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The map label for this gene is tauD [H]

Identifier: 73541835

GI number: 73541835

Start: 2368727

End: 2369575

Strand: Reverse

Name: tauD [H]

Synonym: Reut_A2147

Alternate gene names: 73541835

Gene position: 2369575-2368727 (Counterclockwise)

Preceding gene: 73541836

Following gene: 73541834

Centisome position: 62.25

GC content: 64.08

Gene sequence:

>849_bases
ATGCAAGTCAAGCAAATCACCTGCTCGCTGGGTGCGGAACTGGTCGGCGTGAACCTCGCTGACGCCGTCAGGGACGATGG
CCTGTTCGCGGAAATCCGCGCATTGCTGCTGCAGCACCGCGTGCTGTTCCTGCGCGACCAGAACATCAGCCGTGCCGATC
ACGTCGCGTTCGCGCGCCGTTTCGGTGAACTCGAAGACCACCCCGTTGCCGGCAGCGATCCGGAGCACCCGGGTCTGGTT
CGCATCTACAAGACGCCCGACCAGCCCAACGACCGCTACGAGAACGCGTGGCACTCTGACACCACGTGGCGCGAGGCGCC
GCAGTTCGGTGCCGTGCTGCGCTGCGTGGAATGTCCGCCGGTAGGCGGCGACACCATGTGGGCGAACATGGCGCTGGCCT
ATGAGCGCCTGCCCGAACACATCAAGGCACAGATTGCCGACTTGCGCGCCCGCCACAGCATCGAGGCAAGCTTTGGCGCA
GCCATGCCGATCGAAAAGCGCCTGGCCCTGAAGGCACAGTATCCCGATGCCGAGCACCCGGTGGTGCGCACGCATCCGGA
GACCGGCGAGAAGATCCTTTACGTGAACGCGTTCACGACGCATTTCACCAATTTCCATACGGCCAATCGCGTGCGTTTCG
GCCAGGACGCGAACCCGGGCGCGCCCGACCTGCTGCGCTACCTGATCAGCCAGGCGTATATCCCCGAGTACCAGGTGCGC
TGGCGCTGGGAACCCAACAGCATGGCAATTTGGGACAACACCGCCACGCAGCACTACGCCGTGATGGATTACCCGCCTTG
CCACCGCAAGATGGAGCGTGCCGGCATCATCGGCAGCAAGCCGTACTGA

Upstream 100 bases:

>100_bases
ACCAGCGCTATGCCCTGGAGGACGCGGTGCAAGCCCATCGGGACCTGGAGTCGCGCAAGACCACCGGTTCGTCGATCTTT
GTCATCTGAGGGAGCGCGTC

Downstream 100 bases:

>100_bases
CCGAACGCCAGAGGAAAACAATATGCAGCAAAACCTGATCGTATCGACGCCCTCGGCGTACTCGTATCCGCTGCTGGTCA
AGCAGCTGCTGATTCACTCG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQVKQITCSLGAELVGVNLADAVRDDGLFAEIRALLLQHRVLFLRDQNISRADHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKTPDQPNDRYENAWHSDTTWREAPQFGAVLRCVECPPVGGDTMWANMALAYERLPEHIKAQIADLRARHSIEASFGA
AMPIEKRLALKAQYPDAEHPVVRTHPETGEKILYVNAFTTHFTNFHTANRVRFGQDANPGAPDLLRYLISQAYIPEYQVR
WRWEPNSMAIWDNTATQHYAVMDYPPCHRKMERAGIIGSKPY

Sequences:

>Translated_282_residues
MQVKQITCSLGAELVGVNLADAVRDDGLFAEIRALLLQHRVLFLRDQNISRADHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKTPDQPNDRYENAWHSDTTWREAPQFGAVLRCVECPPVGGDTMWANMALAYERLPEHIKAQIADLRARHSIEASFGA
AMPIEKRLALKAQYPDAEHPVVRTHPETGEKILYVNAFTTHFTNFHTANRVRFGQDANPGAPDLLRYLISQAYIPEYQVR
WRWEPNSMAIWDNTATQHYAVMDYPPCHRKMERAGIIGSKPY
>Mature_282_residues
MQVKQITCSLGAELVGVNLADAVRDDGLFAEIRALLLQHRVLFLRDQNISRADHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKTPDQPNDRYENAWHSDTTWREAPQFGAVLRCVECPPVGGDTMWANMALAYERLPEHIKAQIADLRARHSIEASFGA
AMPIEKRLALKAQYPDAEHPVVRTHPETGEKILYVNAFTTHFTNFHTANRVRFGQDANPGAPDLLRYLISQAYIPEYQVR
WRWEPNSMAIWDNTATQHYAVMDYPPCHRKMERAGIIGSKPY

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=289, Percent_Identity=36.3321799307958, Blast_Score=176, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6322971, Length=294, Percent_Identity=29.9319727891156, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 32095; Mature: 32095

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKQITCSLGAELVGVNLADAVRDDGLFAEIRALLLQHRVLFLRDQNISRADHVAFARR
CCHHEEEHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKTPDQPNDRYENAWHSDTTWREAPQFGAVLRCVECPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCHHHCHHHHHHEEEEECCC
VGGDTMWANMALAYERLPEHIKAQIADLRARHSIEASFGAAMPIEKRLALKAQYPDAEHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCC
VVRTHPETGEKILYVNAFTTHFTNFHTANRVRFGQDANPGAPDLLRYLISQAYIPEYQVR
EEEECCCCCCEEEEEEEHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEE
WRWEPNSMAIWDNTATQHYAVMDYPPCHRKMERAGIIGSKPY
EEECCCCEEEECCCCCCEEEEECCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQVKQITCSLGAELVGVNLADAVRDDGLFAEIRALLLQHRVLFLRDQNISRADHVAFARR
CCHHEEEHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKTPDQPNDRYENAWHSDTTWREAPQFGAVLRCVECPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCHHHCHHHHHHEEEEECCC
VGGDTMWANMALAYERLPEHIKAQIADLRARHSIEASFGAAMPIEKRLALKAQYPDAEHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCC
VVRTHPETGEKILYVNAFTTHFTNFHTANRVRFGQDANPGAPDLLRYLISQAYIPEYQVR
EEEECCCCCCEEEEEEEHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCEEE
WRWEPNSMAIWDNTATQHYAVMDYPPCHRKMERAGIIGSKPY
EEECCCCEEEECCCCCCEEEEECCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]