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The map label for this gene is lpxH [H]

Identifier: 73540820

GI number: 73540820

Start: 1211025

End: 1211876

Strand: Reverse

Name: lpxH [H]

Synonym: Reut_A1118

Alternate gene names: 73540820

Gene position: 1211876-1211025 (Counterclockwise)

Preceding gene: 73540821

Following gene: 73540817

Centisome position: 31.84

GC content: 67.72

Gene sequence:

>852_bases
TTGCGGCTTCATGCACGCTTCCCTGCCGACAACTACATCGACCTGGCCGCGCGCATGACCGCAATCCCCACCACGCCGGT
GGCCGGTCCCCTCGAGGTACAGGCGCCGGCGTGGTTCATTTCCGATCTGCACCTGACGCCAGGCATGCCGCGCACGCTGG
CCGCGTTCGAGCGCGTGCTCGAACGTGCCGCCATGGAAGCGCGCACGCTGTTCATCCTTGGCGATTTCTTCGAGTTCTGG
GTCGGTGACGAAGAGACCAGTTCGCCGTTCGCCGCACGGGTGGCCACGGCGCTGCGCACGCTGGCAGGACGTGGCGTGCC
GGTCTACCTGATGCACGGAAATCGCGATTTCCTGCTCGGCAAGCGCTTCGCCAAAGCGGCGGGAGCCACCTTGCTTCCGG
ATCCCACCGTCATTCTGTGCGCCGGCCAGCGCGTGGTGCTCAGCCATGGCGACATGCTGTGCACCGACGACGAGCGCTAC
AACCGTTTCCGACGATGGACCCGCAAGCGCTGGGTGCAACGGGTATTCCTCGCCCTGCCGCTGTCCGCACGTCTCGGCGT
GGCCCGTCGGCTGCGTGCCGACAGCGAAGCCGGCCGCCAGCGCCAGGTTGACCAGGGACAGCCGACCCACGTCGTGTACG
GAGATACCTCGCCGGCCGCGGTGACCGCCCTTCTCGAGGCCAGCGATGCCAGGCTGCTCGTCCATGGCCACACTCACCGG
CCCGCACGGCATCAGGATGCCGCCGGCGTGCGATGGGTGCTGACCGATTGGGATCTCGATGGCAGCCAGCCGCGCGCCGC
GGTGCTGCAGCTCGACGAAGGCGGCTTTCACGTGCTGCCGCAGACGACATAA

Upstream 100 bases:

>100_bases
CGCACCGGCAGCTCGGGCTTCCATCAGGACGTGCCGCTGGAAGACGTCGTGATCGAAAAGGCTGTGGTCGTCGAGTAAGA
ACGCGATCCATGCTTCACGA

Downstream 100 bases:

>100_bases
GGGGCAGCCGCGGCTGCCCCTAATTTTTTGCTTCGCCGTCGCCTGTCGCCTACTTCATCAGCCTGCGCAGTTCGCTGGCA
TCGAAGCGGTCGTTCGGCGT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRLHARFPADNYIDLAARMTAIPTTPVAGPLEVQAPAWFISDLHLTPGMPRTLAAFERVLERAAMEARTLFILGDFFEFW
VGDEETSSPFAARVATALRTLAGRGVPVYLMHGNRDFLLGKRFAKAAGATLLPDPTVILCAGQRVVLSHGDMLCTDDERY
NRFRRWTRKRWVQRVFLALPLSARLGVARRLRADSEAGRQRQVDQGQPTHVVYGDTSPAAVTALLEASDARLLVHGHTHR
PARHQDAAGVRWVLTDWDLDGSQPRAAVLQLDEGGFHVLPQTT

Sequences:

>Translated_283_residues
MRLHARFPADNYIDLAARMTAIPTTPVAGPLEVQAPAWFISDLHLTPGMPRTLAAFERVLERAAMEARTLFILGDFFEFW
VGDEETSSPFAARVATALRTLAGRGVPVYLMHGNRDFLLGKRFAKAAGATLLPDPTVILCAGQRVVLSHGDMLCTDDERY
NRFRRWTRKRWVQRVFLALPLSARLGVARRLRADSEAGRQRQVDQGQPTHVVYGDTSPAAVTALLEASDARLLVHGHTHR
PARHQDAAGVRWVLTDWDLDGSQPRAAVLQLDEGGFHVLPQTT
>Mature_283_residues
MRLHARFPADNYIDLAARMTAIPTTPVAGPLEVQAPAWFISDLHLTPGMPRTLAAFERVLERAAMEARTLFILGDFFEFW
VGDEETSSPFAARVATALRTLAGRGVPVYLMHGNRDFLLGKRFAKAAGATLLPDPTVILCAGQRVVLSHGDMLCTDDERY
NRFRRWTRKRWVQRVFLALPLSARLGVARRLRADSEAGRQRQVDQGQPTHVVYGDTSPAAVTALLEASDARLLVHGHTHR
PARHQDAAGVRWVLTDWDLDGSQPRAAVLQLDEGGFHVLPQTT

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=231, Percent_Identity=42.8571428571429, Blast_Score=184, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 31431; Mature: 31431

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHARFPADNYIDLAARMTAIPTTPVAGPLEVQAPAWFISDLHLTPGMPRTLAAFERVL
CEEECCCCCCCHHHHHHHHEECCCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHH
ERAAMEARTLFILGDFFEFWVGDEETSSPFAARVATALRTLAGRGVPVYLMHGNRDFLLG
HHHHHHHHEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHH
KRFAKAAGATLLPDPTVILCAGQRVVLSHGDMLCTDDERYNRFRRWTRKRWVQRVFLALP
HHHHHHCCCEECCCCCEEEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
LSARLGVARRLRADSEAGRQRQVDQGQPTHVVYGDTSPAAVTALLEASDARLLVHGHTHR
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCC
PARHQDAAGVRWVLTDWDLDGSQPRAAVLQLDEGGFHVLPQTT
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEECCCCC
>Mature Secondary Structure
MRLHARFPADNYIDLAARMTAIPTTPVAGPLEVQAPAWFISDLHLTPGMPRTLAAFERVL
CEEECCCCCCCHHHHHHHHEECCCCCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHH
ERAAMEARTLFILGDFFEFWVGDEETSSPFAARVATALRTLAGRGVPVYLMHGNRDFLLG
HHHHHHHHEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHH
KRFAKAAGATLLPDPTVILCAGQRVVLSHGDMLCTDDERYNRFRRWTRKRWVQRVFLALP
HHHHHHCCCEECCCCCEEEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
LSARLGVARRLRADSEAGRQRQVDQGQPTHVVYGDTSPAAVTALLEASDARLLVHGHTHR
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCC
PARHQDAAGVRWVLTDWDLDGSQPRAAVLQLDEGGFHVLPQTT
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]