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The map label for this gene is ppnK [H]

Identifier: 73540738

GI number: 73540738

Start: 1129932

End: 1130888

Strand: Reverse

Name: ppnK [H]

Synonym: Reut_A1035

Alternate gene names: 73540738

Gene position: 1130888-1129932 (Counterclockwise)

Preceding gene: 73540742

Following gene: 73540737

Centisome position: 29.71

GC content: 65.52

Gene sequence:

>957_bases
ATGCTGACAACGGTCACAGCGGTATGGTCTAATCCCGGCATGTCTGCCCCCCAGAAAACCAGCGCCTTGCGCACCCCATT
CAAGACCGTGGCCCTCGTGGGCCGGTACTCGACTGCCGGCATCGAAGGCCCGCTGGAGGAGCTTGCGTCCTACATCCTCC
GGAATGGCCAGGATGTTGTCTTCGAGCGCGAGACCTCACTGGCCACCGGCCTGACGGGCTACCCGGCCCTGACCGCCGAG
GAGATCGGCCGGGAAGCGGACGTGGCCGTGGTGCTCGGTGGCGACGGCACACTGCTCGGCATCGCCCGACAGCTTGCCGG
CCACAATGTGCCGCTGATCGGCGTCAACCACGGCCGGCTCGGTTTCATGACCGACATCCCGCTCGAAGACGTGCAATCGG
TGCTGCCTGACATGCTGGGGGGGCGCTACGAGGCCGAGACCCGGCTGCTGCTGGAATCGAGCGTGGTGCGCGACGACAGC
CCGATTTTCTCGGCGCTGGCGCTCAACGACGTGGTCGTCAACCGCTCGGGCATTTCCGGCATGGTCGAACTGGCGGTGTC
GGTCGATGGCTATTTCATGTACAACCAGCGTTCGGACGGCTTGATCGTGTCCACCGCGACCGGCTCGACGGCGTATGCGC
TGTCGGCCGGCGGCCCGATCCTGCATCCGACGCTGTCTGGCCTGGTGCTCGTGCCGATCGCCCCGCATTCGCTGTCCAAC
CGGCCGATCGTGCTGCCGCAGGAGGCGGAGGTTACGATCGAGGTTGCGACCGCGCGCGATGCCAGCGTCAACTTCGACAT
GCAGTCGCTGACCTCGCTCTTGCCGGGCGACCGCATCGTCGTGCGCCGTTCGAAGAAGACCATCCAGCTGCTGCACCCGG
TGGGCTACAACTACTACGCTACGCTGCGCAAGAAGCTGCACTGGCACGAATATCCGACCGAGGACAACCGGCTCTGA

Upstream 100 bases:

>100_bases
GAGCAGCGTTTTGGAACGTTCATCCATGATGCCCCGATTTTACGCAAGTTTTACAGCTTCGGGCGCCCGCGCGGCCGGTG
CCCGGTGGCGCGCCCGGCCC

Downstream 100 bases:

>100_bases
GCCTGAGGCCCGGCGCCTTCCGTCCGCACTGACCGAAACCCTTCACCGCCACGATGCTGCGCAGCCTGTCCATCCGTGAT
TTCGTCATCGTCGATACGCT

Product: NAD(+)/NADH kinase family protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MLTTVTAVWSNPGMSAPQKTSALRTPFKTVALVGRYSTAGIEGPLEELASYILRNGQDVVFERETSLATGLTGYPALTAE
EIGREADVAVVLGGDGTLLGIARQLAGHNVPLIGVNHGRLGFMTDIPLEDVQSVLPDMLGGRYEAETRLLLESSVVRDDS
PIFSALALNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTATGSTAYALSAGGPILHPTLSGLVLVPIAPHSLSN
RPIVLPQEAEVTIEVATARDASVNFDMQSLTSLLPGDRIVVRRSKKTIQLLHPVGYNYYATLRKKLHWHEYPTEDNRL

Sequences:

>Translated_318_residues
MLTTVTAVWSNPGMSAPQKTSALRTPFKTVALVGRYSTAGIEGPLEELASYILRNGQDVVFERETSLATGLTGYPALTAE
EIGREADVAVVLGGDGTLLGIARQLAGHNVPLIGVNHGRLGFMTDIPLEDVQSVLPDMLGGRYEAETRLLLESSVVRDDS
PIFSALALNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTATGSTAYALSAGGPILHPTLSGLVLVPIAPHSLSN
RPIVLPQEAEVTIEVATARDASVNFDMQSLTSLLPGDRIVVRRSKKTIQLLHPVGYNYYATLRKKLHWHEYPTEDNRL
>Mature_318_residues
MLTTVTAVWSNPGMSAPQKTSALRTPFKTVALVGRYSTAGIEGPLEELASYILRNGQDVVFERETSLATGLTGYPALTAE
EIGREADVAVVLGGDGTLLGIARQLAGHNVPLIGVNHGRLGFMTDIPLEDVQSVLPDMLGGRYEAETRLLLESSVVRDDS
PIFSALALNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTATGSTAYALSAGGPILHPTLSGLVLVPIAPHSLSN
RPIVLPQEAEVTIEVATARDASVNFDMQSLTSLLPGDRIVVRRSKKTIQLLHPVGYNYYATLRKKLHWHEYPTEDNRL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=337, Percent_Identity=28.1899109792285, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=39.7923875432526, Blast_Score=218, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6320794, Length=301, Percent_Identity=27.2425249169435, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=31.25, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325068, Length=181, Percent_Identity=32.0441988950276, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573826, Length=333, Percent_Identity=28.8288288288288, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573828, Length=333, Percent_Identity=30.6306306306306, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573832, Length=333, Percent_Identity=28.8288288288288, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI161077047, Length=334, Percent_Identity=29.940119760479, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28573830, Length=333, Percent_Identity=28.8288288288288, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI20129957, Length=284, Percent_Identity=29.9295774647887, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363321, Length=284, Percent_Identity=29.9295774647887, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653422, Length=284, Percent_Identity=29.9295774647887, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363323, Length=284, Percent_Identity=29.9295774647887, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653424, Length=284, Percent_Identity=29.9295774647887, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34179; Mature: 34179

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTVTAVWSNPGMSAPQKTSALRTPFKTVALVGRYSTAGIEGPLEELASYILRNGQDVV
CCEEEEEEECCCCCCCCCHHHHHHCCHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCEEE
FERETSLATGLTGYPALTAEEIGREADVAVVLGGDGTLLGIARQLAGHNVPLIGVNHGRL
EECCCHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCE
GFMTDIPLEDVQSVLPDMLGGRYEAETRLLLESSVVRDDSPIFSALALNDVVVNRSGISG
EEEECCCHHHHHHHHHHHHCCCCCHHHEEEEHHHHCCCCCCHHHHHHHHHEEEECCCCCC
MVELAVSVDGYFMYNQRSDGLIVSTATGSTAYALSAGGPILHPTLSGLVLVPIAPHSLSN
EEEEEEEECEEEEEECCCCCEEEEECCCCEEEEEECCCCEECCCCCCEEEEEECCCCCCC
RPIVLPQEAEVTIEVATARDASVNFDMQSLTSLLPGDRIVVRRSKKTIQLLHPVGYNYYA
CCEEECCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHH
TLRKKLHWHEYPTEDNRL
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLTTVTAVWSNPGMSAPQKTSALRTPFKTVALVGRYSTAGIEGPLEELASYILRNGQDVV
CCEEEEEEECCCCCCCCCHHHHHHCCHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCEEE
FERETSLATGLTGYPALTAEEIGREADVAVVLGGDGTLLGIARQLAGHNVPLIGVNHGRL
EECCCHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCE
GFMTDIPLEDVQSVLPDMLGGRYEAETRLLLESSVVRDDSPIFSALALNDVVVNRSGISG
EEEECCCHHHHHHHHHHHHCCCCCHHHEEEEHHHHCCCCCCHHHHHHHHHEEEECCCCCC
MVELAVSVDGYFMYNQRSDGLIVSTATGSTAYALSAGGPILHPTLSGLVLVPIAPHSLSN
EEEEEEEECEEEEEECCCCCEEEEECCCCEEEEEECCCCEECCCCCCEEEEEECCCCCCC
RPIVLPQEAEVTIEVATARDASVNFDMQSLTSLLPGDRIVVRRSKKTIQLLHPVGYNYYA
CCEEECCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHH
TLRKKLHWHEYPTEDNRL
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA