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The map label for this gene is pncB [H]

Identifier: 73541971

GI number: 73541971

Start: 2517821

End: 2518999

Strand: Reverse

Name: pncB [H]

Synonym: Reut_A2284

Alternate gene names: 73541971

Gene position: 2518999-2517821 (Counterclockwise)

Preceding gene: 73541972

Following gene: 73541970

Centisome position: 66.18

GC content: 62.26

Gene sequence:

>1179_bases
ATGATCATCCAATCCCTGCTCGACACCGACCTGTACAAGTTCACGATGATGCAGGTGGTGCTGCACCATTTCCCGCAGGC
CCAGGTCGAGTACCGCTTCAAGTGCCGGAACGCGGATGTTGACCTGACTCCGTATGTCGACGAGATCCGCGCGGAAGTGG
CCCACCTGTGCAGCCTTCGCTTCTCGGATGACGAACTTGCCTACCTGCGTAGCATGCGCTTCATCAAGAGCGATTTCGTC
GATTTCCTCGCGCTGTTCCACCTGAACGAGAAATACGTGTCGATCGAGCCGGCGCCGCAGGGCAATGGTGAAATCGAGAT
TGCGATCCGCGGCTCGTGGCTGCACACGATCCTGTTCGAGGTGCCGCTGCTGGCCATCGTCAACGAGGTTTATTTCCGGG
CCACCCAGCCGCAGCCGGACTTCGCCGAGGGGCGTCGCCGGCTGGAACAGAAGCTGACGCTGCTGCGGGCGCCGAAGTAC
CGCGACTGCGTGATTGCCGACTATGGCACGCGCCGGCGCTTCTCGCGCGACTGGCAGGAGGAAATCCTGCTGGCGACACG
CAAGACGCTGGGGGCGCAACTGGCCGGCACCAGCAACGTGCTTTTTGCATACCGGCACAATATGGTGCCGCTGGGGACCA
TGGCCCATGAGTACCTGCAGGCGTGCCAGGCACTGGGTCCGCGCCTGCGCGACTCACAGGTATTCGCGCTGGAGAACTGG
GCGCGCGAATACCGTGGCGACCTGGGCATCGCGCTGTCGGACACCTACGGCTTCGACGCGTTCCTGCGGGACTTCGATCT
GTTTTTCTGCAAGCTGTTCGATGGCGTTCGGCATGATTCCGGTGACCCGTTCCTGTGGGGCGAGAAGATGCTCGCGCACT
ACGCGGCCAATCGTGTCGATCCGCTCGGCAAGACGCTGATCTTCAGCGACAGCCTCGATATCCCGCGCGTGATCGAGCTG
TACGAGCGGTTCCATGGCCGCTGCAAGCTGGCATTCGGCGTCGGCACCAACCTGACCAACGACCTCGGCTACACGCCGTT
GCAGATCGTCATCAAGATGGTCCGCTGCAACGGCCAGCCGGTGGCCAAGCTGTCGGATACCCCGGAAAAGACCATGTGCG
ACGACCCCGGCTACCTGGCCTACCTGCGTCAGGTATTCGACGTTAAGGCGTCCGCGTAG

Upstream 100 bases:

>100_bases
TCTCGATGGCGGCTGAACTGCCATCCTGGCGCACGCCCGCCGGCAAGCGCGGACTTCGGTTAGCATGTGTGCCTGAACCG
GCATCGCCGTCTGGCCCGTT

Downstream 100 bases:

>100_bases
CCATTTTCAGCGGCTCGGAGAGACGGGCGCGGTAGGGTGCGTCTCTATAATGGCGTGCATCGCACCGCATTTTCTGAACC
TGTCCAAGCCATATGGAAAC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIIQSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNADVDLTPYVDEIRAEVAHLCSLRFSDDELAYLRSMRFIKSDFV
DFLALFHLNEKYVSIEPAPQGNGEIEIAIRGSWLHTILFEVPLLAIVNEVYFRATQPQPDFAEGRRRLEQKLTLLRAPKY
RDCVIADYGTRRRFSRDWQEEILLATRKTLGAQLAGTSNVLFAYRHNMVPLGTMAHEYLQACQALGPRLRDSQVFALENW
AREYRGDLGIALSDTYGFDAFLRDFDLFFCKLFDGVRHDSGDPFLWGEKMLAHYAANRVDPLGKTLIFSDSLDIPRVIEL
YERFHGRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLAYLRQVFDVKASA

Sequences:

>Translated_392_residues
MIIQSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNADVDLTPYVDEIRAEVAHLCSLRFSDDELAYLRSMRFIKSDFV
DFLALFHLNEKYVSIEPAPQGNGEIEIAIRGSWLHTILFEVPLLAIVNEVYFRATQPQPDFAEGRRRLEQKLTLLRAPKY
RDCVIADYGTRRRFSRDWQEEILLATRKTLGAQLAGTSNVLFAYRHNMVPLGTMAHEYLQACQALGPRLRDSQVFALENW
AREYRGDLGIALSDTYGFDAFLRDFDLFFCKLFDGVRHDSGDPFLWGEKMLAHYAANRVDPLGKTLIFSDSLDIPRVIEL
YERFHGRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLAYLRQVFDVKASA
>Mature_392_residues
MIIQSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNADVDLTPYVDEIRAEVAHLCSLRFSDDELAYLRSMRFIKSDFV
DFLALFHLNEKYVSIEPAPQGNGEIEIAIRGSWLHTILFEVPLLAIVNEVYFRATQPQPDFAEGRRRLEQKLTLLRAPKY
RDCVIADYGTRRRFSRDWQEEILLATRKTLGAQLAGTSNVLFAYRHNMVPLGTMAHEYLQACQALGPRLRDSQVFALENW
AREYRGDLGIALSDTYGFDAFLRDFDLFFCKLFDGVRHDSGDPFLWGEKMLAHYAANRVDPLGKTLIFSDSLDIPRVIEL
YERFHGRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLAYLRQVFDVKASA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=392, Percent_Identity=44.8979591836735, Blast_Score=333, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6324783, Length=401, Percent_Identity=31.1720698254364, Blast_Score=200, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45069; Mature: 45069

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIQSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNADVDLTPYVDEIRAEVAHLCSLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
FSDDELAYLRSMRFIKSDFVDFLALFHLNEKYVSIEPAPQGNGEIEIAIRGSWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
VPLLAIVNEVYFRATQPQPDFAEGRRRLEQKLTLLRAPKYRDCVIADYGTRRRFSRDWQE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
EILLATRKTLGAQLAGTSNVLFAYRHNMVPLGTMAHEYLQACQALGPRLRDSQVFALENW
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
AREYRGDLGIALSDTYGFDAFLRDFDLFFCKLFDGVRHDSGDPFLWGEKMLAHYAANRVD
HHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
PLGKTLIFSDSLDIPRVIELYERFHGRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQP
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
VAKLSDTPEKTMCDDPGYLAYLRQVFDVKASA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIQSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNADVDLTPYVDEIRAEVAHLCSLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
FSDDELAYLRSMRFIKSDFVDFLALFHLNEKYVSIEPAPQGNGEIEIAIRGSWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
VPLLAIVNEVYFRATQPQPDFAEGRRRLEQKLTLLRAPKYRDCVIADYGTRRRFSRDWQE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
EILLATRKTLGAQLAGTSNVLFAYRHNMVPLGTMAHEYLQACQALGPRLRDSQVFALENW
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
AREYRGDLGIALSDTYGFDAFLRDFDLFFCKLFDGVRHDSGDPFLWGEKMLAHYAANRVD
HHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
PLGKTLIFSDSLDIPRVIELYERFHGRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQP
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
VAKLSDTPEKTMCDDPGYLAYLRQVFDVKASA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA