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The map label for this gene is yybO [H]

Identifier: 73541820

GI number: 73541820

Start: 2351960

End: 2353282

Strand: Direct

Name: yybO [H]

Synonym: Reut_A2132

Alternate gene names: 73541820

Gene position: 2351960-2353282 (Clockwise)

Preceding gene: 73541818

Following gene: 73541821

Centisome position: 61.79

GC content: 67.42

Gene sequence:

>1323_bases
ATGCTTGGACATTCTTCCACTCAACCCGCCATGGTGACCGGCACGCAAACCGTGGCCGCATCCCGCTTCTATCCATGGCT
GGTTTTCGCGCTCAGCTTTGGCCTGCTGCTGTCGGACTACATGTCGCGCCAGGTGCTCAACGCAGTATTCCCGTTGCTGA
AAGCGGAATGGGCACTCTCCGACACCGAACTCGGCGCCCTGGGTGGCATCGTGGCGCTGATGGTCGGCCTGCTGACGTTT
CCGCTGTCGATCCTTGCCGACCGCTGGGGCCGCGTCAAAAGCCTGACGCTGATGGCCGCGCTCTGGAGCGTGGCGACGCT
AGGCTGCGCGCTGGCCAACAACTTCGGCGAAATGTTCATCGCCCGCCTGTGCGTCGGCATCGGCGAAGCGGCCTACGGCA
GCGTGGGCATCGCCGTGGTGCTGTCGGTGTTTCCGCGCCACCTGCGCGCCAGCCTGAGTTCGGCCTTCATCGCTGGCGGC
GCGTTCGGCTCCGTGCTTGGCATGGCTGCAGGCGGCACGCTGTCGGCCCAGTTCGGCTGGCGCTGGGCGTTCGCCGGCAT
GGCCATCTTCGGGCTGGTACTCGTGGTGATCTATCGTGCGCTGATCACGGAGCCGCGCCTGCAGGCACAGCGCCGCGCAT
TGGGCGAAGACGCGGCACCTGAAGTGCAGCGCGAGAGCATGACCATTCGTCCGCTGCTGTCGGCCCTGTTCTCCGCGCGG
TCCATCCTTTGCGCCTACGTAGGCAGCGCCCTGCAACTGCTCGTGATGGGCGCACTGCTCGCGTGGATGCCCAGCTTCCT
GTCGCGCTACTACGGTATGGCTACGGACCGTGCAGGCATTACCGCTGCGGCGTTCGTCCTGGCCGCCGGTGCGGGCATGG
TGGTGTGCGGCGCGCTGACCGACTGGGTCGCCCGTCATTCCCCGTCGCGCAAGTGGCTGATGGCCATCGGCTACAGCGTC
ACCTGCTGCGTGCTGCTGGCTGTGGCGTTCCGGCTGCCGGCCGGTACGGCGCAGCTTGCGCTGATCGGTGCAGGCATGCT
GCTGGTCGGCGGCACGGCTGGTCCCGCCAGCGCCGTTGTGGCCAATCTGACTCGTCCCGCTATCCACGCGACCGCGTTTG
CCACGCTCACGCTGGCCAACAACCTGCTGGGCCTGGCCCCGGGCCCGTTCGTCACCGGTGTGCTTGCCGACCGCATCGGC
TTGCTTGGCGCGCTGCAGTGGATTCCGCTGACCGGCCTGCTCGCCGCAGTGTGCTTCATCGCCGGCCGCCGCTACTACAC
GGCGGATCTGGAGCGCCTGGAGCGCCAGCGCGGCGCAAAGTAA

Upstream 100 bases:

>100_bases
CCGATACTTCGCCAGTCGCTTCCGAGACCATGTCACGGTCCCGGGCCGCCCGATACCGGCATGACCAAAAGGGCGTTCAA
GATTCTCAGGAGAAGCATTC

Downstream 100 bases:

>100_bases
ACCACTACCTGACCTACTGGAATTCTGGAACTCCAATGAGCCTTACTACTGACACCACCGTCCTGCTGGTTCCCGGCCTG
CGCGACCACGTCGCCGAGCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MLGHSSTQPAMVTGTQTVAASRFYPWLVFALSFGLLLSDYMSRQVLNAVFPLLKAEWALSDTELGALGGIVALMVGLLTF
PLSILADRWGRVKSLTLMAALWSVATLGCALANNFGEMFIARLCVGIGEAAYGSVGIAVVLSVFPRHLRASLSSAFIAGG
AFGSVLGMAAGGTLSAQFGWRWAFAGMAIFGLVLVVIYRALITEPRLQAQRRALGEDAAPEVQRESMTIRPLLSALFSAR
SILCAYVGSALQLLVMGALLAWMPSFLSRYYGMATDRAGITAAAFVLAAGAGMVVCGALTDWVARHSPSRKWLMAIGYSV
TCCVLLAVAFRLPAGTAQLALIGAGMLLVGGTAGPASAVVANLTRPAIHATAFATLTLANNLLGLAPGPFVTGVLADRIG
LLGALQWIPLTGLLAAVCFIAGRRYYTADLERLERQRGAK

Sequences:

>Translated_440_residues
MLGHSSTQPAMVTGTQTVAASRFYPWLVFALSFGLLLSDYMSRQVLNAVFPLLKAEWALSDTELGALGGIVALMVGLLTF
PLSILADRWGRVKSLTLMAALWSVATLGCALANNFGEMFIARLCVGIGEAAYGSVGIAVVLSVFPRHLRASLSSAFIAGG
AFGSVLGMAAGGTLSAQFGWRWAFAGMAIFGLVLVVIYRALITEPRLQAQRRALGEDAAPEVQRESMTIRPLLSALFSAR
SILCAYVGSALQLLVMGALLAWMPSFLSRYYGMATDRAGITAAAFVLAAGAGMVVCGALTDWVARHSPSRKWLMAIGYSV
TCCVLLAVAFRLPAGTAQLALIGAGMLLVGGTAGPASAVVANLTRPAIHATAFATLTLANNLLGLAPGPFVTGVLADRIG
LLGALQWIPLTGLLAAVCFIAGRRYYTADLERLERQRGAK
>Mature_440_residues
MLGHSSTQPAMVTGTQTVAASRFYPWLVFALSFGLLLSDYMSRQVLNAVFPLLKAEWALSDTELGALGGIVALMVGLLTF
PLSILADRWGRVKSLTLMAALWSVATLGCALANNFGEMFIARLCVGIGEAAYGSVGIAVVLSVFPRHLRASLSSAFIAGG
AFGSVLGMAAGGTLSAQFGWRWAFAGMAIFGLVLVVIYRALITEPRLQAQRRALGEDAAPEVQRESMTIRPLLSALFSAR
SILCAYVGSALQLLVMGALLAWMPSFLSRYYGMATDRAGITAAAFVLAAGAGMVVCGALTDWVARHSPSRKWLMAIGYSV
TCCVLLAVAFRLPAGTAQLALIGAGMLLVGGTAGPASAVVANLTRPAIHATAFATLTLANNLLGLAPGPFVTGVLADRIG
LLGALQWIPLTGLLAAVCFIAGRRYYTADLERLERQRGAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=440, Percent_Identity=23.4090909090909, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367379, Length=271, Percent_Identity=26.5682656826568, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=22.0183486238532, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082320, Length=398, Percent_Identity=23.3668341708543, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539092, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17557872, Length=402, Percent_Identity=23.6318407960199, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193209775, Length=407, Percent_Identity=22.1130221130221, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654039, Length=376, Percent_Identity=24.7340425531915, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864456, Length=376, Percent_Identity=24.7340425531915, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654044, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654037, Length=238, Percent_Identity=27.7310924369748, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654041, Length=238, Percent_Identity=27.7310924369748, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46135; Mature: 46135

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGHSSTQPAMVTGTQTVAASRFYPWLVFALSFGLLLSDYMSRQVLNAVFPLLKAEWALS
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTELGALGGIVALMVGLLTFPLSILADRWGRVKSLTLMAALWSVATLGCALANNFGEMFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLCVGIGEAAYGSVGIAVVLSVFPRHLRASLSSAFIAGGAFGSVLGMAAGGTLSAQFGW
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCCH
RWAFAGMAIFGLVLVVIYRALITEPRLQAQRRALGEDAAPEVQRESMTIRPLLSALFSAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHH
SILCAYVGSALQLLVMGALLAWMPSFLSRYYGMATDRAGITAAAFVLAAGAGMVVCGALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
DWVARHSPSRKWLMAIGYSVTCCVLLAVAFRLPAGTAQLALIGAGMLLVGGTAGPASAVV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHEECCCCCHHHHHH
ANLTRPAIHATAFATLTLANNLLGLAPGPFVTGVLADRIGLLGALQWIPLTGLLAAVCFI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRRYYTADLERLERQRGAK
HCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLGHSSTQPAMVTGTQTVAASRFYPWLVFALSFGLLLSDYMSRQVLNAVFPLLKAEWALS
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTELGALGGIVALMVGLLTFPLSILADRWGRVKSLTLMAALWSVATLGCALANNFGEMFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLCVGIGEAAYGSVGIAVVLSVFPRHLRASLSSAFIAGGAFGSVLGMAAGGTLSAQFGW
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCCH
RWAFAGMAIFGLVLVVIYRALITEPRLQAQRRALGEDAAPEVQRESMTIRPLLSALFSAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHH
SILCAYVGSALQLLVMGALLAWMPSFLSRYYGMATDRAGITAAAFVLAAGAGMVVCGALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
DWVARHSPSRKWLMAIGYSVTCCVLLAVAFRLPAGTAQLALIGAGMLLVGGTAGPASAVV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHEECCCCCHHHHHH
ANLTRPAIHATAFATLTLANNLLGLAPGPFVTGVLADRIGLLGALQWIPLTGLLAAVCFI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRRYYTADLERLERQRGAK
HCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]