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The map label for this gene is hscB [H]

Identifier: 73540764

GI number: 73540764

Start: 1152815

End: 1153333

Strand: Direct

Name: hscB [H]

Synonym: Reut_A1062

Alternate gene names: 73540764

Gene position: 1152815-1153333 (Clockwise)

Preceding gene: 73540763

Following gene: 73540765

Centisome position: 30.29

GC content: 65.51

Gene sequence:

>519_bases
TTGAAAGACGATTTTTTTGCGCTGTTCGGCCTGCCGGTGCAGTTCGGCGTCGATGAAGCGGCGTTGGACGCCGCGTATCG
CACCGTGCAGTCGCAGGCACACCCGGACCGCTTTGCCAAGGCGGGCGAGGCTGAGCGGCGCGTGGCCATGCAGTGGGCCG
CGCATGCCAACGAGGCTTACCGTACGCTGCGCCAGCCGCTCAAACGCGCGATCTACCTGCTGGGACTGCGCGGCGTGGAC
GTGCAGGCGGAGAACAACACCGCCATGTCACCCGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGGATCTGCAGGACGC
CGTCGAGTCCCGTGATGTCGATCGCCTTGATGGCTTGCTGCGCGGCCTGCGCCAGGAAAAGCGCGAGCGGCACACCGCGC
TTGGCAAGCTGCTCGATGCCGGAGACAACGAAGCCGCAGGCGCGGCGGTGCGGCAGCTGATGTTCATCGAGAAGATCGAA
CACGATACCAGCGAGGCGATCGACCGGCTGGAAGGGTAG

Upstream 100 bases:

>100_bases
AACCGCCGGCCGAATGGGCGCAGTTCACTCAAGGCGCCGGACGCGGTTGACGTGAATGCACAAGGGGGCGGCGCGGCCGC
TCCTTTTTGTTGGGGAAGCT

Downstream 100 bases:

>100_bases
TCCCGGCACGTTTGGCGGGGCCATGTGACAATGGCGCCCGTCGCGAAAGCCGCCTGTGCGGCGGACATCATCGCGCACGA
GAAAGCGAAGAATCATCATG

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKDDFFALFGLPVQFGVDEAALDAAYRTVQSQAHPDRFAKAGEAERRVAMQWAAHANEAYRTLRQPLKRAIYLLGLRGVD
VQAENNTAMSPAFLMQQMEWREDLQDAVESRDVDRLDGLLRGLRQEKRERHTALGKLLDAGDNEAAGAAVRQLMFIEKIE
HDTSEAIDRLEG

Sequences:

>Translated_172_residues
MKDDFFALFGLPVQFGVDEAALDAAYRTVQSQAHPDRFAKAGEAERRVAMQWAAHANEAYRTLRQPLKRAIYLLGLRGVD
VQAENNTAMSPAFLMQQMEWREDLQDAVESRDVDRLDGLLRGLRQEKRERHTALGKLLDAGDNEAAGAAVRQLMFIEKIE
HDTSEAIDRLEG
>Mature_172_residues
MKDDFFALFGLPVQFGVDEAALDAAYRTVQSQAHPDRFAKAGEAERRVAMQWAAHANEAYRTLRQPLKRAIYLLGLRGVD
VQAENNTAMSPAFLMQQMEWREDLQDAVESRDVDRLDGLLRGLRQEKRERHTALGKLLDAGDNEAAGAAVRQLMFIEKIE
HDTSEAIDRLEG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=157, Percent_Identity=26.7515923566879, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1788876, Length=156, Percent_Identity=39.7435897435897, Blast_Score=123, Evalue=6e-30,
Organism=Drosophila melanogaster, GI161084223, Length=169, Percent_Identity=28.4023668639053, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19412; Mature: 19412

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDFFALFGLPVQFGVDEAALDAAYRTVQSQAHPDRFAKAGEAERRVAMQWAAHANEAY
CCCCHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
RTLRQPLKRAIYLLGLRGVDVQAENNTAMSPAFLMQQMEWREDLQDAVESRDVDRLDGLL
HHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RGLRQEKRERHTALGKLLDAGDNEAAGAAVRQLMFIEKIEHDTSEAIDRLEG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MKDDFFALFGLPVQFGVDEAALDAAYRTVQSQAHPDRFAKAGEAERRVAMQWAAHANEAY
CCCCHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
RTLRQPLKRAIYLLGLRGVDVQAENNTAMSPAFLMQQMEWREDLQDAVESRDVDRLDGLL
HHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RGLRQEKRERHTALGKLLDAGDNEAAGAAVRQLMFIEKIEHDTSEAIDRLEG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA