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The map label for this gene is efp [H]

Identifier: 73541933

GI number: 73541933

Start: 2479946

End: 2480506

Strand: Direct

Name: efp [H]

Synonym: Reut_A2246

Alternate gene names: 73541933

Gene position: 2479946-2480506 (Clockwise)

Preceding gene: 73541932

Following gene: 73541956

Centisome position: 65.15

GC content: 58.29

Gene sequence:

>561_bases
ATGAAAATCGCACAGGAACTCCGCGTCGGCAACGTGTTCATGATGAACGGCGCTCCGATGGTTGTGCAAAAGGCCGAGTA
CAACAAGTCGGGCCGCAACGCCGCCGTGGTCAAGATGAAGTACAAGAACCTGCTCACCGAAGCCCCGGGCGAGTCGGTGT
TCAAGGCTGACGACAAGTTCGAAGTCGTGGTGCTCGAGCGCCGCGAATGCACCTACTCGTACTTCGCCGACCCGATGTAC
GTGTTCATGGACGCCGACTACAACCAGTTTGAAGTTGAGCAGGACAGCATGGGCGACGCCCTGAACTACCTCGAAGACGG
CATGGCCGTCGAAGTGGTGTTCTACAACGAGAAGGCCATCTCGGTCGAAATGCCGACCACGCTGGTCCGCGAGATTGTCT
ACACCGAACCGGCTGTCAAGGGCGACACCTCGTCGGGCAAGGTGCTGAAGGGCGCCAAGATCAACACCGGCTTCGAACTG
CAAGTGCCGCTGTTCTGCAACATCGGCGACAAGATCGAAATCGACACGCGTACCGGCGAATATCGCAGCCGCGCCAACTA
A

Upstream 100 bases:

>100_bases
CACCAGGCGCTGCCGGTAGCGACAGGCTGCCTGCACGGCGCCTCCGCCATACCTCGCCATACCAATTTCCGAGACTTTCT
TTTTCAGGAAAACAGTTCAG

Downstream 100 bases:

>100_bases
GCGCACGGCTCGCTCCGCCTCCGTGGCGGAGCCGGTGATGAAAAAAGGCAGCCGCGGCTGCCTTTTTTGTCGTCTGGCGC
AAACCCGTCGCGCGCTCAGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKFEVVVLERRECTYSYFADPMY
VFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAISVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFEL
QVPLFCNIGDKIEIDTRTGEYRSRAN

Sequences:

>Translated_186_residues
MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKFEVVVLERRECTYSYFADPMY
VFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAISVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFEL
QVPLFCNIGDKIEIDTRTGEYRSRAN
>Mature_186_residues
MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKFEVVVLERRECTYSYFADPMY
VFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAISVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFEL
QVPLFCNIGDKIEIDTRTGEYRSRAN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=35.1648351648352, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI87082061, Length=191, Percent_Identity=32.9842931937173, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20968; Mature: 20968

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKF
CCCHHHCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCEEECCCCE
EVVVLERRECTYSYFADPMYVFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAI
EEEEEECCCCCEEECCCEEEEEEECCCCEEEECCHHHHHHHHHHCCCCEEEEEEECCEEE
SVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFELQVPLFCNIGDKIEIDTRTGE
EEECCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCCEEEEECCCCC
YRSRAN
CCCCCC
>Mature Secondary Structure
MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKF
CCCHHHCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCEEECCCCE
EVVVLERRECTYSYFADPMYVFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAI
EEEEEECCCCCEEECCCEEEEEEECCCCEEEECCHHHHHHHHHHCCCCEEEEEEECCEEE
SVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFELQVPLFCNIGDKIEIDTRTGE
EEECCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCCEEEEECCCCC
YRSRAN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA