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The map label for this gene is fabG [H]

Identifier: 73540887

GI number: 73540887

Start: 1275098

End: 1275955

Strand: Reverse

Name: fabG [H]

Synonym: Reut_A1192

Alternate gene names: 73540887

Gene position: 1275955-1275098 (Counterclockwise)

Preceding gene: 73540888

Following gene: 73540886

Centisome position: 33.52

GC content: 67.95

Gene sequence:

>858_bases
GTGACTGATTCCCTGCAACTGCGCCCTGATCAACAACTCTTCGCGCCCGCCCTGGGCACCGTTCGGCGCGAGGGTCGGCT
CGCCGGCCGGCGAATCCTGGTGGTTGGTGCGGGCCAGCGCCAGACTGTAGATCAGGTCCCTTCCGTCGGAAACGGCCGCG
CCATGTCGGTGCTGTTTGCGCGCGAGGGCGCGGCAGTGACTTGCGCCGACATCGACCCCGGTGCCGCCCAAGGGACGGTT
GACTGGATCGCTCGCGAAGGGGGACGCGGCTTCGTCGTGCAAGCTGACGTTTCCGATCCTGCCCAGATTGTCCGGATGGT
GCGCGAAGCCGCATCGGCCATGGATGGCCTGGACGGGCTGGTCGTCAATGTCGGTATCGGAAACCAGAACCGGTTCGGCA
GCGAAAACCCTGCCGACTGGGATCGTGTCCAAGATCTGAACCTGCGGGCGCCAATGTTCTGCGCGCAGGAGGCGGCGGCG
GTCATGCCGCCGGGCAGCGCAGTCGTCTTCGTCGCCTCGACTGCTGCCATTTCACCGCTGAGCGGCCTGCCGGCCTATGA
ATCGTCCAAGGCCGGGCTGATGGCGCTCGGTCGCGCCGTCGCCTTTGCCGGGCAAGGCACCGGACTGCGCGCCAACGTGC
TCGCGCCAGGCCTGATCGACACGCCAATGGGACGCGACGCCTCACGTGCCAGGCCGTCGCGCGCGGCGCGCCCCCTGCCC
TTTGGCCGGCAGGGAACGGGCTGGGAAGTCGCCAACGCCGCGCTCTTCCTGATCAGTGCCGAATCCTCCTATGTCAACGG
GCAGATGCTGGTCGTGGACGGCGGATTGTCCATTGGCGCCGTGCGCGCCACCGCCTGA

Upstream 100 bases:

>100_bases
CTGCTGGTGACCATCGGCTACTACATGCTGGTGTCGCGCCTGTTGGAAAACCTGGAAGTCGATATTGAGAACCCGCCGAT
TGAACATCTGGAGATGCACC

Downstream 100 bases:

>100_bases
GTTACCCGGCGACGATCGGGCATACCAAGGAGGAGACATCAATGAAAATCTTGACCTTATGTGCTGACCGCGCTGCCGTG
GCCGCACAGTACCTGATGCG

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTDSLQLRPDQQLFAPALGTVRREGRLAGRRILVVGAGQRQTVDQVPSVGNGRAMSVLFAREGAAVTCADIDPGAAQGTV
DWIAREGGRGFVVQADVSDPAQIVRMVREAASAMDGLDGLVVNVGIGNQNRFGSENPADWDRVQDLNLRAPMFCAQEAAA
VMPPGSAVVFVASTAAISPLSGLPAYESSKAGLMALGRAVAFAGQGTGLRANVLAPGLIDTPMGRDASRARPSRAARPLP
FGRQGTGWEVANAALFLISAESSYVNGQMLVVDGGLSIGAVRATA

Sequences:

>Translated_285_residues
MTDSLQLRPDQQLFAPALGTVRREGRLAGRRILVVGAGQRQTVDQVPSVGNGRAMSVLFAREGAAVTCADIDPGAAQGTV
DWIAREGGRGFVVQADVSDPAQIVRMVREAASAMDGLDGLVVNVGIGNQNRFGSENPADWDRVQDLNLRAPMFCAQEAAA
VMPPGSAVVFVASTAAISPLSGLPAYESSKAGLMALGRAVAFAGQGTGLRANVLAPGLIDTPMGRDASRARPSRAARPLP
FGRQGTGWEVANAALFLISAESSYVNGQMLVVDGGLSIGAVRATA
>Mature_284_residues
TDSLQLRPDQQLFAPALGTVRREGRLAGRRILVVGAGQRQTVDQVPSVGNGRAMSVLFAREGAAVTCADIDPGAAQGTVD
WIAREGGRGFVVQADVSDPAQIVRMVREAASAMDGLDGLVVNVGIGNQNRFGSENPADWDRVQDLNLRAPMFCAQEAAAV
MPPGSAVVFVASTAAISPLSGLPAYESSKAGLMALGRAVAFAGQGTGLRANVLAPGLIDTPMGRDASRARPSRAARPLPF
GRQGTGWEVANAALFLISAESSYVNGQMLVVDGGLSIGAVRATA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=31.203007518797, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=30.6122448979592, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=31.25, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=235, Percent_Identity=28.0851063829787, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=264, Percent_Identity=26.8939393939394, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723750, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4504505, Length=272, Percent_Identity=26.1029411764706, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=29.4776119402985, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=28.7937743190661, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI2367175, Length=239, Percent_Identity=32.6359832635983, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=28.5171102661597, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=31.8897637795276, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=267, Percent_Identity=30.3370786516854, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082160, Length=234, Percent_Identity=29.0598290598291, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788459, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=30.46875, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789208, Length=233, Percent_Identity=28.3261802575107, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=25.78125, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787545, Length=264, Percent_Identity=27.6515151515151, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=235, Percent_Identity=31.063829787234, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=167, Percent_Identity=34.1317365269461, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=250, Percent_Identity=29.6, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=188, Percent_Identity=26.063829787234, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=149, Percent_Identity=30.8724832214765, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=143, Percent_Identity=31.4685314685315, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=26.1818181818182, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=251, Percent_Identity=29.8804780876494, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=26.8382352941176, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=24.4525547445255, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=26.7399267399267, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=32.1705426356589, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=27.6859504132231, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=29.9212598425197, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.1158301158301, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=29.5019157088123, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357041, Length=236, Percent_Identity=29.2372881355932, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18859837, Length=209, Percent_Identity=28.7081339712919, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29438; Mature: 29307

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSLQLRPDQQLFAPALGTVRREGRLAGRRILVVGAGQRQTVDQVPSVGNGRAMSVLFA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEEEE
REGAAVTCADIDPGAAQGTVDWIAREGGRGFVVQADVSDPAQIVRMVREAASAMDGLDGL
CCCCEEEEECCCCCCCCCHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCE
VVNVGIGNQNRFGSENPADWDRVQDLNLRAPMFCAQEAAAVMPPGSAVVFVASTAAISPL
EEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHCCEECCCCCEEEEEEECCCCCCC
SGLPAYESSKAGLMALGRAVAFAGQGTGLRANVLAPGLIDTPMGRDASRARPSRAARPLP
CCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCC
FGRQGTGWEVANAALFLISAESSYVNGQMLVVDGGLSIGAVRATA
CCCCCCCCEECCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECC
>Mature Secondary Structure 
TDSLQLRPDQQLFAPALGTVRREGRLAGRRILVVGAGQRQTVDQVPSVGNGRAMSVLFA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEEEE
REGAAVTCADIDPGAAQGTVDWIAREGGRGFVVQADVSDPAQIVRMVREAASAMDGLDGL
CCCCEEEEECCCCCCCCCHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCE
VVNVGIGNQNRFGSENPADWDRVQDLNLRAPMFCAQEAAAVMPPGSAVVFVASTAAISPL
EEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHCCEECCCCCEEEEEEECCCCCCC
SGLPAYESSKAGLMALGRAVAFAGQGTGLRANVLAPGLIDTPMGRDASRARPSRAARPLP
CCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCC
FGRQGTGWEVANAALFLISAESSYVNGQMLVVDGGLSIGAVRATA
CCCCCCCCEECCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]