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The map label for this gene is arnA [H]

Identifier: 73541029

GI number: 73541029

Start: 1432773

End: 1433840

Strand: Reverse

Name: arnA [H]

Synonym: Reut_A1335

Alternate gene names: 73541029

Gene position: 1433840-1432773 (Counterclockwise)

Preceding gene: 73541030

Following gene: 73541020

Centisome position: 37.67

GC content: 61.61

Gene sequence:

>1068_bases
ATGCAACAACCCAATTCCATGCAAGGCAAGAAAGTCCTCATCCTCGGCGTCAACGGCTTCATCGGCCACCACTTGACGCG
CCGCATCCTGGAAACGACGTCGTGGGAGGTCTACGGCATGGACATGTCGTCCGACCGCCTCGGTGACCTCGTCGACCATC
CGCGCATGCACTTCTTTGAAGGTGACATCACCATCAACAAGGAGTGGATCGAGTACAACATCCGCAAGTGCGACGTGGTG
CTGCCGCTGGTGGCCATCGCCACGCCGGCCACGTACGTGCGTCAGCCGCTGCGTGTGTTCGAGCTCGACTTCGAAGCGAA
CCTGCCGATCGTGCGCGCCGCCGTGAAGTACGGCAAGCACCTGGTGTTCCCGTCGACCTCCGAGGTCTACGGCATGTGCG
CCGACGACGAATTCGATCCCGAGTCGTCGCCGCTGATCTACGGTCCGATCAACAAGCCGCGCTGGATCTACGCCTGCTCC
AAGCAGCTCATGGATCGCGTGATCCATGCCTATGGCATGGAGCAAGGCCTGAACTACACGCTCTTCCGCCCGTTCAACTG
GATCGGTGCGGGACTCGACTCGATCTTCGAATCGAAGGAAGGTTCGTCGCGCGTGGTCACGCAGTTCCTCGGCCACATCG
TGCGCGGCGAGCCGATCAAGCTCGTCGACGGCGGCGAGCAGAAGCGTGCGTTTGCCGATATCTCGGACGGCATCTCGGCG
CTGATGCGCATCATCGAGAACCCGAACGGCATCGCCACGGGCAAGATCTTCAATATCGGCAACCCGTCCAACATCCACTC
GGTGCGCGAGCTCGCCGAGATGATGCTGAAGATGGCCGCCGACTATCCCGAATACGCCGAGGAAGCGCGCAAGACGCAAA
TCGTCGAGACCTCGTCGGGCGACTTCTACGGCAAGGGCTACCAGGACGTGCAGCACCGCGTGCCGAAGATCGACAACACC
ATGCAGGAACTCGGCTGGAAGCCCGAGGTGACGATGGAACAGGCGCTGCGCCGGATCTTCGAGGCGTATCGCGACCACGT
CGTCGACGCCCGCACGCTGGTCAACTAA

Upstream 100 bases:

>100_bases
CGCGGGACTGGCGCCGTGTAGCCGTTACCAACTTCGCCGTGAATCCTCCGGCACCGCAGCGCTGAAGCACCAAGCGCCCG
GCACCCCTTACGCTTAACCC

Downstream 100 bases:

>100_bases
GCGACTAGGCCGAGCGCGGGACTTACACTCCCGCCTTGTCCCTCCCGCGCCATCAACGGCACGGCGCAGGACCTGTCCCG
AGCTGTACAAGGACGTTTTC

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQQPNSMQGKKVLILGVNGFIGHHLTRRILETTSWEVYGMDMSSDRLGDLVDHPRMHFFEGDITINKEWIEYNIRKCDVV
LPLVAIATPATYVRQPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADDEFDPESSPLIYGPINKPRWIYACS
KQLMDRVIHAYGMEQGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGEQKRAFADISDGISA
LMRIIENPNGIATGKIFNIGNPSNIHSVRELAEMMLKMAADYPEYAEEARKTQIVETSSGDFYGKGYQDVQHRVPKIDNT
MQELGWKPEVTMEQALRRIFEAYRDHVVDARTLVN

Sequences:

>Translated_355_residues
MQQPNSMQGKKVLILGVNGFIGHHLTRRILETTSWEVYGMDMSSDRLGDLVDHPRMHFFEGDITINKEWIEYNIRKCDVV
LPLVAIATPATYVRQPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADDEFDPESSPLIYGPINKPRWIYACS
KQLMDRVIHAYGMEQGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGEQKRAFADISDGISA
LMRIIENPNGIATGKIFNIGNPSNIHSVRELAEMMLKMAADYPEYAEEARKTQIVETSSGDFYGKGYQDVQHRVPKIDNT
MQELGWKPEVTMEQALRRIFEAYRDHVVDARTLVN
>Mature_355_residues
MQQPNSMQGKKVLILGVNGFIGHHLTRRILETTSWEVYGMDMSSDRLGDLVDHPRMHFFEGDITINKEWIEYNIRKCDVV
LPLVAIATPATYVRQPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADDEFDPESSPLIYGPINKPRWIYACS
KQLMDRVIHAYGMEQGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGEQKRAFADISDGISA
LMRIIENPNGIATGKIFNIGNPSNIHSVRELAEMMLKMAADYPEYAEEARKTQIVETSSGDFYGKGYQDVQHRVPKIDNT
MQELGWKPEVTMEQALRRIFEAYRDHVVDARTLVN

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=27.6470588235294, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=21.6138328530259, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788589, Length=335, Percent_Identity=56.1194029850746, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17539532, Length=352, Percent_Identity=23.0113636363636, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356223, Length=357, Percent_Identity=24.0896358543417, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 40324; Mature: 40324

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPNSMQGKKVLILGVNGFIGHHLTRRILETTSWEVYGMDMSSDRLGDLVDHPRMHFFE
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCEEEE
GDITINKEWIEYNIRKCDVVLPLVAIATPATYVRQPLRVFELDFEANLPIVRAAVKYGKH
CCEEEEHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCE
LVFPSTSEVYGMCADDEFDPESSPLIYGPINKPRWIYACSKQLMDRVIHAYGMEQGLNYT
EECCCCHHHEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGEQKRAFADISDGISA
EECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
LMRIIENPNGIATGKIFNIGNPSNIHSVRELAEMMLKMAADYPEYAEEARKTQIVETSSG
HHHHHHCCCCEEECEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCC
DFYGKGYQDVQHRVPKIDNTMQELGWKPEVTMEQALRRIFEAYRDHVVDARTLVN
CCCCCCHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQPNSMQGKKVLILGVNGFIGHHLTRRILETTSWEVYGMDMSSDRLGDLVDHPRMHFFE
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCEEEE
GDITINKEWIEYNIRKCDVVLPLVAIATPATYVRQPLRVFELDFEANLPIVRAAVKYGKH
CCEEEEHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCE
LVFPSTSEVYGMCADDEFDPESSPLIYGPINKPRWIYACSKQLMDRVIHAYGMEQGLNYT
EECCCCHHHEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGEQKRAFADISDGISA
EECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
LMRIIENPNGIATGKIFNIGNPSNIHSVRELAEMMLKMAADYPEYAEEARKTQIVETSSG
HHHHHHCCCCEEECEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCC
DFYGKGYQDVQHRVPKIDNTMQELGWKPEVTMEQALRRIFEAYRDHVVDARTLVN
CCCCCCHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA