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The map label for this gene is fadE25 [H]

Identifier: 73541828

GI number: 73541828

Start: 2359750

End: 2361552

Strand: Reverse

Name: fadE25 [H]

Synonym: Reut_A2140

Alternate gene names: 73541828

Gene position: 2361552-2359750 (Counterclockwise)

Preceding gene: 73541829

Following gene: 73541827

Centisome position: 62.04

GC content: 65.78

Gene sequence:

>1803_bases
ATGAGCTATACCGCGCCCACCAAGGACATGCTGTTCGCCATGCGCGAACTGGCCGGACTGACAAAGATTGCCACGCTGCC
CGGCTACGAAGACGCCACCCCCGAGACGGTCGAGGCCGTGTTGGAGGAAGCTGCGAAATTCCACGGCGAGGTGCTGGCTC
CGCTGAACGCTGCCGGCGACCGGCAGCCCAGCAACTGGCACGATGGCCAGGTCACCACCACCGCGGGCTTCCGCGATGCC
TTCCGCCAGTTCGGCGAAGGCGGCTGGCAGGGAATCGTCCATCCGGCCGAGTTTGGCGGCCAGGGCCTGCCCAAGCTGGT
GGCGACGCCGTGCATCGAGATGATGAACGCGGCCAATATGTCGTTCGCGCTGTGCCCGCTGCTGACCGATGGCGCCATCG
AAGCGCTGCTCACGGCGGGCTCGGACGAACTCAAGCAGCGTTACCTGCCGCGTCTGATCGCCGGCGAGTGGACCGGCACC
ATGAACCTCACCGAGCCGCAGGCCGGCTCGGACCTGGCACTGGTGCGCAGCCGCGCCGAGCGTCAGGCGGACGGTTCCTA
CAAGGTGTCCGGCACCAAGATCTTCATCACCTACGGCGAGCACGATATGGCGGAGAACATCGTGCACCTGGTGCTGGCGC
GCACGCCGGACGCGCCCGAAGGCGTGAAGGGCATCTCGCTGTTCCTGGTGCCGAAGTTCCTGGTCAACGACGACGGTTCG
CTGGGCGCGCGCAACGACGTCGAGTGCGTGTCGATCGAGCACAAGCTCGGCATCAAGGCGAGCCCGACCGCGGTGCTGCA
GTTCGGCGACAACGGCGGTGCCATCGGCTACCTGATCGGTGAAGAGAACCGTGGCCTCGAGTACATGTTCGTGATGATGA
ACGCTGCGCGCTTCGGCGTAGGCGTGCAGGGCATCGCCATCTCGGACCGCGCCTATCAGCAGGCTGTCGCCTATGCGAAG
GAGCGCGTGCAGAGCCGCCCGGTGGACGGCTCGTCGAAGGACGCTGTGACGATCATCCAGCATCCCGACGTGCGCCGCAT
GCTGATCGAGATGCGTGCGCTGACGGAAGGCGCACGCGCACTGGCACTGGTGGCGGCGGGCTATTCCGATCTGGCGCACC
AGTCACCGGATGCCGAGACTCGCGCCCACTATGGTGCCGCGTACGAATACCTGGTGCCCGTCATCAAGGGTTGGAGCACC
GAGATGTCGCTGGAGGTGACGAGCCTTGGTGTGCAGGTGCACGGCGGCATGGGCTTCATCGAAGAGACCGGCGCGGCCCA
GCATTACCGCGATGCGCGCATCCTGCCGATCTACGAAGGCACGACGGCGATCCAGGCGAATGACCTGATCGGCCGCAAGA
CCATGCGCGACGGCGGCGCGGCAGCGCAAGCCGTCCTCGCGGACATCGACAAGACGCTCGAGGCACTCAAGGAATACGCC
GACGGCTGCCGCAACGGCGCGTGCAGCGCCATGCTCATGCGCCTTGGTGTTGCACGTCTGGCACTCGGCAATGCGGTGGA
TCACGTAGTCGAAAAGGGCCGCAAGGACCCGAATGCGGTGTTCGGCGCCAGCGTTGCCTATCTCAAGCTGACTGGCATCG
TGCTGACGGGCTGGCAAATGGCGCGGGCGCTGGTCGTCGCCATGCAGAAACGCGGTGAAGACGAAGCGTTCTACGGCGCA
AAGATCGCGACGGCCGAGTTCTTCGCCAACCACGTCCTGCCGCGCGCCTCGGCGTTCGAAGCAGCCGTCATCAGCACGAC
TGGCCAGGACGGGTTCCTGGGTCTGGACGAAGCCTGCTTCTGA

Upstream 100 bases:

>100_bases
TTTCGCGTTGATGACCCTTACGATCAGGACCATCAATGATGTCGCAGCGCCGCAGGGCATGAAGCCGGAGCCGACGCTGC
ATCTCCGCGAAAGGAATGAG

Downstream 100 bases:

>100_bases
CGCAGCGCTCGGCACACAAGATCAGGAAGGAATAAAGATGGCAATCGAAGGCTACAACATGGCCACGCTCGGCGCGTTCG
TTGGCAAGGAACTCGGCGTA

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSYTAPTKDMLFAMRELAGLTKIATLPGYEDATPETVEAVLEEAAKFHGEVLAPLNAAGDRQPSNWHDGQVTTTAGFRDA
FRQFGEGGWQGIVHPAEFGGQGLPKLVATPCIEMMNAANMSFALCPLLTDGAIEALLTAGSDELKQRYLPRLIAGEWTGT
MNLTEPQAGSDLALVRSRAERQADGSYKVSGTKIFITYGEHDMAENIVHLVLARTPDAPEGVKGISLFLVPKFLVNDDGS
LGARNDVECVSIEHKLGIKASPTAVLQFGDNGGAIGYLIGEENRGLEYMFVMMNAARFGVGVQGIAISDRAYQQAVAYAK
ERVQSRPVDGSSKDAVTIIQHPDVRRMLIEMRALTEGARALALVAAGYSDLAHQSPDAETRAHYGAAYEYLVPVIKGWST
EMSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLIGRKTMRDGGAAAQAVLADIDKTLEALKEYA
DGCRNGACSAMLMRLGVARLALGNAVDHVVEKGRKDPNAVFGASVAYLKLTGIVLTGWQMARALVVAMQKRGEDEAFYGA
KIATAEFFANHVLPRASAFEAAVISTTGQDGFLGLDEACF

Sequences:

>Translated_600_residues
MSYTAPTKDMLFAMRELAGLTKIATLPGYEDATPETVEAVLEEAAKFHGEVLAPLNAAGDRQPSNWHDGQVTTTAGFRDA
FRQFGEGGWQGIVHPAEFGGQGLPKLVATPCIEMMNAANMSFALCPLLTDGAIEALLTAGSDELKQRYLPRLIAGEWTGT
MNLTEPQAGSDLALVRSRAERQADGSYKVSGTKIFITYGEHDMAENIVHLVLARTPDAPEGVKGISLFLVPKFLVNDDGS
LGARNDVECVSIEHKLGIKASPTAVLQFGDNGGAIGYLIGEENRGLEYMFVMMNAARFGVGVQGIAISDRAYQQAVAYAK
ERVQSRPVDGSSKDAVTIIQHPDVRRMLIEMRALTEGARALALVAAGYSDLAHQSPDAETRAHYGAAYEYLVPVIKGWST
EMSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLIGRKTMRDGGAAAQAVLADIDKTLEALKEYA
DGCRNGACSAMLMRLGVARLALGNAVDHVVEKGRKDPNAVFGASVAYLKLTGIVLTGWQMARALVVAMQKRGEDEAFYGA
KIATAEFFANHVLPRASAFEAAVISTTGQDGFLGLDEACF
>Mature_599_residues
SYTAPTKDMLFAMRELAGLTKIATLPGYEDATPETVEAVLEEAAKFHGEVLAPLNAAGDRQPSNWHDGQVTTTAGFRDAF
RQFGEGGWQGIVHPAEFGGQGLPKLVATPCIEMMNAANMSFALCPLLTDGAIEALLTAGSDELKQRYLPRLIAGEWTGTM
NLTEPQAGSDLALVRSRAERQADGSYKVSGTKIFITYGEHDMAENIVHLVLARTPDAPEGVKGISLFLVPKFLVNDDGSL
GARNDVECVSIEHKLGIKASPTAVLQFGDNGGAIGYLIGEENRGLEYMFVMMNAARFGVGVQGIAISDRAYQQAVAYAKE
RVQSRPVDGSSKDAVTIIQHPDVRRMLIEMRALTEGARALALVAAGYSDLAHQSPDAETRAHYGAAYEYLVPVIKGWSTE
MSLEVTSLGVQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLIGRKTMRDGGAAAQAVLADIDKTLEALKEYAD
GCRNGACSAMLMRLGVARLALGNAVDHVVEKGRKDPNAVFGASVAYLKLTGIVLTGWQMARALVVAMQKRGEDEAFYGAK
IATAEFFANHVLPRASAFEAAVISTTGQDGFLGLDEACF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=27.4151436031332, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI4557233, Length=413, Percent_Identity=29.0556900726392, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4501859, Length=410, Percent_Identity=27.0731707317073, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=416, Percent_Identity=26.4423076923077, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=26.3020833333333, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=26.3020833333333, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226958412, Length=410, Percent_Identity=25.3658536585366, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226958414, Length=378, Percent_Identity=24.8677248677249, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=24.3455497382199, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI187960098, Length=316, Percent_Identity=25.9493670886076, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557231, Length=316, Percent_Identity=25.9493670886076, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503943, Length=315, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082384, Length=344, Percent_Identity=28.7790697674419, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=23.6503856041131, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=408, Percent_Identity=28.1862745098039, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=28.8828337874659, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=383, Percent_Identity=28.4595300261097, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI86563381, Length=343, Percent_Identity=30.3206997084548, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=343, Percent_Identity=30.3206997084548, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=408, Percent_Identity=27.4509803921569, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=422, Percent_Identity=26.303317535545, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=28.0653950953678, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=424, Percent_Identity=25, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=353, Percent_Identity=25.4957507082153, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=26.9129287598945, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=24.7956403269755, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=26.5957446808511, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=257, Percent_Identity=31.1284046692607, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=29.3617021276596, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=299, Percent_Identity=23.7458193979933, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=29.5212765957447, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363737, Length=369, Percent_Identity=28.4552845528455, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355753, Length=425, Percent_Identity=26.8235294117647, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=27.7929155313352, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=26.4864864864865, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24660351, Length=361, Percent_Identity=26.8698060941828, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920834, Length=324, Percent_Identity=26.2345679012346, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 64215; Mature: 64084

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTAPTKDMLFAMRELAGLTKIATLPGYEDATPETVEAVLEEAAKFHGEVLAPLNAAGD
CCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCC
RQPSNWHDGQVTTTAGFRDAFRQFGEGGWQGIVHPAEFGGQGLPKLVATPCIEMMNAANM
CCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSDELKQRYLPRLIAGEWTGTMNLTEPQAGSDLALVRSRAE
CEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RQADGSYKVSGTKIFITYGEHDMAENIVHLVLARTPDAPEGVKGISLFLVPKFLVNDDGS
HCCCCCEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHEECCCCC
LGARNDVECVSIEHKLGIKASPTAVLQFGDNGGAIGYLIGEENRGLEYMFVMMNAARFGV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEHHHHHHCC
GVQGIAISDRAYQQAVAYAKERVQSRPVDGSSKDAVTIIQHPDVRRMLIEMRALTEGARA
CEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHE
LALVAAGYSDLAHQSPDAETRAHYGAAYEYLVPVIKGWSTEMSLEVTSLGVQVHGGMGFI
EHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLIGRKTMRDGGAAAQAVLADIDKTLEALKEYA
HHCCCHHHHCCCEEEEEECCCCEEEECCHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGCRNGACSAMLMRLGVARLALGNAVDHVVEKGRKDPNAVFGASVAYLKLTGIVLTGWQM
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEEHHHEEHHHH
ARALVVAMQKRGEDEAFYGAKIATAEFFANHVLPRASAFEAAVISTTGQDGFLGLDEACF
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHCC
>Mature Secondary Structure 
SYTAPTKDMLFAMRELAGLTKIATLPGYEDATPETVEAVLEEAAKFHGEVLAPLNAAGD
CCCCCHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCC
RQPSNWHDGQVTTTAGFRDAFRQFGEGGWQGIVHPAEFGGQGLPKLVATPCIEMMNAANM
CCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSDELKQRYLPRLIAGEWTGTMNLTEPQAGSDLALVRSRAE
CEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RQADGSYKVSGTKIFITYGEHDMAENIVHLVLARTPDAPEGVKGISLFLVPKFLVNDDGS
HCCCCCEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHEECCCCC
LGARNDVECVSIEHKLGIKASPTAVLQFGDNGGAIGYLIGEENRGLEYMFVMMNAARFGV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEHHHHHHCC
GVQGIAISDRAYQQAVAYAKERVQSRPVDGSSKDAVTIIQHPDVRRMLIEMRALTEGARA
CEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHE
LALVAAGYSDLAHQSPDAETRAHYGAAYEYLVPVIKGWSTEMSLEVTSLGVQVHGGMGFI
EHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQHYRDARILPIYEGTTAIQANDLIGRKTMRDGGAAAQAVLADIDKTLEALKEYA
HHCCCHHHHCCCEEEEEECCCCEEEECCHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGCRNGACSAMLMRLGVARLALGNAVDHVVEKGRKDPNAVFGASVAYLKLTGIVLTGWQM
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEEHHHEEHHHH
ARALVVAMQKRGEDEAFYGAKIATAEFFANHVLPRASAFEAAVISTTGQDGFLGLDEACF
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]