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The map label for this gene is mmlH [H]

Identifier: 73542134

GI number: 73542134

Start: 2685723

End: 2687012

Strand: Direct

Name: mmlH [H]

Synonym: Reut_A2448

Alternate gene names: 73542134

Gene position: 2685723-2687012 (Clockwise)

Preceding gene: 73542132

Following gene: 73542135

Centisome position: 70.56

GC content: 63.64

Gene sequence:

>1290_bases
ATGTGGCTTAAGGAAACAAACCGAGAGGAGCGCAGGACGCTCTTCGCCGCCTTCGTCGGCTATGGCGTCGATGCCTTCGA
CTACATGATCTACACGTTCATGATCCCGACCTTCATCCTGGTCTGGGGCATGACGAAGGCCGAGGCCGGCTACATTGCCA
CCGGCGCCCTCATCAGTTCCGCGATCGGCGGATGGCTGGCCGGCATCCTGGCCGACAAGTACGGCCGGGTCCGGATCCTG
CAGCTCACGGTGCTCTGGTTCAGCCTGTTCACGTTCCTGAGCGGCTTCACCCAGTCGCCCGACCAGCTGTTCATCACGCG
CATGCTGCAGGGACTCGGCTTCGGCGGCGAATGGTCCGTGGGTTCCGTCCTGATTGCCGAGATGATCCGCGCTCGCCATC
GCGGCAAGGCCGTGGGGCTGGTGCAAAGCAGCTGGGCCGTGGGTTGGGGGATTTCCGCCATCGCCTTCTGGGCGGTCTAC
GCGCTGATCGATCAGCAACATGCGTGGCGCGTGCTGTTCTGGCTCGGCGCGCTGCCGGCCCTGTTCATCCTCTATATCCG
CCGCAACATCAGCGAGCCGGAGGTGTACCGCGAGACCAAGGCCAAGCTCGCCCGCACAGGCGAAAGTAACAGCTTCATGC
TGATCTTCAAGCCGGGCGTGCTGGGTGTCACGCTGATGGCAAGCCTGCTGGCTACCGGCATGCAGGGCGCCTACTACTCC
GTCACGACCTGGTTGCCGACCTACCTCAAGATGGAGCGCCATCTCTCCGTGCTCAACACCAGCGGCTACCTGATGGTGCT
GATCGCGGGGTCGTTCGCCGGCTACCTGACCAGCGCATGGCTTTCCGACCAGCTTGGCCGCAAGCGCTGCTTCATGCTGT
TTGCCGTGAGTGCCGCGGTGCTCGTGACCTGCTACACCCAGTTGCCGATTACCGATGGAGCCATGATGGTGCTGGGCTTC
CCGCTCGGCTTCTTCCTGTCGGGCATTTTCTCGGGCATGGGGGCCTACCTCACGGAACTGTTCCCAAGCCATATTCGCGG
CTCCGGCCAGGGCTTTTGCTACAACTTCGGGCGTGCCGTGGGCGCGGTATTTCCCGCGATGATCGGCCACATGAGCACGT
CGATGCCATTGGGCACGGCCATCGGTTACCTCGCCGCCGGCGCCTACACGCTGGTCGTGATTGCCTGCCTGCTGCTGCCG
GAAACCCAGGGACGCGATCTGACCAACGACTCGGAGCCGTCGAATCCGCAATTGGCACCGGCCGGCGCCACGCAAGCCGC
CGAGCATTGA

Upstream 100 bases:

>100_bases
GTTACCCGGCGCCGCAGGCTGACCCGGACATCGTTGAGAAAGTGGGTGCACGACGACGTCCTCCCTACATCCGCCGTCTT
CCTGGAAGGAGAACGCAACC

Downstream 100 bases:

>100_bases
CCCGGGACGGCACGCGATTCGGCTGACCCATGTCTGCCCGCAACACGAAGAACGGATATCACCATGACAAACCACATGCT
TGACGAGGTCCGCTCGGCCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MWLKETNREERRTLFAAFVGYGVDAFDYMIYTFMIPTFILVWGMTKAEAGYIATGALISSAIGGWLAGILADKYGRVRIL
QLTVLWFSLFTFLSGFTQSPDQLFITRMLQGLGFGGEWSVGSVLIAEMIRARHRGKAVGLVQSSWAVGWGISAIAFWAVY
ALIDQQHAWRVLFWLGALPALFILYIRRNISEPEVYRETKAKLARTGESNSFMLIFKPGVLGVTLMASLLATGMQGAYYS
VTTWLPTYLKMERHLSVLNTSGYLMVLIAGSFAGYLTSAWLSDQLGRKRCFMLFAVSAAVLVTCYTQLPITDGAMMVLGF
PLGFFLSGIFSGMGAYLTELFPSHIRGSGQGFCYNFGRAVGAVFPAMIGHMSTSMPLGTAIGYLAAGAYTLVVIACLLLP
ETQGRDLTNDSEPSNPQLAPAGATQAAEH

Sequences:

>Translated_429_residues
MWLKETNREERRTLFAAFVGYGVDAFDYMIYTFMIPTFILVWGMTKAEAGYIATGALISSAIGGWLAGILADKYGRVRIL
QLTVLWFSLFTFLSGFTQSPDQLFITRMLQGLGFGGEWSVGSVLIAEMIRARHRGKAVGLVQSSWAVGWGISAIAFWAVY
ALIDQQHAWRVLFWLGALPALFILYIRRNISEPEVYRETKAKLARTGESNSFMLIFKPGVLGVTLMASLLATGMQGAYYS
VTTWLPTYLKMERHLSVLNTSGYLMVLIAGSFAGYLTSAWLSDQLGRKRCFMLFAVSAAVLVTCYTQLPITDGAMMVLGF
PLGFFLSGIFSGMGAYLTELFPSHIRGSGQGFCYNFGRAVGAVFPAMIGHMSTSMPLGTAIGYLAAGAYTLVVIACLLLP
ETQGRDLTNDSEPSNPQLAPAGATQAAEH
>Mature_429_residues
MWLKETNREERRTLFAAFVGYGVDAFDYMIYTFMIPTFILVWGMTKAEAGYIATGALISSAIGGWLAGILADKYGRVRIL
QLTVLWFSLFTFLSGFTQSPDQLFITRMLQGLGFGGEWSVGSVLIAEMIRARHRGKAVGLVQSSWAVGWGISAIAFWAVY
ALIDQQHAWRVLFWLGALPALFILYIRRNISEPEVYRETKAKLARTGESNSFMLIFKPGVLGVTLMASLLATGMQGAYYS
VTTWLPTYLKMERHLSVLNTSGYLMVLIAGSFAGYLTSAWLSDQLGRKRCFMLFAVSAAVLVTCYTQLPITDGAMMVLGF
PLGFFLSGIFSGMGAYLTELFPSHIRGSGQGFCYNFGRAVGAVFPAMIGHMSTSMPLGTAIGYLAAGAYTLVVIACLLLP
ETQGRDLTNDSEPSNPQLAPAGATQAAEH

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=381, Percent_Identity=26.7716535433071, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87082231, Length=451, Percent_Identity=26.8292682926829, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1790550, Length=392, Percent_Identity=25.5102040816327, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081723, Length=355, Percent_Identity=25.6338028169014, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082159, Length=378, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788068, Length=347, Percent_Identity=25.6484149855908, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788942, Length=409, Percent_Identity=25.6723716381418, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789515, Length=371, Percent_Identity=24.7978436657682, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786229, Length=397, Percent_Identity=22.6700251889169, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789152, Length=403, Percent_Identity=23.8213399503722, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46886; Mature: 46886

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLKETNREERRTLFAAFVGYGVDAFDYMIYTFMIPTFILVWGMTKAEAGYIATGALISS
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AIGGWLAGILADKYGRVRILQLTVLWFSLFTFLSGFTQSPDQLFITRMLQGLGFGGEWSV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
GSVLIAEMIRARHRGKAVGLVQSSWAVGWGISAIAFWAVYALIDQQHAWRVLFWLGALPA
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LFILYIRRNISEPEVYRETKAKLARTGESNSFMLIFKPGVLGVTLMASLLATGMQGAYYS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEE
VTTWLPTYLKMERHLSVLNTSGYLMVLIAGSFAGYLTSAWLSDQLGRKRCFMLFAVSAAV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVTCYTQLPITDGAMMVLGFPLGFFLSGIFSGMGAYLTELFPSHIRGSGQGFCYNFGRAV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GAVFPAMIGHMSTSMPLGTAIGYLAAGAYTLVVIACLLLPETQGRDLTNDSEPSNPQLAP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
AGATQAAEH
CCCCCCCCC
>Mature Secondary Structure
MWLKETNREERRTLFAAFVGYGVDAFDYMIYTFMIPTFILVWGMTKAEAGYIATGALISS
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AIGGWLAGILADKYGRVRILQLTVLWFSLFTFLSGFTQSPDQLFITRMLQGLGFGGEWSV
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
GSVLIAEMIRARHRGKAVGLVQSSWAVGWGISAIAFWAVYALIDQQHAWRVLFWLGALPA
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LFILYIRRNISEPEVYRETKAKLARTGESNSFMLIFKPGVLGVTLMASLLATGMQGAYYS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEE
VTTWLPTYLKMERHLSVLNTSGYLMVLIAGSFAGYLTSAWLSDQLGRKRCFMLFAVSAAV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVTCYTQLPITDGAMMVLGFPLGFFLSGIFSGMGAYLTELFPSHIRGSGQGFCYNFGRAV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GAVFPAMIGHMSTSMPLGTAIGYLAAGAYTLVVIACLLLPETQGRDLTNDSEPSNPQLAP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
AGATQAAEH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]