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The map label for this gene is virS [H]

Identifier: 73541837

GI number: 73541837

Start: 2370708

End: 2371805

Strand: Direct

Name: virS [H]

Synonym: Reut_A2149

Alternate gene names: 73541837

Gene position: 2370708-2371805 (Clockwise)

Preceding gene: 73541833

Following gene: 73541841

Centisome position: 62.28

GC content: 65.85

Gene sequence:

>1098_bases
ATGGGACAAAGCAGGCGCAACGCAACGGCGCGCGCTGCACAAAGAACGAGATGGAGACATGCCTTGGACACACTGGTGCG
CGCGGGCGCGCTGACCAATTTCTTTGAAGTCGCCCGGGACCTGGGTCTCAACCCACAGCCATTGCTGAGCGAGGTCCGTC
TGAGCCGCGCACTGCTCGGCGATCCGGACCAACGCGTGTCGGTCAATGCCTGCGCCAGGCTGCTCGAACGTGCGGCGCAA
GCGGCGAACTGCGAGACCTTCGGCCTGCGCATGGCCGAATCGCGCCAGCTGTCCGACTTCGGCGTGATGAGCCTGCTGAT
CAGCCAGCAGCCGACGCTGCGCGCGGCGCTGGCCACGATCATCCGCTACCGGCACCTGGTCAACGAGTCTCTTGCGATCC
TTCTCGAAGAGACGGGCAAGATCGTCACCATCCGCCAGGAAGTGGTGCTCGATACGCCTTCGCGCCAGGCCAGCGAGCTG
GCGGTCGGCGTGGCGTTCCGCCTGTGCCGCGCGCTGCTTGGGCCGCACTGGCACCCCCTCAATGTCAATTTCACGCACGC
GCCGCCGGCAGACCTTCAGGTCCACCGGCGCCTGTTCGGCTGTCCGATTGAGTTCGAAAGCGAGTTCAACGGGATTTCCT
GTCTCGCGGCGGACCTTGATGCCGCCATCCCGACTGCAGACCCTGGCATGGCTCGCTATGCGCAGCGCTTCGTCGACACG
CTACCGCGCGTCAATGCGCCGTCGATCGGACGCGACGTGCGCAGTGCCGTCTACCTGATGCTGCCCATGGGGCGCGCCAC
TTGCGAAGGTGTGGCTCAAGGCCTCGGCCTGAGCCTGCGCACCATGCAGCGACAGCTTGACGATGCCGGCGAAACCTTTA
CCGACATCCTCAACGAAGTCCGACGCGAGCTGGCGCAGCGCTATGTGGAGAACCCGCAGTATTCCTTGCTGCGCGTGGCC
GAATTACTGGGCTACGGCTCGGCAAGTTCGTTCACGCGGTGGTTCTCCGCCCAGTTCGGCGAAGCGCCGCTGGTCTGGCG
GCGCCGGCATGACAGCCGCGCTCCGCAGGGAGCGCAGCCGGCGCACGGCACGCTGTAA

Upstream 100 bases:

>100_bases
CGCTCATGCAGTGAAATGTAGGTGGTGCCGGAACGCACCGCTTTGCATTGGCTTCCGCCAACTTTGCATTTCATGCCACG
GCCGCCTATCATGCGGCTGC

Downstream 100 bases:

>100_bases
CGCCGGCAGGCGCCGAGCGTCAGCGGCTGGCCTTGGGTGTCACGGAAACAGCCAGCGCTTCGGTGTAGACGGCCTGCACC
TGGTCACCCTTGCGGATGCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MGQSRRNATARAAQRTRWRHALDTLVRAGALTNFFEVARDLGLNPQPLLSEVRLSRALLGDPDQRVSVNACARLLERAAQ
AANCETFGLRMAESRQLSDFGVMSLLISQQPTLRAALATIIRYRHLVNESLAILLEETGKIVTIRQEVVLDTPSRQASEL
AVGVAFRLCRALLGPHWHPLNVNFTHAPPADLQVHRRLFGCPIEFESEFNGISCLAADLDAAIPTADPGMARYAQRFVDT
LPRVNAPSIGRDVRSAVYLMLPMGRATCEGVAQGLGLSLRTMQRQLDDAGETFTDILNEVRRELAQRYVENPQYSLLRVA
ELLGYGSASSFTRWFSAQFGEAPLVWRRRHDSRAPQGAQPAHGTL

