCTGCTCTGGTTCCGCGACATGCGGCGGCTCGACGGC
GATGCCGTGCGCGCCTGGCTGCCTGAACCCGATGCACAAGCGCCCGCCGGGCTCATGAATGTCGCCGCGGATACCCCGCG
CGAAGCCTTCGATACCGCCATTGCCCGCATCCATGCATGGATCGAAGCCGGCGATACCTACCAGGTCAATTTCACGCAGC
GGATCGCATTCTCGTCGTTTGGCGATCCGCGCGCGCTCTACGCCGCGTTGCGCGACGCGCAGCCGGTGCCCTATGGCGTG
CTGGCCTGCCTGCCCGGCGATGGCTGGGTACTGTCGCTGTCGCCCGAGCTTTTCGTGCAGCACGATGGAAGCGGCCGTCT
GCTCACGCGTCCGATGAAGGGCACTGCGCCGCTGTCCGGCGATCCCGGGCAAGACGCGCAAGCCGCCGCCGGCCTCGCCG
CCGATGCGAAGAATCGCGCCGAGAACGTGATGATCGTGGACCTGCTTCGCAACGACCTTGGACGCATTGCGCAACCGGGC
AGCGTGGAAGTGCCGGACCGCTTTGTTGTGCAGCCGTTCGGCGCCGTGCTGCAGATGACCTCGACCGTCAGGGCAACGGC
GCGCGCTGCCACGCGGTTCGGCGAACTCTTCGGGGCGCTGTTCCCGTGTGGCTCGATCACCGGCGCGCCCAAGCGGCGTA
CCATGCAAATCATTGCCGAGCTCGAACCCGCGCCTCGCGGCCTCTACACCGGTGCAATCGGCTGGCTCGATGCGCCAGAG
CCCAGCGATGGTGGCCTGTGCCGTTTCGCCATGTCCGTAGCCATTCGCACGCTAGTGCTGTCGCCGCGTGCGGCGGATGG
CTTGCGAGCCGGCGAGATGGGCGTTGGTGGTGGCATCGTGCACGACAGCGTGGCGGCCGACGAGTTTGCCGAGTGCGGCT
GGAAGGCGCGCTTCCTCACTCGCCATGATCCCGGCCTTACGCTGTTCGAGACCATGCACGTCGAAGACGGCCGCTGCCTT
CGCGGCGATCGGCACCTCGCGCGGTTGGCCTCGTCATGTGCTGCGCTTGGGTTTGCCTTCGACCGGCCGGCGGTCATGGC
CGCATTGACGGCCGAGATGGTCCGTCTGGGCGCCGGAAACTGGCGCCTGCGCATGAGCGTCGACAAACACGGCGAGCTGT
CGTTTGCCAGCGGCGCGCTGCGGCCACTGGCGGAAGCGACCGTCGGACTCGACATCGCCGACGAGCCGCTGCCCGACGCC
GACCCGCTGCGCCGGCACAAGACCAGCGCGCGCGCTGTCTACGACGCCGGCTGGCAGGCAGCGGAGCGCGCCGGCTGTTT
CGATCGCCTGTTCTTCAACACACGCGATGAATTGCTCGAGGGTGGCCGCAGCTCGGTATTCGTCAAGGTCGATGGAGAAT
GGCTGACGCCACCGCTGGCCGCGGACATCCTGCCCGGCGTGATGCGGGCGGTGGTGCTGGAGGAGGGCGATCCAATGCTC
GATGGTCCGGCTCGCGAGGCGGTTGTAACGCGGGCAATGCTGATGCGCGCGGAGGCAGTGCTGGCCGTCAATTCGCTGCG
CGGCGTGATGCGGGCAAGCTGGCGCTAG

Upstream 100 bases:

>100_bases
TGCATTTTCCCGCCTTCTTGTCGTGCCTCTCTCGCTTTCCTGCTCCGATCCCCAACCGTTCGTACTGCTGGACGATGCTA
CTGCGCCATCTGGCGAAGCG

Downstream 100 bases:

>100_bases
GCTGCGACGGCGAGCGCGCTCTACCGATGGTGAATATCCAGCAACCCATCGCCAAGCTTCCACCGCACCACACCGGGCAG
ATTGATCAGCTCGCGGTCGT

Product: Para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MSRLYTGLVREDRLPAGSDVALIDALLAEGWRQGWHATLFAPYEFGGALVGAPAHTDDRLPFHDGAVRLLWFRDMRRLDG
DAVRAWLPEPDAQAPAGLMNVAADTPREAFDTAIARIHAWIEAGDTYQVNFTQRIAFSSFGDPRALYAALRDAQPVPYGV
LACLPGDGWVLSLSPELFVQHDGSGRLLTRPMKGTAPLSGDPGQDAQAAAGLAADAKNRAENVMIVDLLRNDLGRIAQPG
SVEVPDRFVVQPFGAVLQMTSTVRATARAATRFGELFGALFPCGSITGAPKRRTMQIIAELEPAPRGLYTGAIGWLDAPE
PSDGGLCRFAMSVAIRTLVLSPRAADGLRAGEMGVGGGIVHDSVAADEFAECGWKARFLTRHDPGLTLFETMHVEDGRCL
RGDRHLARLASSCAALGFAFDRPAVMAALTAEMVRLGAGNWRLRMSVDKHGELSFASGALRPLAEATVGLDIADEPLPDA
DPLRRHKTSARAVYDAGWQAAERAGCFDRLFFNTRDELLEGGRSSVFVKVDGEWLTPPLAADILPGVMRAVVLEEGDPML
DGPAREAVVTRAMLMRAEAVLAVNSLRGVMRASWR

Sequences:

>Translated_595_residues
MSRLYTGLVREDRLPAGSDVALIDALLAEGWRQGWHATLFAPYEFGGALVGAPAHTDDRLPFHDGAVRLLWFRDMRRLDG
DAVRAWLPEPDAQAPAGLMNVAADTPREAFDTAIARIHAWIEAGDTYQVNFTQRIAFSSFGDPRALYAALRDAQPVPYGV
LACLPGDGWVLSLSPELFVQHDGSGRLLTRPMKGTAPLSGDPGQDAQAAAGLAADAKNRAENVMIVDLLRNDLGRIAQPG
SVEVPDRFVVQPFGAVLQMTSTVRATARAATRFGELFGALFPCGSITGAPKRRTMQIIAELEPAPRGLYTGAIGWLDAPE
PSDGGLCRFAMSVAIRTLVLSPRAADGLRAGEMGVGGGIVHDSVAADEFAECGWKARFLTRHDPGLTLFETMHVEDGRCL
RGDRHLARLASSCAALGFAFDRPAVMAALTAEMVRLGAGNWRLRMSVDKHGELSFASGALRPLAEATVGLDIADEPLPDA
DPLRRHKTSARAVYDAGWQAAERAGCFDRLFFNTRDELLEGGRSSVFVKVDGEWLTPPLAADILPGVMRAVVLEEGDPML
DGPAREAVVTRAMLMRAEAVLAVNSLRGVMRASWR
>Mature_594_residues
SRLYTGLVREDRLPAGSDVALIDALLAEGWRQGWHATLFAPYEFGGALVGAPAHTDDRLPFHDGAVRLLWFRDMRRLDGD
AVRAWLPEPDAQAPAGLMNVAADTPREAFDTAIARIHAWIEAGDTYQVNFTQRIAFSSFGDPRALYAALRDAQPVPYGVL
ACLPGDGWVLSLSPELFVQHDGSGRLLTRPMKGTAPLSGDPGQDAQAAAGLAADAKNRAENVMIVDLLRNDLGRIAQPGS
VEVPDRFVVQPFGAVLQMTSTVRATARAATRFGELFGALFPCGSITGAPKRRTMQIIAELEPAPRGLYTGAIGWLDAPEP
SDGGLCRFAMSVAIRTLVLSPRAADGLRAGEMGVGGGIVHDSVAADEFAECGWKARFLTRHDPGLTLFETMHVEDGRCLR
GDRHLARLASSCAALGFAFDRPAVMAALTAEMVRLGAGNWRLRMSVDKHGELSFASGALRPLAEATVGLDIADEPLPDAD
PLRRHKTSARAVYDAGWQAAERAGCFDRLFFNTRDELLEGGRSSVFVKVDGEWLTPPLAADILPGVMRAVVLEEGDPMLD
GPAREAVVTRAMLMRAEAVLAVNSLRGVMRASWR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=298, Percent_Identity=40.9395973154362, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1787518, Length=290, Percent_Identity=30.6896551724138, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786809, Length=214, Percent_Identity=25.7009345794392, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=293, Percent_Identity=34.8122866894198, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=289, Percent_Identity=26.643598615917, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 64049; Mature: 63918

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLYTGLVREDRLPAGSDVALIDALLAEGWRQGWHATLFAPYEFGGALVGAPAHTDDRL
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCCEEECCCCCCCCCC
PFHDGAVRLLWFRDMRRLDGDAVRAWLPEPDAQAPAGLMNVAADTPREAFDTAIARIHAW
CCCCCCEEEEEHHHHHHCCCCHHEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
IEAGDTYQVNFTQRIAFSSFGDPRALYAALRDAQPVPYGVLACLPGDGWVLSLSPELFVQ
HCCCCEEEEEEHHEEHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCEEEEE
HDGSGRLLTRPMKGTAPLSGDPGQDAQAAAGLAADAKNRAENVMIVDLLRNDLGRIAQPG
ECCCCCEEECCCCCCCCCCCCCCCCHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHCCCCC
SVEVPDRFVVQPFGAVLQMTSTVRATARAATRFGELFGALFPCGSITGAPKRRTMQIIAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LEPAPRGLYTGAIGWLDAPEPSDGGLCRFAMSVAIRTLVLSPRAADGLRAGEMGVGGGIV
CCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
HDSVAADEFAECGWKARFLTRHDPGLTLFETMHVEDGRCLRGDRHLARLASSCAALGFAF
CCCHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHC
DRPAVMAALTAEMVRLGAGNWRLRMSVDKHGELSFASGALRPLAEATVGLDIADEPLPDA
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC
DPLRRHKTSARAVYDAGWQAAERAGCFDRLFFNTRDELLEGGRSSVFVKVDGEWLTPPLA
CHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCCHH
ADILPGVMRAVVLEEGDPMLDGPAREAVVTRAMLMRAEAVLAVNSLRGVMRASWR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLYTGLVREDRLPAGSDVALIDALLAEGWRQGWHATLFAPYEFGGALVGAPAHTDDRL
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCCEEECCCCCCCCCC
PFHDGAVRLLWFRDMRRLDGDAVRAWLPEPDAQAPAGLMNVAADTPREAFDTAIARIHAW
CCCCCCEEEEEHHHHHHCCCCHHEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
IEAGDTYQVNFTQRIAFSSFGDPRALYAALRDAQPVPYGVLACLPGDGWVLSLSPELFVQ
HCCCCEEEEEEHHEEHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCEEEEE
HDGSGRLLTRPMKGTAPLSGDPGQDAQAAAGLAADAKNRAENVMIVDLLRNDLGRIAQPG
ECCCCCEEECCCCCCCCCCCCCCCCHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHCCCCC
SVEVPDRFVVQPFGAVLQMTSTVRATARAATRFGELFGALFPCGSITGAPKRRTMQIIAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LEPAPRGLYTGAIGWLDAPEPSDGGLCRFAMSVAIRTLVLSPRAADGLRAGEMGVGGGIV
CCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
HDSVAADEFAECGWKARFLTRHDPGLTLFETMHVEDGRCLRGDRHLARLASSCAALGFAF
CCCHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHC
DRPAVMAALTAEMVRLGAGNWRLRMSVDKHGELSFASGALRPLAEATVGLDIADEPLPDA
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC
DPLRRHKTSARAVYDAGWQAAERAGCFDRLFFNTRDELLEGGRSSVFVKVDGEWLTPPLA
CHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCCHH
ADILPGVMRAVVLEEGDPMLDGPAREAVVTRAMLMRAEAVLAVNSLRGVMRASWR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]