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The map label for this gene is hipA [C]

Identifier: 73541319

GI number: 73541319

Start: 1751687

End: 1753018

Strand: Direct

Name: hipA [C]

Synonym: Reut_A1629

Alternate gene names: 73541319

Gene position: 1751687-1753018 (Clockwise)

Preceding gene: 73541318

Following gene: 73541320

Centisome position: 46.02

GC content: 61.04

Gene sequence:

>1332_bases
ATGAGCTTTGAACTGCACCCCCGGTACCTGGAGGTTCACCTTCATGGGCGGCTCTGCGGCTTCCTTTGTGAAGCGGGTGG
GAATACCCGCTTCGTTCCCACGGACGAATACCGGGGCGACAACGAGCGTTACACGCTCAGCTTGTCCATTACTCTGCCAA
CAGAGATTGGCCGGGAAGCCACGTCGGCAGTGTTCGACAACGCGTTCCACCCCGCGATCTACAACACGGGCGGCGAGCTT
CCCCCGTACTTTGCCGGGTTGCTGCCGGAGGGCGAACTGCGCAAGCGCCTTGAGTCCACCCGAACGAATCCTGAGGACAA
GGACGATTTTGGCGTTCTGGCCTCCGCTGGCAACGATTTGCCGGGCGCCATCGTTGTGAAGCCGGCCGATGTCCGCGCAC
TGCCGGGATACGTGCGCACCTACGGCGTGACGGGCGGCGCTGACAACCTCGAGATCGCGGTAGTCGAAGGCGCGACGGAA
GGCGCGGCGTCGGTTTCGGGTGTCCAGAACAAGCTGGCGCTTTCGACGATGCGCAAGGGCGAGCGGTACACCCTCCCGAC
TAAGGGGAAGGTATCCGACATCATCGCCAAGCTGCCGGCGAAGAATGACGATTCCCAGGTGTTCAACGAATACGTGTCGA
TGCATCTTGCAGCGGCGGCCGGAGTGAACATCGCCCCGATCCAGGTTCTTCCCATGTCGAGTATCGACGTGCCGGACCTG
GCAGATTTGATGGGAAAGGGCTTGCATTACCTGGCGGTGGAGCGCTTTGATCGCGCCGCCGACGGTGGCCTTCTCCATGC
GGAGGACGGCTGTCAAATGCTCGGCCGGATGCCCAACAGGAAGTACGCAAAGCGTGAAGAGTACATTCGGCTACTGGCGG
CACTGTACCGGCTCAGCCCGAAGGGATTTGAGAACGTACGACAGTTCTTCTTGCGCCAGGCAGTCAATACGCTGATCGGC
AATAGCGACGCGCATCTGAAGAACTTCTCGGTGATCTACCGCGACCGGAAGCTGCCGGAGCTCTCGCCGGCGTACGACAT
CGTGTGCGTCGCTGCCTTGCCCAACTTCACGTCCTATGGTCAGAACGTTGCGATTGACGAGATCCAGCGCAAGGAGACCA
TGGATCTTTATGAAGATATCGCGGACAAGGCCGGCATCCCCAGGCGGATCGCTACAGCCGCGGTCAAGGAGGCCGTGTCC
ATGGCCCACGCGCATTGGCCAGGCCTTCTGGAGAAGATGGGCGCATCGCAAGCGTTGCGCGACGTCATCGCCGAGCGACT
GGAGAATCTACCGTTGGCTAAGGTGGGAAGGCCAACGAGGAAGGGGGCTTGA

Upstream 100 bases:

>100_bases
CCAAGGAGAAGCTGGCTGAGGTACGCCAGGTTCTCGACGGCAAAGGTAGCGGTCCGGATCGCACTGCTCGGTCCACACTG
GATTACCTGGTGAGCAAATA

Downstream 100 bases:

>100_bases
CCGGGCATGCCATGATTTCGACCAGGTGATTGTTGCGTAACGGGAAACCGTCTGTTGCTGAGTTCCCTCTTTGTCGCTTT
CGGGAAAACCCTTATCTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSFELHPRYLEVHLHGRLCGFLCEAGGNTRFVPTDEYRGDNERYTLSLSITLPTEIGREATSAVFDNAFHPAIYNTGGEL
PPYFAGLLPEGELRKRLESTRTNPEDKDDFGVLASAGNDLPGAIVVKPADVRALPGYVRTYGVTGGADNLEIAVVEGATE
GAASVSGVQNKLALSTMRKGERYTLPTKGKVSDIIAKLPAKNDDSQVFNEYVSMHLAAAAGVNIAPIQVLPMSSIDVPDL
ADLMGKGLHYLAVERFDRAADGGLLHAEDGCQMLGRMPNRKYAKREEYIRLLAALYRLSPKGFENVRQFFLRQAVNTLIG
NSDAHLKNFSVIYRDRKLPELSPAYDIVCVAALPNFTSYGQNVAIDEIQRKETMDLYEDIADKAGIPRRIATAAVKEAVS
MAHAHWPGLLEKMGASQALRDVIAERLENLPLAKVGRPTRKGA

Sequences:

>Translated_443_residues
MSFELHPRYLEVHLHGRLCGFLCEAGGNTRFVPTDEYRGDNERYTLSLSITLPTEIGREATSAVFDNAFHPAIYNTGGEL
PPYFAGLLPEGELRKRLESTRTNPEDKDDFGVLASAGNDLPGAIVVKPADVRALPGYVRTYGVTGGADNLEIAVVEGATE
GAASVSGVQNKLALSTMRKGERYTLPTKGKVSDIIAKLPAKNDDSQVFNEYVSMHLAAAAGVNIAPIQVLPMSSIDVPDL
ADLMGKGLHYLAVERFDRAADGGLLHAEDGCQMLGRMPNRKYAKREEYIRLLAALYRLSPKGFENVRQFFLRQAVNTLIG
NSDAHLKNFSVIYRDRKLPELSPAYDIVCVAALPNFTSYGQNVAIDEIQRKETMDLYEDIADKAGIPRRIATAAVKEAVS
MAHAHWPGLLEKMGASQALRDVIAERLENLPLAKVGRPTRKGA
>Mature_442_residues
SFELHPRYLEVHLHGRLCGFLCEAGGNTRFVPTDEYRGDNERYTLSLSITLPTEIGREATSAVFDNAFHPAIYNTGGELP
PYFAGLLPEGELRKRLESTRTNPEDKDDFGVLASAGNDLPGAIVVKPADVRALPGYVRTYGVTGGADNLEIAVVEGATEG
AASVSGVQNKLALSTMRKGERYTLPTKGKVSDIIAKLPAKNDDSQVFNEYVSMHLAAAAGVNIAPIQVLPMSSIDVPDLA
DLMGKGLHYLAVERFDRAADGGLLHAEDGCQMLGRMPNRKYAKREEYIRLLAALYRLSPKGFENVRQFFLRQAVNTLIGN
SDAHLKNFSVIYRDRKLPELSPAYDIVCVAALPNFTSYGQNVAIDEIQRKETMDLYEDIADKAGIPRRIATAAVKEAVSM
AHAHWPGLLEKMGASQALRDVIAERLENLPLAKVGRPTRKGA

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=347, Percent_Identity=26.8011527377522, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 48426; Mature: 48295

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFELHPRYLEVHLHGRLCGFLCEAGGNTRFVPTDEYRGDNERYTLSLSITLPTEIGREA
CCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECHHHCHHH
TSAVFDNAFHPAIYNTGGELPPYFAGLLPEGELRKRLESTRTNPEDKDDFGVLASAGNDL
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
PGAIVVKPADVRALPGYVRTYGVTGGADNLEIAVVEGATEGAASVSGVQNKLALSTMRKG
CCEEEECCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
ERYTLPTKGKVSDIIAKLPAKNDDSQVFNEYVSMHLAAAAGVNIAPIQVLPMSSIDVPDL
CEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
ADLMGKGLHYLAVERFDRAADGGLLHAEDGCQMLGRMPNRKYAKREEYIRLLAALYRLSP
HHHHHCCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGFENVRQFFLRQAVNTLIGNSDAHLKNFSVIYRDRKLPELSPAYDIVCVAALPNFTSYG
CCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCCCCCEEEEEECCCHHHCC
QNVAIDEIQRKETMDLYEDIADKAGIPRRIATAAVKEAVSMAHAHWPGLLEKMGASQALR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHH
DVIAERLENLPLAKVGRPTRKGA
HHHHHHHHCCCCHHCCCCCCCCC
>Mature Secondary Structure 
SFELHPRYLEVHLHGRLCGFLCEAGGNTRFVPTDEYRGDNERYTLSLSITLPTEIGREA
CCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECHHHCHHH
TSAVFDNAFHPAIYNTGGELPPYFAGLLPEGELRKRLESTRTNPEDKDDFGVLASAGNDL
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
PGAIVVKPADVRALPGYVRTYGVTGGADNLEIAVVEGATEGAASVSGVQNKLALSTMRKG
CCEEEECCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
ERYTLPTKGKVSDIIAKLPAKNDDSQVFNEYVSMHLAAAAGVNIAPIQVLPMSSIDVPDL
CEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
ADLMGKGLHYLAVERFDRAADGGLLHAEDGCQMLGRMPNRKYAKREEYIRLLAALYRLSP
HHHHHCCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGFENVRQFFLRQAVNTLIGNSDAHLKNFSVIYRDRKLPELSPAYDIVCVAALPNFTSYG
CCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCCCCCEEEEEECCCHHHCC
QNVAIDEIQRKETMDLYEDIADKAGIPRRIATAAVKEAVSMAHAHWPGLLEKMGASQALR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHH
DVIAERLENLPLAKVGRPTRKGA
HHHHHHHHCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]