Sequences:

>Translated_365_residues
MGQSRRNATARAAQRTRWRHALDTLVRAGALTNFFEVARDLGLNPQPLLSEVRLSRALLGDPDQRVSVNACARLLERAAQ
AANCETFGLRMAESRQLSDFGVMSLLISQQPTLRAALATIIRYRHLVNESLAILLEETGKIVTIRQEVVLDTPSRQASEL
AVGVAFRLCRALLGPHWHPLNVNFTHAPPADLQVHRRLFGCPIEFESEFNGISCLAADLDAAIPTADPGMARYAQRFVDT
LPRVNAPSIGRDVRSAVYLMLPMGRATCEGVAQGLGLSLRTMQRQLDDAGETFTDILNEVRRELAQRYVENPQYSLLRVA
ELLGYGSASSFTRWFSAQFGEAPLVWRRRHDSRAPQGAQPAHGTL
>Mature_364_residues
GQSRRNATARAAQRTRWRHALDTLVRAGALTNFFEVARDLGLNPQPLLSEVRLSRALLGDPDQRVSVNACARLLERAAQA
ANCETFGLRMAESRQLSDFGVMSLLISQQPTLRAALATIIRYRHLVNESLAILLEETGKIVTIRQEVVLDTPSRQASELA
VGVAFRLCRALLGPHWHPLNVNFTHAPPADLQVHRRLFGCPIEFESEFNGISCLAADLDAAIPTADPGMARYAQRFVDTL
PRVNAPSIGRDVRSAVYLMLPMGRATCEGVAQGLGLSLRTMQRQLDDAGETFTDILNEVRRELAQRYVENPQYSLLRVAE
LLGYGSASSFTRWFSAQFGEAPLVWRRRHDSRAPQGAQPAHGTL

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 40432; Mature: 40301

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQSRRNATARAAQRTRWRHALDTLVRAGALTNFFEVARDLGLNPQPLLSEVRLSRALLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
DPDQRVSVNACARLLERAAQAANCETFGLRMAESRQLSDFGVMSLLISQQPTLRAALATI
CCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
IRYRHLVNESLAILLEETGKIVTIRQEVVLDTPSRQASELAVGVAFRLCRALLGPHWHPL
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NVNFTHAPPADLQVHRRLFGCPIEFESEFNGISCLAADLDAAIPTADPGMARYAQRFVDT
CEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LPRVNAPSIGRDVRSAVYLMLPMGRATCEGVAQGLGLSLRTMQRQLDDAGETFTDILNEV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RRELAQRYVENPQYSLLRVAELLGYGSASSFTRWFSAQFGEAPLVWRRRHDSRAPQGAQP
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCC
AHGTL
CCCCC
>Mature Secondary Structure 
GQSRRNATARAAQRTRWRHALDTLVRAGALTNFFEVARDLGLNPQPLLSEVRLSRALLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
DPDQRVSVNACARLLERAAQAANCETFGLRMAESRQLSDFGVMSLLISQQPTLRAALATI
CCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
IRYRHLVNESLAILLEETGKIVTIRQEVVLDTPSRQASELAVGVAFRLCRALLGPHWHPL
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NVNFTHAPPADLQVHRRLFGCPIEFESEFNGISCLAADLDAAIPTADPGMARYAQRFVDT
CEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LPRVNAPSIGRDVRSAVYLMLPMGRATCEGVAQGLGLSLRTMQRQLDDAGETFTDILNEV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RRELAQRYVENPQYSLLRVAELLGYGSASSFTRWFSAQFGEAPLVWRRRHDSRAPQGAQP
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCC
AHGTL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]