BacMap

Definition	Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession	NC_007347
Length	3,806,533

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The map label for this gene is fabG [H]

Identifier: 73540890

GI number: 73540890

Start: 1277364

End: 1278083

Strand: Reverse

Name: fabG [H]

Synonym: Reut_A1195

Alternate gene names: 73540890

Gene position: 1278083-1277364 (Counterclockwise)

Preceding gene: 73540891

Following gene: 73540889

Centisome position: 33.58

GC content: 64.58

Gene sequence:

>720_bases
ATGATTCCAGAATCGGTTCTTGTCACCGGAGGCTCCGGCGGTATTGGCTGGGCCTTGTGCCAGACCCTGGCGAGACGCGG
CAGCCATGTCGTGAGCATCGACCGCGCCCTGCCGCCGCAGCCAGGCATCGTGGAATTCTACGAAGCAGACATGGCCAGTG
AAGCCGAACTTGCTGCAGTCCTGCGCGATGCCTGCGGCAAGTATGCATTCGGCGGGCTCGTCAACAATGTCGCCACGCTG
CGCCCCGCCAGCATCGGTGATACGACGCTGGACGACTTCGACAGCCAGATGCTGGTCAACGCCCGCGCCGCCCTGCAATG
CGCACAGGCGGCTCTGCCCGCCATGCGCGCGGCACGACAGGGCCGCATTGTCAACATTTCCAGCCGCGCGGCGCTTGGCA
AGGAAATGCGCACGGCGTACGCCGCGACCAAGGGTGCGCTCAATGCAATGACCCGGACGTGGGCGCTCGAATTAGGCGCG
GATGGCATTACCGTGAATGCGGTCGCGCCCGGGCCAATTGCCACTGCGGCGTTCGGAACGGCCAATCCGGCACAGCAGGC
ACTGACGCAACGGATTGTCGCCGGCGTCCCCGTGAAACGGCTGGGAAACGCCGACGACATCGTCCACGCCGTGGAGTTCT
TCCTGGATACGCGCGCTTCGTTCGTGACAGGGCAGATCCTGCATGTGTGCGGCGGCATTACCGTGGGGTTGTCAGCATGA

Upstream 100 bases:

>100_bases
TGCCCCTGACCGCGAACGGCAAGGTTTCAAAGCAGGCCCTCCGGGATCAACTGGCGAACTCGGACGGCAAGGCCCATTTC
CCCAAGGAGACGCTCGCATC

Downstream 100 bases:

>100_bases
GCAGCACTCACACGAGCATCCGCACTGACATTGGCACCACCACGCCAGACCGCATTTCGGTGCGTGGCCGCGATCTTGCG
CGCGACGTGATTGGCAAGAT

Product: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIPESVLVTGGSGGIGWALCQTLARRGSHVVSIDRALPPQPGIVEFYEADMASEAELAAVLRDACGKYAFGGLVNNVATL
RPASIGDTTLDDFDSQMLVNARAALQCAQAALPAMRAARQGRIVNISSRAALGKEMRTAYAATKGALNAMTRTWALELGA
DGITVNAVAPGPIATAAFGTANPAQQALTQRIVAGVPVKRLGNADDIVHAVEFFLDTRASFVTGQILHVCGGITVGLSA

Sequences:

>Translated_239_residues
MIPESVLVTGGSGGIGWALCQTLARRGSHVVSIDRALPPQPGIVEFYEADMASEAELAAVLRDACGKYAFGGLVNNVATL
RPASIGDTTLDDFDSQMLVNARAALQCAQAALPAMRAARQGRIVNISSRAALGKEMRTAYAATKGALNAMTRTWALELGA
DGITVNAVAPGPIATAAFGTANPAQQALTQRIVAGVPVKRLGNADDIVHAVEFFLDTRASFVTGQILHVCGGITVGLSA
>Mature_239_residues
MIPESVLVTGGSGGIGWALCQTLARRGSHVVSIDRALPPQPGIVEFYEADMASEAELAAVLRDACGKYAFGGLVNNVATL
RPASIGDTTLDDFDSQMLVNARAALQCAQAALPAMRAARQGRIVNISSRAALGKEMRTAYAATKGALNAMTRTWALELGA
DGITVNAVAPGPIATAAFGTANPAQQALTQRIVAGVPVKRLGNADDIVHAVEFFLDTRASFVTGQILHVCGGITVGLSA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.9623430962343, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=31.3008130081301, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=30.9236947791165, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI10190704, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=29.7071129707113, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=29.3650793650794, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=30.4932735426009, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=32.7731092436975, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=28.8537549407115, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=30.8943089430894, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=31.9327731092437, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=26.4822134387352, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=28.099173553719, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=28.968253968254, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788459, Length=165, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=30.6772908366534, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.9180327868852, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.9595141700405, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=31.9796954314721, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=32.0987654320988, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=28.2786885245902, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=31.1475409836066, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=164, Percent_Identity=31.7073170731707, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=29.1187739463602, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=24.4813278008299, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=29.4573643410853, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.8888888888889, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=26.5384615384615, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=27.8810408921933, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=28.2442748091603, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.9961977186312, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=26.3565891472868, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=255, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=27.0161290322581, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=164, Percent_Identity=28.0487804878049, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=33.1932773109244, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI23397609, Length=240, Percent_Identity=29.5833333333333, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=30.8333333333333, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.9795918367347, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.3008130081301, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=30.4878048780488, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=29.3172690763052, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24673; Mature: 24673

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPESVLVTGGSGGIGWALCQTLARRGSHVVSIDRALPPQPGIVEFYEADMASEAELAAV
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHH
LRDACGKYAFGGLVNNVATLRPASIGDTTLDDFDSQMLVNARAALQCAQAALPAMRAARQ
HHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRIVNISSRAALGKEMRTAYAATKGALNAMTRTWALELGADGITVNAVAPGPIATAAFGT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHCCCC
ANPAQQALTQRIVAGVPVKRLGNADDIVHAVEFFLDTRASFVTGQILHVCGGITVGLSA
CCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MIPESVLVTGGSGGIGWALCQTLARRGSHVVSIDRALPPQPGIVEFYEADMASEAELAAV
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHH
LRDACGKYAFGGLVNNVATLRPASIGDTTLDDFDSQMLVNARAALQCAQAALPAMRAARQ
HHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRIVNISSRAALGKEMRTAYAATKGALNAMTRTWALELGADGITVNAVAPGPIATAAFGT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHCCCC
ANPAQQALTQRIVAGVPVKRLGNADDIVHAVEFFLDTRASFVTGQILHVCGGITVGLSA
CCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]