Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 73541423

GI number: 73541423

Start: 1873980

End: 1874753

Strand: Direct

Name: degU [H]

Synonym: Reut_A1734

Alternate gene names: 73541423

Gene position: 1873980-1874753 (Clockwise)

Preceding gene: 73541400

Following gene: 73541431

Centisome position: 49.23

GC content: 64.34

Gene sequence:

>774_bases
ATGTCAGTTTTCTGCCTGCGGCGTGGACGGCAAAAGTGTGGCTCGCCCGTCAACCCTCATTTCCAAATGAATCCAACAAT
TACCAACAAGAAGCCTGCGCTGACGGGGAACCTCTTGCTGGTCGGTCACGAAAAGCGTATGCGCGCCCGCCTTTGCGCGA
TCCTCTCGGATCTCGACTACACGGCAGACGCACTCACCTACACCTGCTGCCCCGAGGAAGCCCATGCCCAGCTGGTCGAG
CGCCCGTTCGACATGGTCCTGGTCGACAGCAGCCTGGCCCACGGCAATGGCATCGACCTGATCGGCGCGCTGCATGCGCG
CGATCCGCGCATGCCGATCGTGGTGATCTCCGATCCAGCCGCCGAAGCCGACGTAATGAGTGCCTTGCGCGCCGGAGCAA
GCGGCTACCTGCTCAAGGAGCGCGACGACACTGAACTCTCGGTCTCTCTGCGCAGTGCCCTGCGCGGCGGCATGCCGATC
GATCCGTTCATCGCCAGGCAAGTATTGCGGTCGCTCGTGCCTGCCGACCCGCACGCCGCCTGCAGCCCGCCGGCCGGCTG
CGCGGGGCCCGAGGCCAGGAGCCCGCTGAGCACGCGCGAACTGGAGATTCTGCGCTGCATCGACCGCGGCGCGACCAACC
GCGAAATCGCCGCCGCGCTGTCGCTGTCCACGTTGACCATCGAATCGCACGTCAAGAACATCCACAAGAAGCTGGGCGTC
AAGACGCGTACCCAGGCCACCTTTGAAGCGCGCCGGTATGGGCTGCTAAACTAA

Upstream 100 bases:

>100_bases
GTAATCCGGTATTTTCTACAGTTCGCGCAAAGTTGCCAGAAACGCGAAAGTCGATGGCATCGAATTGCTCATTTTTGGGT
ATTCTGAGAGCGATGCATTT

Downstream 100 bases:

>100_bases
GACGCCATTCTGAAAATTCGCTGCAGATGAGTTCCGGCAATGCCGCCTCGCACGCTGTGTTCACTTTGCGTGGCAAGCTG
GGCATTACGTATGGGAGGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSVFCLRRGRQKCGSPVNPHFQMNPTITNKKPALTGNLLLVGHEKRMRARLCAILSDLDYTADALTYTCCPEEAHAQLVE
RPFDMVLVDSSLAHGNGIDLIGALHARDPRMPIVVISDPAAEADVMSALRAGASGYLLKERDDTELSVSLRSALRGGMPI
DPFIARQVLRSLVPADPHAACSPPAGCAGPEARSPLSTRELEILRCIDRGATNREIAAALSLSTLTIESHVKNIHKKLGV
KTRTQATFEARRYGLLN

Sequences:

>Translated_257_residues
MSVFCLRRGRQKCGSPVNPHFQMNPTITNKKPALTGNLLLVGHEKRMRARLCAILSDLDYTADALTYTCCPEEAHAQLVE
RPFDMVLVDSSLAHGNGIDLIGALHARDPRMPIVVISDPAAEADVMSALRAGASGYLLKERDDTELSVSLRSALRGGMPI
DPFIARQVLRSLVPADPHAACSPPAGCAGPEARSPLSTRELEILRCIDRGATNREIAAALSLSTLTIESHVKNIHKKLGV
KTRTQATFEARRYGLLN
>Mature_256_residues
SVFCLRRGRQKCGSPVNPHFQMNPTITNKKPALTGNLLLVGHEKRMRARLCAILSDLDYTADALTYTCCPEEAHAQLVER
PFDMVLVDSSLAHGNGIDLIGALHARDPRMPIVVISDPAAEADVMSALRAGASGYLLKERDDTELSVSLRSALRGGMPID
PFIARQVLRSLVPADPHAACSPPAGCAGPEARSPLSTRELEILRCIDRGATNREIAAALSLSTLTIESHVKNIHKKLGVK
TRTQATFEARRYGLLN

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=166, Percent_Identity=28.9156626506024, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788222, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27883; Mature: 27751

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFCLRRGRQKCGSPVNPHFQMNPTITNKKPALTGNLLLVGHEKRMRARLCAILSDLDY
CCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEECCEEEEECHHHHHHHHHHHHHHCCC
TADALTYTCCPEEAHAQLVERPFDMVLVDSSLAHGNGIDLIGALHARDPRMPIVVISDPA
CHHHEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEECCC
AEADVMSALRAGASGYLLKERDDTELSVSLRSALRGGMPIDPFIARQVLRSLVPADPHAA
CHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
CSPPAGCAGPEARSPLSTRELEILRCIDRGATNREIAAALSLSTLTIESHVKNIHKKLGV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTRTQATFEARRYGLLN
CCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVFCLRRGRQKCGSPVNPHFQMNPTITNKKPALTGNLLLVGHEKRMRARLCAILSDLDY
CCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEECCEEEEECHHHHHHHHHHHHHHCCC
TADALTYTCCPEEAHAQLVERPFDMVLVDSSLAHGNGIDLIGALHARDPRMPIVVISDPA
CHHHEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEECCC
AEADVMSALRAGASGYLLKERDDTELSVSLRSALRGGMPIDPFIARQVLRSLVPADPHAA
CHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
CSPPAGCAGPEARSPLSTRELEILRCIDRGATNREIAAALSLSTLTIESHVKNIHKKLGV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTRTQATFEARRYGLLN
CCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]