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The map label for this gene is btr [H]

Identifier: 73540846

GI number: 73540846

Start: 1238565

End: 1239350

Strand: Reverse

Name: btr [H]

Synonym: Reut_A1147

Alternate gene names: 73540846

Gene position: 1239350-1238565 (Counterclockwise)

Preceding gene: 73540847

Following gene: 73540841

Centisome position: 32.56

GC content: 61.83

Gene sequence:

>786_bases
ATGTTCGGAACCAGTGACTCGCCGTCGGCCGACCTCGAGCAACACGCGATCAGCGCCCCCCTTGACCGCCATGCAAGGCT
GTCCACCGAAAACGCACCGAAGCCGGGTGCCCAGTGCTCCACCTGCATGCTCCGGCACATCTGCATGGCGTCCAACCTCG
ACGAGACGGACATAGTGCGCCTGAACAGCGTGGTGAAGAACTGGAAGATGGTCAGGCAAGGTCAAGCGCTCTACCGCGCC
GGAGATCCGTTCCAGAGTATCTACGCGCTGCGTTCGGGCTCGATCAAGACCGTGCTCTCTCACCCTAGCGGCAGGGAATG
CGTGTCCGGCTTTTTCCTTCCCGGCGAAACGCTCGGCCTCGACGGCATTTCGACAGAGGTCCACACCTGCGACGCCATTG
CCCTGGAAGACAGCGCCGTCTGCGTGATCCCGTTCCACCTGCTGGAAGCCCTTTGCCGCGAAGTCAAATCGCTGCAGCAA
CAGGTGCACAAGATGATGAGCGCGGAAATCGTGCGCGAGACCGGCCAGATGATGCTGCTCGGCAACCTCACGGCGGAGCA
GCGCGTGGCGGCCTTCCTGCTCAACATCTCGCGTCGCCTGCAGCGCAGGGGCTATTCGCCGACATGCTTTACGTTGCGCA
TGACGCGCGAGGACATCGGCAGTTATCTGGGCATGACCCTGGAGACCGCGAGCCGCACGCTGTCGCGCTTCCAGCAGGAA
GGACTGATTCGGGTACAGGGCAAGCAGATCGAACTGCTGGATCTTGAAGCACTCGATCTGCGATAA

Upstream 100 bases:

>100_bases
AGATCTCCGGCACAGCACCAAGAAGCAGCGAACCATAGGAGTACCGGGCTCTCGGGGCCAGCAGACGCGCCCCTGATAGC
ACCGCCATCTGGAGACAACG

Downstream 100 bases:

>100_bases
ACCTATGACGTTGCTCATGCCGGTCGGACAGGCGCAAGTGCGGTGCTTCGTCCTGATGTTCCAGGCTGGTCGCCAGCTTG
CCGGCAATTGCCTGGCTGAC

Product: cyclic nucleotide-binding: regulatory protein, Crp

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFGTSDSPSADLEQHAISAPLDRHARLSTENAPKPGAQCSTCMLRHICMASNLDETDIVRLNSVVKNWKMVRQGQALYRA
GDPFQSIYALRSGSIKTVLSHPSGRECVSGFFLPGETLGLDGISTEVHTCDAIALEDSAVCVIPFHLLEALCREVKSLQQ
QVHKMMSAEIVRETGQMMLLGNLTAEQRVAAFLLNISRRLQRRGYSPTCFTLRMTREDIGSYLGMTLETASRTLSRFQQE
GLIRVQGKQIELLDLEALDLR

Sequences:

>Translated_261_residues
MFGTSDSPSADLEQHAISAPLDRHARLSTENAPKPGAQCSTCMLRHICMASNLDETDIVRLNSVVKNWKMVRQGQALYRA
GDPFQSIYALRSGSIKTVLSHPSGRECVSGFFLPGETLGLDGISTEVHTCDAIALEDSAVCVIPFHLLEALCREVKSLQQ
QVHKMMSAEIVRETGQMMLLGNLTAEQRVAAFLLNISRRLQRRGYSPTCFTLRMTREDIGSYLGMTLETASRTLSRFQQE
GLIRVQGKQIELLDLEALDLR
>Mature_261_residues
MFGTSDSPSADLEQHAISAPLDRHARLSTENAPKPGAQCSTCMLRHICMASNLDETDIVRLNSVVKNWKMVRQGQALYRA
GDPFQSIYALRSGSIKTVLSHPSGRECVSGFFLPGETLGLDGISTEVHTCDAIALEDSAVCVIPFHLLEALCREVKSLQQ
QVHKMMSAEIVRETGQMMLLGNLTAEQRVAAFLLNISRRLQRRGYSPTCFTLRMTREDIGSYLGMTLETASRTLSRFQQE
GLIRVQGKQIELLDLEALDLR

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=221, Percent_Identity=42.0814479638009, Blast_Score=191, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28971; Mature: 28971

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGTSDSPSADLEQHAISAPLDRHARLSTENAPKPGAQCSTCMLRHICMASNLDETDIVR
CCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LNSVVKNWKMVRQGQALYRAGDPFQSIYALRSGSIKTVLSHPSGRECVSGFFLPGETLGL
HHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCC
DGISTEVHTCDAIALEDSAVCVIPFHLLEALCREVKSLQQQVHKMMSAEIVRETGQMMLL
CCCCCCHHHCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
GNLTAEQRVAAFLLNISRRLQRRGYSPTCFTLRMTREDIGSYLGMTLETASRTLSRFQQE
ECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GLIRVQGKQIELLDLEALDLR
CCEEECCCEEEEEECEECCCC
>Mature Secondary Structure
MFGTSDSPSADLEQHAISAPLDRHARLSTENAPKPGAQCSTCMLRHICMASNLDETDIVR
CCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LNSVVKNWKMVRQGQALYRAGDPFQSIYALRSGSIKTVLSHPSGRECVSGFFLPGETLGL
HHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCCCCC
DGISTEVHTCDAIALEDSAVCVIPFHLLEALCREVKSLQQQVHKMMSAEIVRETGQMMLL
CCCCCCHHHCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
GNLTAEQRVAAFLLNISRRLQRRGYSPTCFTLRMTREDIGSYLGMTLETASRTLSRFQQE
ECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GLIRVQGKQIELLDLEALDLR
CCEEECCCEEEEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]