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The map label for this gene is ftsK1 [H]

Identifier: 73542061

GI number: 73542061

Start: 2617317

End: 2618195

Strand: Reverse

Name: ftsK1 [H]

Synonym: Reut_A2375

Alternate gene names: 73542061

Gene position: 2618195-2617317 (Counterclockwise)

Preceding gene: 73542062

Following gene: 73542060

Centisome position: 68.78

GC content: 63.14

Gene sequence:

>879_bases
ATGAGCCAATCGCCCGAATTCAAAGCCACCATGAACATGACCGCCAACACCCTTGGCAAGGACCTGCTGTCCGTCCTGGT
GCAGGAGATCAAGCTGATGCCCGACACCTGGGTGAAGCTGTCCGAGAAGAAGCAGAACGACATCATCGACCGCCTGCGAA
GCCGCGTGGACGCATCGGTGAAGATGGCTGTTCACCTGATCGCGGCCAACGGTCGTACGGTGGTGCAGGGCGATCTGGAC
AAGATCACCATCAAGGACGGCGCGCAGGCGCTGATCAAGATCGGCAAGTCGGTGTCCGCGCTGCATGAGCTGGCCGAGGC
GCAAGGCCAGGCCGTGCTGCTCGTCCTGAGTGGCGGCGAAGGCCAATACAACGGTGGCATGGACGAGGTACGCGGCGAGT
CCGACCAGCGCTCGTTCGAGATGGGCCGCGAGTACACCGACGGCGATGGTGATGGCATGCCGGATGCCGATGACAACGTG
GTAGACGCCGAGTACGTCGAAGAGCCGCGCGCGATCGAGCACCAGCCCCTGAAGGAAGAGCTCGACGCCGCCTACGAGGA
AGGCCACAAAGCCGCCTCCGAGGGCAAGCCTCAAAGCGATTGCCCCGTCATGGCTGGCGCGCTGTGCATCGAATGGGTGA
AGGGCTGGAAGGACTGGCACGACGAGCATCCCCAGGAAGACCCGCTGTACGTCGACGTAGAGGCCTTCGTGGTTGCCGAG
CAGCGCGTGTCCATCAGCATGGTCCAGCGCCATTTCAAGATCGGCTACAACCGCGCCGCGCGCCTGATCGAGCGACTGGA
AGCCAACGGCGTCGTCAGCGCCATGGACGCCGACGGCCAGCGCAAGGTCCTGAAGAGCACCGAAGAACAAGAGGGGTAA

Upstream 100 bases:

>100_bases
GACTGCCCGCGCGGACGGCTGTAGCGCGGGAGGAAGAACAGCGCCGCGCCGCCGATTTGCTGAGGCGCGGCCCGCACGCA
AACACGCACAGGACACCGAA

Downstream 100 bases:

>100_bases
GACGCCATGCGTATCACCGCCATCCACGCCCGCAACTTCCTCGGCATCCGGGCAGCCGACATCATCACGGCGACCCCGGT
GTCGCTGATCTGCGGCCCCA

Product: putative DNA segregation ATPase FtsK/SpoIIIE and related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSQSPEFKATMNMTANTLGKDLLSVLVQEIKLMPDTWVKLSEKKQNDIIDRLRSRVDASVKMAVHLIAANGRTVVQGDLD
KITIKDGAQALIKIGKSVSALHELAEAQGQAVLLVLSGGEGQYNGGMDEVRGESDQRSFEMGREYTDGDGDGMPDADDNV
VDAEYVEEPRAIEHQPLKEELDAAYEEGHKAASEGKPQSDCPVMAGALCIEWVKGWKDWHDEHPQEDPLYVDVEAFVVAE
QRVSISMVQRHFKIGYNRAARLIERLEANGVVSAMDADGQRKVLKSTEEQEG

Sequences:

>Translated_292_residues
MSQSPEFKATMNMTANTLGKDLLSVLVQEIKLMPDTWVKLSEKKQNDIIDRLRSRVDASVKMAVHLIAANGRTVVQGDLD
KITIKDGAQALIKIGKSVSALHELAEAQGQAVLLVLSGGEGQYNGGMDEVRGESDQRSFEMGREYTDGDGDGMPDADDNV
VDAEYVEEPRAIEHQPLKEELDAAYEEGHKAASEGKPQSDCPVMAGALCIEWVKGWKDWHDEHPQEDPLYVDVEAFVVAE
QRVSISMVQRHFKIGYNRAARLIERLEANGVVSAMDADGQRKVLKSTEEQEG
>Mature_291_residues
SQSPEFKATMNMTANTLGKDLLSVLVQEIKLMPDTWVKLSEKKQNDIIDRLRSRVDASVKMAVHLIAANGRTVVQGDLDK
ITIKDGAQALIKIGKSVSALHELAEAQGQAVLLVLSGGEGQYNGGMDEVRGESDQRSFEMGREYTDGDGDGMPDADDNVV
DAEYVEEPRAIEHQPLKEELDAAYEEGHKAASEGKPQSDCPVMAGALCIEWVKGWKDWHDEHPQEDPLYVDVEAFVVAEQ
RVSISMVQRHFKIGYNRAARLIERLEANGVVSAMDADGQRKVLKSTEEQEG

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=58, Percent_Identity=53.448275862069, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 32207; Mature: 32076

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPEFKATMNMTANTLGKDLLSVLVQEIKLMPDTWVKLSEKKQNDIIDRLRSRVDASV
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
KMAVHLIAANGRTVVQGDLDKITIKDGAQALIKIGKSVSALHELAEAQGQAVLLVLSGGE
HHHEEEEECCCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GQYNGGMDEVRGESDQRSFEMGREYTDGDGDGMPDADDNVVDAEYVEEPRAIEHQPLKEE
CCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHH
LDAAYEEGHKAASEGKPQSDCPVMAGALCIEWVKGWKDWHDEHPQEDPLYVDVEAFVVAE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
QRVSISMVQRHFKIGYNRAARLIERLEANGVVSAMDADGQRKVLKSTEEQEG
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSPEFKATMNMTANTLGKDLLSVLVQEIKLMPDTWVKLSEKKQNDIIDRLRSRVDASV
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
KMAVHLIAANGRTVVQGDLDKITIKDGAQALIKIGKSVSALHELAEAQGQAVLLVLSGGE
HHHEEEEECCCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GQYNGGMDEVRGESDQRSFEMGREYTDGDGDGMPDADDNVVDAEYVEEPRAIEHQPLKEE
CCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHH
LDAAYEEGHKAASEGKPQSDCPVMAGALCIEWVKGWKDWHDEHPQEDPLYVDVEAFVVAE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
QRVSISMVQRHFKIGYNRAARLIERLEANGVVSAMDADGQRKVLKSTEEQEG
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]