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The map label for this gene is nadA [H]

Identifier: 73542422

GI number: 73542422

Start: 3003149

End: 3004303

Strand: Reverse

Name: nadA [H]

Synonym: Reut_A2737

Alternate gene names: 73542422

Gene position: 3004303-3003149 (Counterclockwise)

Preceding gene: 73542423

Following gene: 73542421

Centisome position: 78.92

GC content: 64.68

Gene sequence:

>1155_bases
ATGACCCCACAATCGATCAAGACCGTCGAGTTCGAAAAGCCGGACCTGACGGATACCGAAAGCCCCGCCGGCGGTAGCTG
CGTGGCCCACGCCTGGGCCAAGGTGCCCCCCGTGCTGACGCCGGACGAACGCCAGGCGCTCAAGGCGCGCATCAAGCGGT
TGCTGAAGGAACGCAATGCCGTGCTGGTTGCCCACTATTACGTGGACGCCGACCTGCAGGACCTCGCCGAAGAAACCGGC
GGCTGCGTCTCCGACTCGCTCGAAATGGCCCGCTTCGGCCGTGACCATTCGGCCCAGACCCTGGTCGTGGCCGGCGTGCG
CTTCATGGGCGAAACCGCCAAGATCCTGAGTCCGGAAAAGACCATCCTGATGCCGGACCTGGACGCGACCTGCTCGCTCG
ACCTCGGCTGCCCCGCCGACGAGTTTGCGGCGTTCTGTGACGCGCATCCGGATCGCACCGTGGTCGTGTATGCGAACACC
AGCGCGGCGGTGAAGGCGCGCGCGGACTGGATGGTGACGTCCAGCATTGGCCTGAAGATCGTGCAGCACCTGCATGCGCG
CGGCGAGAAGATTCTGTGGGCGCCCGACAAGCACCTCGGCAGCTATATCCAGAAGGAGACCGGCGCCGACATGCTGCTGT
GGCAGGGCTCGTGCCTGGTCCATGACGAGTTCAAGGGCATCGAACTCGACCTGCTGCGCCGCGAATTTCCGAAGGCCAAG
ATTCTCGTGCATCCGGAGTCGCCGGCCAATGTGGTCGAGCAGGCCGATGTGGTGGGCTCCACGTCGCAACTCATCGCGGC
CGCGCAGGAACTGGACGCGACCGAGTTCATCGTGGCGACCGACAACGGCATCCTGCACAAGATGCGGATGGCGGCACCGG
GCAAGCATTTCATCGAAGCTCCGACGGCGGGCAACAGCGCTACCTGCAAGAGCTGCGCACATTGCCCGTGGATGGCGATG
AATGCGCTGTCGAACCTGGCCGAAGTGCTCGAGACCGGCCGCAACGAGATCCATGTGGATCCGGCCACCGGCCGACAGGC
GGTGACCTGCATCAATCGCATGCTCGACTTCGCTGCGCAGCAGAAGGCCAATGTCCGGCCGGCGGCTGACCTTGCGAAGG
AACAGGCCTTGTTCCAGGGAATCGGTCCGGCATGA

Upstream 100 bases:

>100_bases
AAAGCCCCGCCCATGGCGGGGCTTTTGTTTTAGATAAACTCCCCCAGGTTCTGGCTGTCCGCATGATGTTGCATGCGTGA
GGTCTAGAGGAGTACCGGAG

Downstream 100 bases:

>100_bases
GTGTGAATTCGGTGTTCGATAGCTATGGTCCGGCGCTGAAGTCGGCGCTGGAAGCCAACGTCAGCGCGGCGATCGCCGAG
GACGTCGGCAGTGGTGATCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTPQSIKTVEFEKPDLTDTESPAGGSCVAHAWAKVPPVLTPDERQALKARIKRLLKERNAVLVAHYYVDADLQDLAEETG
GCVSDSLEMARFGRDHSAQTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADEFAAFCDAHPDRTVVVYANT
SAAVKARADWMVTSSIGLKIVQHLHARGEKILWAPDKHLGSYIQKETGADMLLWQGSCLVHDEFKGIELDLLRREFPKAK
ILVHPESPANVVEQADVVGSTSQLIAAAQELDATEFIVATDNGILHKMRMAAPGKHFIEAPTAGNSATCKSCAHCPWMAM
NALSNLAEVLETGRNEIHVDPATGRQAVTCINRMLDFAAQQKANVRPAADLAKEQALFQGIGPA

Sequences:

>Translated_384_residues
MTPQSIKTVEFEKPDLTDTESPAGGSCVAHAWAKVPPVLTPDERQALKARIKRLLKERNAVLVAHYYVDADLQDLAEETG
GCVSDSLEMARFGRDHSAQTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADEFAAFCDAHPDRTVVVYANT
SAAVKARADWMVTSSIGLKIVQHLHARGEKILWAPDKHLGSYIQKETGADMLLWQGSCLVHDEFKGIELDLLRREFPKAK
ILVHPESPANVVEQADVVGSTSQLIAAAQELDATEFIVATDNGILHKMRMAAPGKHFIEAPTAGNSATCKSCAHCPWMAM
NALSNLAEVLETGRNEIHVDPATGRQAVTCINRMLDFAAQQKANVRPAADLAKEQALFQGIGPA
>Mature_383_residues
TPQSIKTVEFEKPDLTDTESPAGGSCVAHAWAKVPPVLTPDERQALKARIKRLLKERNAVLVAHYYVDADLQDLAEETGG
CVSDSLEMARFGRDHSAQTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADEFAAFCDAHPDRTVVVYANTS
AAVKARADWMVTSSIGLKIVQHLHARGEKILWAPDKHLGSYIQKETGADMLLWQGSCLVHDEFKGIELDLLRREFPKAKI
LVHPESPANVVEQADVVGSTSQLIAAAQELDATEFIVATDNGILHKMRMAAPGKHFIEAPTAGNSATCKSCAHCPWMAMN
ALSNLAEVLETGRNEIHVDPATGRQAVTCINRMLDFAAQQKANVRPAADLAKEQALFQGIGPA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=329, Percent_Identity=68.0851063829787, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41568; Mature: 41437

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQSIKTVEFEKPDLTDTESPAGGSCVAHAWAKVPPVLTPDERQALKARIKRLLKERNA
CCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
VLVAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHSAQTLVVAGVRFMGETAKILSPEK
EEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCC
TILMPDLDATCSLDLGCPADEFAAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKI
EEEECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VQHLHARGEKILWAPDKHLGSYIQKETGADMLLWQGSCLVHDEFKGIELDLLRREFPKAK
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHCCCCE
ILVHPESPANVVEQADVVGSTSQLIAAAQELDATEFIVATDNGILHKMRMAAPGKHFIEA
EEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEEC
PTAGNSATCKSCAHCPWMAMNALSNLAEVLETGRNEIHVDPATGRQAVTCINRMLDFAAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
QKANVRPAADLAKEQALFQGIGPA
HCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPQSIKTVEFEKPDLTDTESPAGGSCVAHAWAKVPPVLTPDERQALKARIKRLLKERNA
CCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
VLVAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHSAQTLVVAGVRFMGETAKILSPEK
EEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCC
TILMPDLDATCSLDLGCPADEFAAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKI
EEEECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VQHLHARGEKILWAPDKHLGSYIQKETGADMLLWQGSCLVHDEFKGIELDLLRREFPKAK
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHCCCCE
ILVHPESPANVVEQADVVGSTSQLIAAAQELDATEFIVATDNGILHKMRMAAPGKHFIEA
EEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEEC
PTAGNSATCKSCAHCPWMAMNALSNLAEVLETGRNEIHVDPATGRQAVTCINRMLDFAAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
QKANVRPAADLAKEQALFQGIGPA
HCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA