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The map label for this gene is blaA [H]

Identifier: 73541373

GI number: 73541373

Start: 1816944

End: 1817882

Strand: Direct

Name: blaA [H]

Synonym: Reut_A1684

Alternate gene names: 73541373

Gene position: 1816944-1817882 (Clockwise)

Preceding gene: 73541372

Following gene: 73541374

Centisome position: 47.73

GC content: 67.09

Gene sequence:

>939_bases
ATGCTGGCGAGCAGGCAGACAGTTAGAATGCCCGGATGGCATTCACCGTCGCTTCCCATGCTCCCTTCAAGAACCCGCCG
CACCTTGCTTTTGGCCGCTGCCGCGGCTCCGTTTGCCTCCGCCTGCGCCAGTTCGGCGCGCTCCACCACGCCTGACGCCG
AATCGAGACTGGCCACGCTGGAGCGCAGTGCCGGCGGCCGCCTTGGCGTATTCGCGCGCCACACCGGCGATAGCCGCCAG
GTACGGCATCGCGCCGAGGAGCGCTTCCCGTTTTGCAGCACCTTCAAGGTGATACTCGCCGGCGCTGTCCTGCAGCGCAG
CGCAGGCGCGCCCGGCCTTCTCGATGAGCATGTCCGCTACACGCGCCAGGACCTGGTTGCCTATTCCCCCATTACGGAGA
AGCATGTCGCGGACGGCATGACCATCGCCCAGTTGTGCGCCGCTGCGATCCAGTACAGCGACAACGGCGCCGCTAACCTG
CTGATGCACCGTCTCGGCGGCCCCGCTGCCGTGACCGGATTCGCGCGCTCCATCGGCGACCAGACCTTCCGGCTCGACCG
CTGGGAAACCGAACTGAATACCGCGATTCCCGGCGATCCGCGCGATACTTCAACGCCTGCCGCCATGGCAGCCAGCCTGC
AGGCGCTGGCGCTCGACGGCGCCTTGCCCCCAGTACAGCGCAATCAATTGCAGGCATGGCTGCGCGGCAATACGACCGGC
GCAGCGCGCATCCAGGCAGGAATGCCCGCCGGCTGGCAGATCGGCGACAAGACCGGCAGCGGCGACTATGGCACGACCAA
CGACATCGCCGTGTTGTGGCCCCTGGCGGGCGCGCCGATCGTGGTTGCTATCTATTTCACGCAAGCCGCCCCGGATGCGA
AGTGGAGCAATGAAACGATCGCCAGCGCGGCGCGCATCGCGCTCTCCGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
GCCATCCAGCGGCAGCTGCCGGTGGATCCACGCACGCGTGGTGGACCATGGGCTGCCGTGGGGCGAGACCAGGCGGAGGA
CATGCAGGCGGCAAACGTAA

Downstream 100 bases:

>100_bases
AATCGTCAGGCAGTTGGTTGCACATACGGCGTAGAGTCGGCAAGTGCGCCGACCTACGGATACATCACTTTTTCCGTCAT
CTTTCAAGGTCATGCTTCAG

Product: Beta-lactamase

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLASRQTVRMPGWHSPSLPMLPSRTRRTLLLAAAAAPFASACASSARSTTPDAESRLATLERSAGGRLGVFARHTGDSRQ
VRHRAEERFPFCSTFKVILAGAVLQRSAGAPGLLDEHVRYTRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANL
LMHRLGGPAAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRNQLQAWLRGNTTG
AARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQAAPDAKWSNETIASAARIALSALG

Sequences:

>Translated_312_residues
MLASRQTVRMPGWHSPSLPMLPSRTRRTLLLAAAAAPFASACASSARSTTPDAESRLATLERSAGGRLGVFARHTGDSRQ
VRHRAEERFPFCSTFKVILAGAVLQRSAGAPGLLDEHVRYTRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANL
LMHRLGGPAAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRNQLQAWLRGNTTG
AARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQAAPDAKWSNETIASAARIALSALG
>Mature_312_residues
MLASRQTVRMPGWHSPSLPMLPSRTRRTLLLAAAAAPFASACASSARSTTPDAESRLATLERSAGGRLGVFARHTGDSRQ
VRHRAEERFPFCSTFKVILAGAVLQRSAGAPGLLDEHVRYTRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANL
LMHRLGGPAAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRNQLQAWLRGNTTG
AARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQAAPDAKWSNETIASAARIALSALG

Specific function: Unknown

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32969; Mature: 32969

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASRQTVRMPGWHSPSLPMLPSRTRRTLLLAAAAAPFASACASSARSTTPDAESRLATL
CCCCCCEEECCCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ERSAGGRLGVFARHTGDSRQVRHRAEERFPFCSTFKVILAGAVLQRSAGAPGLLDEHVRY
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGPAAVTGFARSIGD
HHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCC
QTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRNQLQAWLRGNTTG
CCEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
AARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQAAPDAKWSNETI
CEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCHHH
ASAARIALSALG
HHHHHHHHHHCC
>Mature Secondary Structure
MLASRQTVRMPGWHSPSLPMLPSRTRRTLLLAAAAAPFASACASSARSTTPDAESRLATL
CCCCCCEEECCCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ERSAGGRLGVFARHTGDSRQVRHRAEERFPFCSTFKVILAGAVLQRSAGAPGLLDEHVRY
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGPAAVTGFARSIGD
HHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCC
QTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRNQLQAWLRGNTTG
CCEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
AARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQAAPDAKWSNETI
CEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCHHH
ASAARIALSALG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1886608 [H]