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The map label for this gene is dapL [H]

Identifier: 73541580

GI number: 73541580

Start: 2074585

End: 2075784

Strand: Direct

Name: dapL [H]

Synonym: Reut_A1891

Alternate gene names: 73541580

Gene position: 2074585-2075784 (Clockwise)

Preceding gene: 73541578

Following gene: 73541581

Centisome position: 54.5

GC content: 65.75

Gene sequence:

>1200_bases
GTGAATCCGCGCCTCGACCTGCTCCAGCCCTACCCCTTCGAGAAACTGCGCGTGCTGTTCGCGGAGGTGAAACCGGCCGA
CAAGCCGGCAATCAGTTTCGGCATCGGCGAACCCAAGCACCCCACGCCTGAATTCATCAAGAAGGCGCTGGCCGAGTCGC
TGGCGGGGCTGGCGAATTATCCCACAACGGCTGGTTCCGATGCACTACGACAGTGCATCGCCACCTGGCTGGAGCGCCGC
TACGGCCTGCCGAAGGTCAATGCGGCGACCGAAGTGCTGCCAGTGACGGGCTCGCGCGAAGCGCTGTTCGCCTTCGCGCA
GACCGTGGTCGATGGCACGCGCTCCGGCGCGCTGGTGCTGTGTCCGAACCCGTTCTATCAAATTTATGAAGGTGCCGCGC
TGCTGGCGGGTGCCACGCCAGTGTTCGCGAACAGCGACCCGGCGCGCAACTTCGCCCCGGCGTTCGACCGCATTGCCGAC
GATGTCTGGAAAAATGTCCAGCTCCTCTTCGTCTGCTCGCCGGGCAACCCGACCGGCGCTGTGCTGTCGCTGGAAGACTG
GAAGCAACTGTTCGCGCTCTCGGACAAGTACGGCTTCGTAATCGCCTCAGACGAGTGCTACTCCGAGATCTACTTCGATG
AGAGCCGCGCGCCGCTCGGTGCGCTGGAGGCCGCCCACAAGCTCGGCCGCGGCTTCGAGCGGCTGGTGATGTTCTCGAGC
CTGTCCAAGCGCTCCAACGTCCCGGGCCTGCGCTCCGGCTTCGTCGCCGGCGATGCCGCGCTGCTCAAGAAATTCCTGCT
ATACCGTACCTACCACGGCGGCGCGATGAACCCGGCCGTGCAGACGGCCAGCATTGCGGCCTGGAACGACGAAGCCCACG
TGCGCGAGAACCGCGCCGCCTACGTGCGCAAGTTCAGCGAAGTGACGCCGATGCTGGCCGAGGTGCTGGACGTGGCGCTG
CCCGATGCCGGTTTCTACCTGTGGGCCGATGTTTCGCGCACGGGCCTGAATGATGTCGAGTTCGCCGCGCAGCTGCTGGC
GGCGCAGAACGTCACCGTGCTGCCGGGCAGCTACCTGGCGCGCGAAGCCGATGGCATCAACCCGGGCGCCAACCGTGTGC
GCATGGCACTGGTCGCCACGCCGGAGGAATGCCTGGAAGGCGCGCGGCGCATTGTGGAATTCTGCAAGTCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CGGCATCCGCACACCAGATGCGCCGCGCGGGCCGCGCCAATGCGCGGGATACCGTGCCGTTCCTTTATAATGCTGGGTTT
CAACCGGCCCCATCCAGAAC

Downstream 100 bases:

>100_bases
TCCATCGGATCGAACGAACTCCCGTGGCGCGGCCCGACCGCCGCGCCTTCTCCAAACAACCACTGAAGAAACGCAAATGA
CGCAAGCTCTGCAAGCCCTG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNPRLDLLQPYPFEKLRVLFAEVKPADKPAISFGIGEPKHPTPEFIKKALAESLAGLANYPTTAGSDALRQCIATWLERR
YGLPKVNAATEVLPVTGSREALFAFAQTVVDGTRSGALVLCPNPFYQIYEGAALLAGATPVFANSDPARNFAPAFDRIAD
DVWKNVQLLFVCSPGNPTGAVLSLEDWKQLFALSDKYGFVIASDECYSEIYFDESRAPLGALEAAHKLGRGFERLVMFSS
LSKRSNVPGLRSGFVAGDAALLKKFLLYRTYHGGAMNPAVQTASIAAWNDEAHVRENRAAYVRKFSEVTPMLAEVLDVAL
PDAGFYLWADVSRTGLNDVEFAAQLLAAQNVTVLPGSYLAREADGINPGANRVRMALVATPEECLEGARRIVEFCKSLG

Sequences:

>Translated_399_residues
MNPRLDLLQPYPFEKLRVLFAEVKPADKPAISFGIGEPKHPTPEFIKKALAESLAGLANYPTTAGSDALRQCIATWLERR
YGLPKVNAATEVLPVTGSREALFAFAQTVVDGTRSGALVLCPNPFYQIYEGAALLAGATPVFANSDPARNFAPAFDRIAD
DVWKNVQLLFVCSPGNPTGAVLSLEDWKQLFALSDKYGFVIASDECYSEIYFDESRAPLGALEAAHKLGRGFERLVMFSS
LSKRSNVPGLRSGFVAGDAALLKKFLLYRTYHGGAMNPAVQTASIAAWNDEAHVRENRAAYVRKFSEVTPMLAEVLDVAL
PDAGFYLWADVSRTGLNDVEFAAQLLAAQNVTVLPGSYLAREADGINPGANRVRMALVATPEECLEGARRIVEFCKSLG
>Mature_399_residues
MNPRLDLLQPYPFEKLRVLFAEVKPADKPAISFGIGEPKHPTPEFIKKALAESLAGLANYPTTAGSDALRQCIATWLERR
YGLPKVNAATEVLPVTGSREALFAFAQTVVDGTRSGALVLCPNPFYQIYEGAALLAGATPVFANSDPARNFAPAFDRIAD
DVWKNVQLLFVCSPGNPTGAVLSLEDWKQLFALSDKYGFVIASDECYSEIYFDESRAPLGALEAAHKLGRGFERLVMFSS
LSKRSNVPGLRSGFVAGDAALLKKFLLYRTYHGGAMNPAVQTASIAAWNDEAHVRENRAAYVRKFSEVTPMLAEVLDVAL
PDAGFYLWADVSRTGLNDVEFAAQLLAAQNVTVLPGSYLAREADGINPGANRVRMALVATPEECLEGARRIVEFCKSLG

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=333, Percent_Identity=23.4234234234234, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI169881279, Length=333, Percent_Identity=23.4234234234234, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI56713256, Length=331, Percent_Identity=24.4712990936556, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI56713254, Length=331, Percent_Identity=24.4712990936556, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1788722, Length=406, Percent_Identity=27.0935960591133, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786816, Length=332, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=401, Percent_Identity=24.9376558603491, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=420, Percent_Identity=23.3333333333333, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=408, Percent_Identity=23.2843137254902, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=408, Percent_Identity=23.2843137254902, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=168, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323118, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43343; Mature: 43343

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRLDLLQPYPFEKLRVLFAEVKPADKPAISFGIGEPKHPTPEFIKKALAESLAGLANY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PTTAGSDALRQCIATWLERRYGLPKVNAATEVLPVTGSREALFAFAQTVVDGTRSGALVL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
CPNPFYQIYEGAALLAGATPVFANSDPARNFAPAFDRIADDVWKNVQLLFVCSPGNPTGA
CCCHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
VLSLEDWKQLFALSDKYGFVIASDECYSEIYFDESRAPLGALEAAHKLGRGFERLVMFSS
EEEHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSKRSNVPGLRSGFVAGDAALLKKFLLYRTYHGGAMNPAVQTASIAAWNDEAHVRENRAA
HHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEECCCHHHHHHHHH
YVRKFSEVTPMLAEVLDVALPDAGFYLWADVSRTGLNDVEFAAQLLAAQNVTVLPGSYLA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCHHHH
READGINPGANRVRMALVATPEECLEGARRIVEFCKSLG
HHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPRLDLLQPYPFEKLRVLFAEVKPADKPAISFGIGEPKHPTPEFIKKALAESLAGLANY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PTTAGSDALRQCIATWLERRYGLPKVNAATEVLPVTGSREALFAFAQTVVDGTRSGALVL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
CPNPFYQIYEGAALLAGATPVFANSDPARNFAPAFDRIADDVWKNVQLLFVCSPGNPTGA
CCCHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
VLSLEDWKQLFALSDKYGFVIASDECYSEIYFDESRAPLGALEAAHKLGRGFERLVMFSS
EEEHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSKRSNVPGLRSGFVAGDAALLKKFLLYRTYHGGAMNPAVQTASIAAWNDEAHVRENRAA
HHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEECCCHHHHHHHHH
YVRKFSEVTPMLAEVLDVALPDAGFYLWADVSRTGLNDVEFAAQLLAAQNVTVLPGSYLA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCHHHH
READGINPGANRVRMALVATPEECLEGARRIVEFCKSLG
HHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA