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The map label for this gene is ureD

Identifier: 73540694

GI number: 73540694

Start: 1080297

End: 1081166

Strand: Direct

Name: ureD

Synonym: Reut_A0991

Alternate gene names: 73540694

Gene position: 1080297-1081166 (Clockwise)

Preceding gene: 73540693

Following gene: 73540695

Centisome position: 28.38

GC content: 68.39

Gene sequence:

>870_bases
ATGCGTCATCCCGATTTTCCTTCCGCCGTTGCCGTGCCGCCTGCATGGCAGGCCAGCCTGCGCCTGCGTTTTGCCGCGCG
CGGCGAACGTACCGTACTGGCCGCGCGGCAGCACCGTGGCCCGTTGATGGTGCAGAAGCCCCTCTATCCGGAGGGTGACA
TCTGCCATGCCGTCATCCTGCATCCACCGGCTGGCGTGGCCGGGGGCGACACGCTCGATATTGCCCTGCATGCGGAAGCG
GGTACTCATGCTGTCATCGCCACGCCGGGCGCCACGAAGTGGTACAAGTCGCTAGGCCGTGACGCGTCGCAGCATGTGCG
ACTTACCGTCGAGGAAGGCGCGCGGCTTGACTGGCTGCCGCAGGAGAACATCGTGTTCGACGATGCGCGTGCGCGCATTG
CGACCGAACTTTCAATTGCGCCTGGCGGCAGCGCGATCGGCTGGGATGCCGTCGTGCTGGGCCGGCAAGCATCGGGCGAG
CAGTGGAACCGGGGCGTGCTGTGGCTAGACACGCAGGTGCGCTGCAATGGCCATGCGCTGTGGATCGAGCAATCGCAGCT
CGATGCCGGGTCGCCACTGCGCGGTGCGGTGGCTGGGCTCGACGGCATGTCGGTGCTCGGCACGCTGTGGGCGGTCGGAC
ATGGCGCGACGCAAGAACTGGCCGAGTCGCTCGCGGAACGCCTGCCTTACGCGGCTGGTCTGCGCGCCGGGGTGACATGC
CTGTCGTCACCGGCGCAGTCGATGCTGCTGGTGCGCGTGCTGGGCCGGCAGATGGAAGCGGTCAGGCATGTCATGGTCGA
CGCATGGAGCGCGCTGCGCGAGCCGATCCACGGCGTGCCGGCGCGGCCGCTGCGGCTGTGGGCCACCTGA

Upstream 100 bases:

>100_bases
CTTCCGCAGAGGCGGCCGGCGCGCTATGATTTCCGGCATCCGCTGCAGAGCGCGTCCCGCAGCTTGCCTTCGCTTGCATC
GCCGGTCCACTCATCGAGCC

Downstream 100 bases:

>100_bases
AGGCAGGAATACGAAAACAACAAGGACATCCACAATGGAACTGACACCGAGAGAGAAGGACAAGCTGCTGATCTTCACTG
CCGCGCTGCTTGCCGAGCGC

Product: urease accessory protein UreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVILHPPAGVAGGDTLDIALHAEA
GTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLPQENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGE
QWNRGVLWLDTQVRCNGHALWIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTC
LSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT

Sequences:

>Translated_289_residues
MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVILHPPAGVAGGDTLDIALHAEA
GTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLPQENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGE
QWNRGVLWLDTQVRCNGHALWIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTC
LSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT
>Mature_289_residues
MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVILHPPAGVAGGDTLDIALHAEA
GTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLPQENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGE
QWNRGVLWLDTQVRCNGHALWIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTC
LSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0829

COG function: function code O; Urease accessory protein UreH

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URED_CUPPJ (Q473R3)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295214.1
- GeneID:   3609192
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0991
- NMPDR:   fig|264198.3.peg.1504
- HOGENOM:   HBG711156
- OMA:   CLGRPVM
- ProtClustDB:   CLSK897186
- BioCyc:   REUT264198:REUT_A0991-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01384
- InterPro:   IPR002669

Pfam domain/function: PF01774 UreD

EC number: NA

Molecular weight: Translated: 31028; Mature: 31028

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVIL
CCCCCCCCCEECCCCCCCEEEEEEECCCCEEEEEEHHCCCCEEEECCCCCCCCCEEEEEE
HPPAGVAGGDTLDIALHAEAGTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLP
ECCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCEEECCC
QENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGEQWNRGVLWLDTQVRCNGHAL
CCCEEECCCHHEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEECCEEE
WIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTC
EEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCHHHHHHH
LSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MRHPDFPSAVAVPPAWQASLRLRFAARGERTVLAARQHRGPLMVQKPLYPEGDICHAVIL
CCCCCCCCCEECCCCCCCEEEEEEECCCCEEEEEEHHCCCCEEEECCCCCCCCCEEEEEE
HPPAGVAGGDTLDIALHAEAGTHAVIATPGATKWYKSLGRDASQHVRLTVEEGARLDWLP
ECCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCEEECCC
QENIVFDDARARIATELSIAPGGSAIGWDAVVLGRQASGEQWNRGVLWLDTQVRCNGHAL
CCCEEECCCHHEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEECCEEE
WIEQSQLDAGSPLRGAVAGLDGMSVLGTLWAVGHGATQELAESLAERLPYAAGLRAGVTC
EEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCHHHHHHH
LSSPAQSMLLVRVLGRQMEAVRHVMVDAWSALREPIHGVPARPLRLWAT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA