Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 73540730

GI number: 73540730

Start: 1115481

End: 1116977

Strand: Reverse

Name: tldD [H]

Synonym: Reut_A1027

Alternate gene names: 73540730

Gene position: 1116977-1115481 (Counterclockwise)

Preceding gene: 73540731

Following gene: 73540729

Centisome position: 29.34

GC content: 66.8

Gene sequence:

>1497_bases
ATGTCGGCGCATCTGCAAGAAAGAAAAGGACTGTTCATGAACGCCGGCGATCTCGGAATCCGCAACCTTGCCACCGCGCA
GCAACTGCTGCTGGCGCCGTACGGCCTGGACGAAGCCAAGCTGCAGCGCGTACTGGCCGACATCTTCACGCACAAGGTCG
ACTATGCCGACCTGTATTTCCAGTACACGCGCAACGAGGCGTGGAGCCTGGAAGAAGGCATCGTCAAATCGGGCAGCTTC
AGCATCGACCAGGGCGTCGGTGTACGCGCGGTCTCGGGCGACAAGACGGCCTTTGCCTATTCGGATGACATCAGCCTGCC
CGCGCTGTCGCAGGCCGCCGCGGCCACGCGCACCATCGGCCGCGCCGGCAGCGGCCGCGTCAAGGTGGCTGGCGAACTGG
CCTCGCAAACCGGCCGCAACCTGTACACGCCGAACGACCCGCTCGATTCGATGGCCGCTGCCGAGAAAGTGGCCCTGCTC
GAGCGCGTCGAGCGCATGGCGCGCGCGAAGGATCCGCGCGTCGTGCAGGTCATGGCTGGCCTGGCTGGCGAATATGACGT
GGTGCTGGTGGCGCGCAGCGACGGCGTGCTCGCCGCGGACGTGCGCCCGCTCGTGCGCGTGTCGGTCACCGTCATCGCCG
AACACAACGGGCGACGCGAGATGGGTTCGTCCGGCGGCGGCGGCCGATATGCCTACGGCTACTTCACGGATGAACTGCTG
CAGAAGTATGTCGATGAGGCCGTGTCGTCGGCGCTGGTCAACCTCGACGCACGTCCCGCACCGGCCGGCGCGATGACCGT
GGTGCTCGGTCCGGGCTGGCCCGGCGTGCTGCTGCACGAAGCCGTCGGCCACGGCCTGGAGGGCGACTTCAACCGCAAGG
GCTCGTCGGCCTTCGCGGGCCGCATGGGCGAACGCGTGGCCGCCAAGGGCGTGACCGTGGTCGACGACGGCACGCTGGCC
AACCGCCGCGGCTCGCTCAACCTGGACGACGAAGGCAACGCGACCCAGTGCACCACGCTGATCGAGGACGGCATCTTGCG
TGGCTATATCCAGGACACGCTCAACGCGCGCCTGATGAAGATGCCCGTGACCGGCAACGCGCGCCGCGAAAGCTACGCCG
CGCTGCCGATGCCGCGCATGACCAACACCTACATGCTCAACGGCGACCGCGATCCGCAGGAGATCATCGCCAGCGTGAAG
AAGGGTCTGTATGCCGTGAATTTCGGCGGCGGCCAGGTCGATATCACCAACGGCAAGTTCGTGTTCTCGGCGAGCGAGGC
GTACATGATCGAGGACGGGAAGATCACCTACCCCGTCAAGGGCGCCACGCTGGTCGGCAACGGCCCGGAATCGCTCAAGG
ACGTGACCATGATCGGCAACGACATGCGGCTGGACTCGGGCGTGGGCGTGTGTGGCAAGGAAGGCCAGAGCGTGCCGGTG
GGCGTCGGCCAGCCGACGCTGCGCATCGAGAACATGACGGTGGGCGGCACGGCGTAA

Upstream 100 bases:

>100_bases
GCTAGCCGAAGTCCGACAGAACCTGCCCGCGCTGCGACACCGGGTGCTGTAGCATTGGCGGTAACTCCGCCTTCCAACCT
GATTCACGACGCCGGCGACC

Downstream 100 bases:

>100_bases
TTGTTGACGGTCGCGTCCACGCCGCCGCTGGCCGGGCGCGGCACTTGCCAACTTTTGCAAAACGCGCTATAAAGATGCTT
CGTACTTTGGCAGTCAATCG

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSAHLQERKGLFMNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQYTRNEAWSLEEGIVKSGSF
SIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIGRAGSGRVKVAGELASQTGRNLYTPNDPLDSMAAAEKVALL
ERVERMARAKDPRVVQVMAGLAGEYDVVLVARSDGVLAADVRPLVRVSVTVIAEHNGRREMGSSGGGGRYAYGYFTDELL
QKYVDEAVSSALVNLDARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTLA
NRRGSLNLDDEGNATQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEIIASVK
KGLYAVNFGGGQVDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPV
GVGQPTLRIENMTVGGTA

Sequences:

>Translated_498_residues
MSAHLQERKGLFMNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQYTRNEAWSLEEGIVKSGSF
SIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIGRAGSGRVKVAGELASQTGRNLYTPNDPLDSMAAAEKVALL
ERVERMARAKDPRVVQVMAGLAGEYDVVLVARSDGVLAADVRPLVRVSVTVIAEHNGRREMGSSGGGGRYAYGYFTDELL
QKYVDEAVSSALVNLDARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTLA
NRRGSLNLDDEGNATQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEIIASVK
KGLYAVNFGGGQVDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPV
GVGQPTLRIENMTVGGTA
>Mature_497_residues
SAHLQERKGLFMNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQYTRNEAWSLEEGIVKSGSFS
IDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIGRAGSGRVKVAGELASQTGRNLYTPNDPLDSMAAAEKVALLE
RVERMARAKDPRVVQVMAGLAGEYDVVLVARSDGVLAADVRPLVRVSVTVIAEHNGRREMGSSGGGGRYAYGYFTDELLQ
KYVDEAVSSALVNLDARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTLAN
RRGSLNLDDEGNATQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEIIASVKK
GLYAVNFGGGQVDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVG
VGQPTLRIENMTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=60.6625258799172, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1790682, Length=428, Percent_Identity=23.5981308411215, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52863; Mature: 52731

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHLQERKGLFMNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYF
CCCCCCHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
QYTRNEAWSLEEGIVKSGSFSIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIG
EEECCCCCCHHHHHHCCCCCEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHC
RAGSGRVKVAGELASQTGRNLYTPNDPLDSMAAAEKVALLERVERMARAKDPRVVQVMAG
CCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHC
LAGEYDVVLVARSDGVLAADVRPLVRVSVTVIAEHNGRREMGSSGGGGRYAYGYFTDELL
CCCCCEEEEEECCCCEEEECCCCEEEEEEEEEEECCCCHHCCCCCCCCCEEECHHHHHHH
QKYVDEAVSSALVNLDARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAG
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
RMGERVAAKGVTVVDDGTLANRRGSLNLDDEGNATQCTTLIEDGILRGYIQDTLNARLMK
HHCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
MPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEIIASVKKGLYAVNFGGGQVDITNGKF
ECCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEE
VFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPV
EEECCCEEEEECCEEEEEECCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCC
GVGQPTLRIENMTVGGTA
CCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
SAHLQERKGLFMNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYF
CCCCCHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
QYTRNEAWSLEEGIVKSGSFSIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIG
EEECCCCCCHHHHHHCCCCCEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHC
RAGSGRVKVAGELASQTGRNLYTPNDPLDSMAAAEKVALLERVERMARAKDPRVVQVMAG
CCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHC
LAGEYDVVLVARSDGVLAADVRPLVRVSVTVIAEHNGRREMGSSGGGGRYAYGYFTDELL
CCCCCEEEEEECCCCEEEECCCCEEEEEEEEEEECCCCHHCCCCCCCCCEEECHHHHHHH
QKYVDEAVSSALVNLDARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAG
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
RMGERVAAKGVTVVDDGTLANRRGSLNLDDEGNATQCTTLIEDGILRGYIQDTLNARLMK
HHCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
MPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEIIASVKKGLYAVNFGGGQVDITNGKF
ECCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEE
VFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPV
EEECCCEEEEECCEEEEEECCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCC
GVGQPTLRIENMTVGGTA
CCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]