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The map label for this gene is nahR [H]

Identifier: 73542110

GI number: 73542110

Start: 2655136

End: 2656320

Strand: Reverse

Name: nahR [H]

Synonym: Reut_A2424

Alternate gene names: 73542110

Gene position: 2656320-2655136 (Counterclockwise)

Preceding gene: 73542119

Following gene: 73542108

Centisome position: 69.78

GC content: 62.62

Gene sequence:

>1185_bases
ATGGTTTGCGTCTCCATGGTCTTCATCTCGTTCTGTGATGGCGGAAACATAGCACCGGCGCGTTTCATGCAATATTCGGC
CCAGGTGATATGCCCCATCAGGATGCCCGTCCATGGGGTTCCGCTGTCCCCTTATCACGGCGGATTGACCAATGGCGGGT
TGCGTGACATACACTATGCGCCGTTCCCTTCCCCCACGCCAGCCTCCCGGCCGCACGCCGGCAGGGCCCCTATTGCCATG
CACGGACGCGACCATCTCGATACCTATTTGCTGCGGGTGCTCCACACCCTGCTGACCGAGCAGAGCGTGACGCGCACGGC
TGTGCGCCTGGGCCAGTCGCAGCCGGCCATCAGCAATACGCTAAAGCGCCTGCGCGAGATCACCGGCGACGCCATTTTGG
TGCGGGGCAAAAGCGGCATGGTGCCAACCGAACGGGGGCGGGAATTGCTGGAGCTGGCCGAGCAGAGCCTGGCGGCGATG
GACCGTATCGCGCGTCCTCCGCAGCAGTTCGATCCGGCCACGACCACGCGGACGTTTCACCTTGGCGCCCCGGATTACCT
GGATGCCTTCTTCCTGCCAAACATCGTCGAGCGCGTGCGCCGGCTGGCGCCCGGCGCCAAGCTGTTCGTACATCCTATGA
CGTCGTCGAGCGACTTTCTGGAGGACCTGGAGCAGGGGCAGCTCGACATCGTCATTGGCAACTGGCTGTCGCCGCCCGAG
CATCTGCATATCTCGCCGTTATTTGATGACGAGGTGGTTTGCATGCTCGGTGCCCAGCATCCGCTGGCGCGCAAAGGCCT
GACGCTGAAGCACTACCTGGAGATGCCTCATCTGGCACCTGCGCCCTATGCTTCGATGCAACGCAGCATGATCGATCAGG
CGCTCGCCGAGCAGGGGTACAAGCGCAATATCCAGGTGACGCTGCCGTACTTTGGGCTGGTGCCGTATGTGCTGATGAAA
ACCGATATGGTGTTCACCACCGGCCGCCAGTTTGCTGCGCACTATGCGCAGTATTTGCCGATCCGGATGGTGCCGTCTCC
GGTGACGTTCCCGCGCATGCGGTTCTACCAGCTCTGGCATGAGCGGTGCCATGCGGCCCCGGATGTGATGTGGATGCGGA
GGATGATCGCGGAGGTGGCGACGGATTTGCCGCAGTTGCCGAGGTTGGAGGCGGAGGCGGGATAG

Upstream 100 bases:

>100_bases
GGTGCCGGTGCAGCGCGCGTCCTCTCGCAGGTACTGCAGCACGGTCCTGGTAACGGGGGCGTCGGATACTTCCCTGACCT
GGCCGCGGTGGAAAAAGCGG

Downstream 100 bases:

>100_bases
AGGTAGCTGCCTTTGGTGTGGTTTTACCCCTCGACTTCCGGATTTACCAGCGTCATATCTGACCCATACGGGTCTTCTGC
CCGCACCACCACCACGGTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MVCVSMVFISFCDGGNIAPARFMQYSAQVICPIRMPVHGVPLSPYHGGLTNGGLRDIHYAPFPSPTPASRPHAGRAPIAM
HGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLELAEQSLAAM
DRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTSSSDFLEDLEQGQLDIVIGNWLSPPE
HLHISPLFDDEVVCMLGAQHPLARKGLTLKHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLMK
TDMVFTTGRQFAAHYAQYLPIRMVPSPVTFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEAEAG

Sequences:

>Translated_394_residues
MVCVSMVFISFCDGGNIAPARFMQYSAQVICPIRMPVHGVPLSPYHGGLTNGGLRDIHYAPFPSPTPASRPHAGRAPIAM
HGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLELAEQSLAAM
DRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTSSSDFLEDLEQGQLDIVIGNWLSPPE
HLHISPLFDDEVVCMLGAQHPLARKGLTLKHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLMK
TDMVFTTGRQFAAHYAQYLPIRMVPSPVTFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEAEAG
>Mature_394_residues
MVCVSMVFISFCDGGNIAPARFMQYSAQVICPIRMPVHGVPLSPYHGGLTNGGLRDIHYAPFPSPTPASRPHAGRAPIAM
HGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLELAEQSLAAM
DRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTSSSDFLEDLEQGQLDIVIGNWLSPPE
HLHISPLFDDEVVCMLGAQHPLARKGLTLKHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLMK
TDMVFTTGRQFAAHYAQYLPIRMVPSPVTFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEAEAG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=28.3387622149837, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=27.6679841897233, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=297, Percent_Identity=23.2323232323232, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 44202; Mature: 44202

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCVSMVFISFCDGGNIAPARFMQYSAQVICPIRMPVHGVPLSPYHGGLTNGGLRDIHYA
CHHHHEEHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PFPSPTPASRPHAGRAPIAMHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNT
CCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LKRLREITGDAILVRGKSGMVPTERGRELLELAEQSLAAMDRIARPPQQFDPATTTRTFH
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEE
LGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTSSSDFLEDLEQGQLDIVIGNWLSPPE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCCCCC
HLHISPLFDDEVVCMLGAQHPLARKGLTLKHYLEMPHLAPAPYASMQRSMIDQALAEQGY
CEEECCCCCCCEEEEECCCCCHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
KRNIQVTLPYFGLVPYVLMKTDMVFTTGRQFAAHYAQYLPIRMVPSPVTFPRMRFYQLWH
CCCEEEEECHHHHHHHHHHHHCHHEECCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHH
ERCHAAPDVMWMRRMIAEVATDLPQLPRLEAEAG
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVCVSMVFISFCDGGNIAPARFMQYSAQVICPIRMPVHGVPLSPYHGGLTNGGLRDIHYA
CHHHHEEHHHHCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PFPSPTPASRPHAGRAPIAMHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNT
CCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LKRLREITGDAILVRGKSGMVPTERGRELLELAEQSLAAMDRIARPPQQFDPATTTRTFH
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEE
LGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTSSSDFLEDLEQGQLDIVIGNWLSPPE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCCCCC
HLHISPLFDDEVVCMLGAQHPLARKGLTLKHYLEMPHLAPAPYASMQRSMIDQALAEQGY
CEEECCCCCCCEEEEECCCCCHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
KRNIQVTLPYFGLVPYVLMKTDMVFTTGRQFAAHYAQYLPIRMVPSPVTFPRMRFYQLWH
CCCEEEEECHHHHHHHHHHHHCHHEECCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHH
ERCHAAPDVMWMRRMIAEVATDLPQLPRLEAEAG
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]