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The map label for this gene is virS [H]

Identifier: 73541296

GI number: 73541296

Start: 1728424

End: 1729500

Strand: Direct

Name: virS [H]

Synonym: Reut_A1606

Alternate gene names: 73541296

Gene position: 1728424-1729500 (Clockwise)

Preceding gene: 73541294

Following gene: 73541299

Centisome position: 45.41

GC content: 63.7

Gene sequence:

>1077_bases
ATGTCGCTACTTGTCCGCGCCGCAGCCCTTACCAACTACTGCGAAGTTGCGCGTGCCGGCGGGCTTGATCCGCTACGAAT
GATGTTTGACGCCGGAATCAGTCCGAGCGTACTGCGCGAGCCGGATCTCATGATTCAGGTGGATCGTTTCGGGCGGCTGC
TCCAGACCTCTGCAACGCTGTCAGGCAACGAGAGTTTCGGATTGAGCATGGCCGAGTCGCGCCTGTTGTCCAACCTGGGG
CCGGTAGGCATGCTGATCCGCGACCAGGCGACGCTGCGCGACGCGCTCGGCATGTTGATGCGCTACCAATCGATTCTCAA
CGGCGCGAAGTCGCTGGCAGTCGACGAGTGTGGTGGACGGGTCATCATTCGCGAGGTACTGATCGCCGGCAGCGCGCATC
AGCCAACTCGCCAACGGGTTGAACTGGCGCTGGGGGTCATGGTGCGGCTGATACGCCAGCTCATCAAACCGGACTGGCAG
CCGCAGCGCGTATGCTTCGAGCACCCGGCCCCGCGCGACCTCAGTACGCATCAGCGGTTCTTTGGCCCGAACGTCGCATT
CAATTGCGATTTCAATGGCATCGTCTGCGCAAAGTCCGATCTCGATGCGCGCAACCCGTGGGCCGATCCGGCCATGGCAC
GCTACGCGCAGCGCCTGATCGACGAGTCGGCCGCGGCGCGGCAGACGACCATGCTTGAGGACGTACGGCGCACGATCCTG
CTGTTGTTGCCCGGCGGGCGCTGCAGCGTCGAGCAGGTCGCGGAAAATCTCGGCGTGGTCTGCCGCACGGTCCAGCGCAG
GCTGGCGGAGCAGGGGCAGAGCTTCTCATCGGTCGTCAACGACATCCGCGTGGAACTCGCAATGCGTCATGTCGTCGAGA
GCGATCGACCTTTTACCGAGGTGGCGACGCTGCTCGGCTTTTCTGCGCCAAGCGGATTCTCGCGCTGGTATCAGACGCAG
TTCGGATGCAGCCCCAAGGAAAGCCGCGCTGCAAGTGCCGCGGTGGGCGAACGGGTGACAGAAACCCCATCTCCTGCCCG
CTCGTCGCCCACAGTCAGGCCTCTCAGTCGAGGGTGA

Upstream 100 bases:

>100_bases
ATGGCGTAGTGCCATGACCGGCTTTTCGTGGCGGGTTAGTCCGGCTTGACAATGCATGACCTAGATTTACCATGGACTGT
CATTTTCTGATTAGCCCCCG

Downstream 100 bases:

>100_bases
TCTTTCCCGCCTTGACGATCTGGCCATAGCGCGAAATATCGCGCTCGATCAGTTTGCGGAAATCCTCGGATGTACCGCCC
ACCGGCACGAAGCCGAGGTC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSLLVRAAALTNYCEVARAGGLDPLRMMFDAGISPSVLREPDLMIQVDRFGRLLQTSATLSGNESFGLSMAESRLLSNLG
PVGMLIRDQATLRDALGMLMRYQSILNGAKSLAVDECGGRVIIREVLIAGSAHQPTRQRVELALGVMVRLIRQLIKPDWQ
PQRVCFEHPAPRDLSTHQRFFGPNVAFNCDFNGIVCAKSDLDARNPWADPAMARYAQRLIDESAAARQTTMLEDVRRTIL
LLLPGGRCSVEQVAENLGVVCRTVQRRLAEQGQSFSSVVNDIRVELAMRHVVESDRPFTEVATLLGFSAPSGFSRWYQTQ
FGCSPKESRAASAAVGERVTETPSPARSSPTVRPLSRG

Sequences:

>Translated_358_residues
MSLLVRAAALTNYCEVARAGGLDPLRMMFDAGISPSVLREPDLMIQVDRFGRLLQTSATLSGNESFGLSMAESRLLSNLG
PVGMLIRDQATLRDALGMLMRYQSILNGAKSLAVDECGGRVIIREVLIAGSAHQPTRQRVELALGVMVRLIRQLIKPDWQ
PQRVCFEHPAPRDLSTHQRFFGPNVAFNCDFNGIVCAKSDLDARNPWADPAMARYAQRLIDESAAARQTTMLEDVRRTIL
LLLPGGRCSVEQVAENLGVVCRTVQRRLAEQGQSFSSVVNDIRVELAMRHVVESDRPFTEVATLLGFSAPSGFSRWYQTQ
FGCSPKESRAASAAVGERVTETPSPARSSPTVRPLSRG
>Mature_357_residues
SLLVRAAALTNYCEVARAGGLDPLRMMFDAGISPSVLREPDLMIQVDRFGRLLQTSATLSGNESFGLSMAESRLLSNLGP
VGMLIRDQATLRDALGMLMRYQSILNGAKSLAVDECGGRVIIREVLIAGSAHQPTRQRVELALGVMVRLIRQLIKPDWQP
QRVCFEHPAPRDLSTHQRFFGPNVAFNCDFNGIVCAKSDLDARNPWADPAMARYAQRLIDESAAARQTTMLEDVRRTILL
LLPGGRCSVEQVAENLGVVCRTVQRRLAEQGQSFSSVVNDIRVELAMRHVVESDRPFTEVATLLGFSAPSGFSRWYQTQF
GCSPKESRAASAAVGERVTETPSPARSSPTVRPLSRG

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786758, Length=95, Percent_Identity=33.6842105263158, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39313; Mature: 39182

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVRAAALTNYCEVARAGGLDPLRMMFDAGISPSVLREPDLMIQVDRFGRLLQTSATL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCEEEHHHHHHHHHHHCCC
SGNESFGLSMAESRLLSNLGPVGMLIRDQATLRDALGMLMRYQSILNGAKSLAVDECGGR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIIREVLIAGSAHQPTRQRVELALGVMVRLIRQLIKPDWQPQRVCFEHPAPRDLSTHQRF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHH
FGPNVAFNCDFNGIVCAKSDLDARNPWADPAMARYAQRLIDESAAARQTTMLEDVRRTIL
CCCCCEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LLLPGGRCSVEQVAENLGVVCRTVQRRLAEQGQSFSSVVNDIRVELAMRHVVESDRPFTE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYQTQFGCSPKESRAASAAVGERVTETPSPARSSPTVRPLSRG
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLLVRAAALTNYCEVARAGGLDPLRMMFDAGISPSVLREPDLMIQVDRFGRLLQTSATL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCEEEHHHHHHHHHHHCCC
SGNESFGLSMAESRLLSNLGPVGMLIRDQATLRDALGMLMRYQSILNGAKSLAVDECGGR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIIREVLIAGSAHQPTRQRVELALGVMVRLIRQLIKPDWQPQRVCFEHPAPRDLSTHQRF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHH
FGPNVAFNCDFNGIVCAKSDLDARNPWADPAMARYAQRLIDESAAARQTTMLEDVRRTIL
CCCCCEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LLLPGGRCSVEQVAENLGVVCRTVQRRLAEQGQSFSSVVNDIRVELAMRHVVESDRPFTE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYQTQFGCSPKESRAASAAVGERVTETPSPARSSPTVRPLSRG
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]