BacMap

Definition	Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession	NC_007347
Length	3,806,533

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The map label for this gene is fabG [H]

Identifier: 73542190

GI number: 73542190

Start: 2745075

End: 2745863

Strand: Reverse

Name: fabG [H]

Synonym: Reut_A2505

Alternate gene names: 73542190

Gene position: 2745863-2745075 (Counterclockwise)

Preceding gene: 73542191

Following gene: 73542189

Centisome position: 72.14

GC content: 69.46

Gene sequence:

>789_bases
ATGGATCTGGGACTGCGTGGCAAGCATGCACTGGTGTGTGGCGCGAGCAAGGGCCTTGGTTTCGCCTGCGCGGACGCGCT
GGCGGCCGAAGGCGTTGATGTCGTGATCGTGGCGCGCGGCGCCGAGGCGCTGGAAAAGGCCGCCGCGGGCCTGCGTGCAC
GCCATGGCCGCCGCGTGGTCGCCGTGGCCACGGACATCACCAAGCCGGAAGGCCGCAAGGCCGCGCTGGACGCCGTGGCC
AAGCTCGGCGACCTCGATATCCTCGTCAACAACGCCGGCGGCCCGCCCCCGGGCAACTTCCGCGACTGGGACCGCGAAGC
GTGGCTGGCCGCGCTCGATGCCAACATGCTGACCCCGATCGAATTGATCAAGGCCACCGTCGACGGCATGATCGCGCGCA
AGTGGGGCCGCATCATCAACATCACGAGCGGCGCGGTGAAGGCGCCGATCGATGTGCTGGGCCTGTCCAACGGCGCGCGC
TCGGGCCTGACCGGCTTCATCGCCGGCCTGGCGCGCGAAGTGGCGCAGCACGGCGTGACCGTCAACAACCTGCTGCCGGG
GCCGTTCAATACCGACCGCCTGTTCAAGACCATGGAAGGCGCCGCCCAGAAGGCGAACCTGACCGTGGATGAAGTCGCGC
AACGCCGCGCCGCGCTGAACCCGTCGCGGCGCTTCGGCGACCCGGCCGAGTTCGGTGCAACGTGTGCGTTCCTGTGCAGC
CGACAGGCCGCGTACATCACGGCGCAGAACATCCTGCTCGACGGCGGCGCCTACCCCGGCACGTTCTGA

Upstream 100 bases:

>100_bases
ACCTGCTGTCGGCGCGCAAAGCGTGATAACGCACCAAGCCGCGCGACGACAGCGAACCTGAAAGCTATACAAGCAAACAA
GCCAACAAGGAGAGCGAGAA

Downstream 100 bases:

>100_bases
ACCCGGCGCGGCCCCGCTACTGGCCGCACTCCACCCGCAGTCGCTTACCGCAACAAGGATTCTTGATGACCCGCCCACGT
ATCGCCCTGATTGCACACGA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MDLGLRGKHALVCGASKGLGFACADALAAEGVDVVIVARGAEALEKAAAGLRARHGRRVVAVATDITKPEGRKAALDAVA
KLGDLDILVNNAGGPPPGNFRDWDREAWLAALDANMLTPIELIKATVDGMIARKWGRIINITSGAVKAPIDVLGLSNGAR
SGLTGFIAGLAREVAQHGVTVNNLLPGPFNTDRLFKTMEGAAQKANLTVDEVAQRRAALNPSRRFGDPAEFGATCAFLCS
RQAAYITAQNILLDGGAYPGTF

Sequences:

>Translated_262_residues
MDLGLRGKHALVCGASKGLGFACADALAAEGVDVVIVARGAEALEKAAAGLRARHGRRVVAVATDITKPEGRKAALDAVA
KLGDLDILVNNAGGPPPGNFRDWDREAWLAALDANMLTPIELIKATVDGMIARKWGRIINITSGAVKAPIDVLGLSNGAR
SGLTGFIAGLAREVAQHGVTVNNLLPGPFNTDRLFKTMEGAAQKANLTVDEVAQRRAALNPSRRFGDPAEFGATCAFLCS
RQAAYITAQNILLDGGAYPGTF
>Mature_262_residues
MDLGLRGKHALVCGASKGLGFACADALAAEGVDVVIVARGAEALEKAAAGLRARHGRRVVAVATDITKPEGRKAALDAVA
KLGDLDILVNNAGGPPPGNFRDWDREAWLAALDANMLTPIELIKATVDGMIARKWGRIINITSGAVKAPIDVLGLSNGAR
SGLTGFIAGLAREVAQHGVTVNNLLPGPFNTDRLFKTMEGAAQKANLTVDEVAQRRAALNPSRRFGDPAEFGATCAFLCS
RQAAYITAQNILLDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.8897637795276, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=28.8537549407115, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=28.7313432835821, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=28.804347826087, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=29.3532338308458, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=29.8969072164948, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=26.2548262548263, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=32.967032967033, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI66933014, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=26.6304347826087, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=34.3629343629344, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=35.9073359073359, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.2352941176471, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=29.6577946768061, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.718875502008, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=30.3370786516854, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=28.125, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=28.6274509803922, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=24.4186046511628, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=31.2977099236641, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=32.4626865671642, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=30.5343511450382, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.1787072243346, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=29.0566037735849, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.9242424242424, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=28.735632183908, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=28.2527881040892, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=28.6792452830189, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=29.3436293436293, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.4339622641509, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.7153558052434, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=29.7709923664122, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=269, Percent_Identity=29.7397769516729, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=28.968253968254, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=263, Percent_Identity=24.3346007604563, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=28.8659793814433, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=30.859375, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=29.6875, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=28.1368821292776, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=28.957528957529, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27294; Mature: 27294

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLRGKHALVCGASKGLGFACADALAAEGVDVVIVARGAEALEKAAAGLRARHGRRVV
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
AVATDITKPEGRKAALDAVAKLGDLDILVNNAGGPPPGNFRDWDREAWLAALDANMLTPI
EEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHH
ELIKATVDGMIARKWGRIINITSGAVKAPIDVLGLSNGARSGLTGFIAGLAREVAQHGVT
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCE
VNNLLPGPFNTDRLFKTMEGAAQKANLTVDEVAQRRAALNPSRRFGDPAEFGATCAFLCS
ECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHC
RQAAYITAQNILLDGGAYPGTF
CCHHEEEECEEEEECCCCCCCC
>Mature Secondary Structure
MDLGLRGKHALVCGASKGLGFACADALAAEGVDVVIVARGAEALEKAAAGLRARHGRRVV
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
AVATDITKPEGRKAALDAVAKLGDLDILVNNAGGPPPGNFRDWDREAWLAALDANMLTPI
EEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHH
ELIKATVDGMIARKWGRIINITSGAVKAPIDVLGLSNGARSGLTGFIAGLAREVAQHGVT
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCE
VNNLLPGPFNTDRLFKTMEGAAQKANLTVDEVAQRRAALNPSRRFGDPAEFGATCAFLCS
ECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHC
RQAAYITAQNILLDGGAYPGTF
CCHHEEEECEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]