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The map label for this gene is cyaD [H]

Identifier: 73540630

GI number: 73540630

Start: 1012565

End: 1013947

Strand: Direct

Name: cyaD [H]

Synonym: Reut_A0927

Alternate gene names: 73540630

Gene position: 1012565-1013947 (Clockwise)

Preceding gene: 73540629

Following gene: 73540631

Centisome position: 26.6

GC content: 66.38

Gene sequence:

>1383_bases
ATGAACGACGCACAAGGCAGCAACCGCCTGAGGCCCCTGTCCGAGGCGCTGGAGGACCACGGCGGCGAAGGCATAGCGAT
CCTTACGGCCGAGCCGTGGCGGCTGAGCCTGCTGACGATCGTGACGACGTTCGCGCTCGTGGTATGCGCGCTGATCTGGT
CGTTCTTCGGACATGCCGATGTGATCGTCACGGCCGAGGGCACGCTGGCGCCGGAGTCGGAAGTCAGGCGCTTCTACGCG
CCCGTGGATGGCGAACTTGCGGACCTGTATGTCGCCGAAGGGCAGCCGGTGTCAAAGGATGACGTGCTGGCCCGCCTGAA
CGCACGCGGCGCCATTGAGGCTGCGGCCAATGCGCTGGAGGCGCAGCTCAAGCTCGAAGACTCGGAGCGCGAATGGAAGC
AGTTCCCCGAGAAGAAGGCGTTAATGGCGCGCCGCGCCGCCGCGCTCAAGCAACAGATCGACGTGGGCACGCGCCAGCAT
GAAACGCGCATTGCCGAAGGCACGACACGGCTGACCGAGCAGCAGCGCGCGCAGATTCAGGAGGCGCGCAGCAATGTCGA
GAATTCGCGCCGTGCCCGAGACTTCGCGCGCCAGGAACAGGACCGCTATACGCGCCTGTTCGCACTGCCGGCCGGCGGCG
GCGTGTCGCAGTCGCAGGTGGATGCCAAGCGCGCGGCCACGCAGGAGGCCGAGAACACGTTGCGCGTGGCGCAATCGCGA
CTGGCCGAACTGGAAGCGCGGCAGGGCCAGGAACTGAGCCAGGCCAACGTGCAGCTCGAAAGCAGCGGCCAGGAACTTGC
TGGCCTGCGCGTGCAGTACGACGCGGCGATGCGAGAGATTGCGAGCACCGAGGACAAGCTGCGCCTGCAGGTGCAGACCG
CGCGTTTAGTGGCCGAGGCAGCTGCGCGCATCCGCTTCGAGAACATCGACAAGGACAACTTCCTGCTGATCCTGGCGCCG
GTGTCAGGCGTTATCACGGACGTGACGTCGACCCAGCGCGGCGACAAGATCCAGGCCAATACGCCGATCGGCGGCATCGC
GCCCAATGACGCGCGCCCCGTGTTGAAGATCGCCATTGCCGAGCGCGACCGCGCGTTCCTGAAGGAGGGCTTGCCAGTCA
AGCTCAAGTTCAACGCGTTCCCATACCAGCGCTACGGCCTGATCGAAGGCACGCTCGAATACATCTCGCCGGCGACCAAG
CCGGGCGGGCCGGACAAGCAGCCGGTCTATGAAGGCCGCATCCGCCTGTCGCGCGATTACTACGCCGTGGGCGAAACCCG
TTACCCACTGCGCTACGGCATGACCGCCACGGCGGAGATCGTCGTGCGCGAGCGCCGCCTGATCGACCTGGGGCTGGACC
CGTTCAGGCAGGTGGCAGGCTAG

Upstream 100 bases:

>100_bases
ACCTGCTTGGCGGCGAAGCGCGGGGCGCAGAAGCGCCGGCTGCCGCGTCGGCTGCAGCGGCGGTCACCGCGGAAACTGAC
AAGCCGAAAGAGGCGCGGCC

Downstream 100 bases:

>100_bases
CGGGACACGGTATTCGGGGAGCGAATCGCGACCGCCGCAGTGCGGCGCTATGGGGATCGGTGCAGGGGCCGTTATAGGAG
GGTAGGGCCATGACTGGCAT

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNDAQGSNRLRPLSEALEDHGGEGIAILTAEPWRLSLLTIVTTFALVVCALIWSFFGHADVIVTAEGTLAPESEVRRFYA
PVDGELADLYVAEGQPVSKDDVLARLNARGAIEAAANALEAQLKLEDSEREWKQFPEKKALMARRAAALKQQIDVGTRQH
ETRIAEGTTRLTEQQRAQIQEARSNVENSRRARDFARQEQDRYTRLFALPAGGGVSQSQVDAKRAATQEAENTLRVAQSR
LAELEARQGQELSQANVQLESSGQELAGLRVQYDAAMREIASTEDKLRLQVQTARLVAEAAARIRFENIDKDNFLLILAP
VSGVITDVTSTQRGDKIQANTPIGGIAPNDARPVLKIAIAERDRAFLKEGLPVKLKFNAFPYQRYGLIEGTLEYISPATK
PGGPDKQPVYEGRIRLSRDYYAVGETRYPLRYGMTATAEIVVRERRLIDLGLDPFRQVAG

Sequences:

>Translated_460_residues
MNDAQGSNRLRPLSEALEDHGGEGIAILTAEPWRLSLLTIVTTFALVVCALIWSFFGHADVIVTAEGTLAPESEVRRFYA
PVDGELADLYVAEGQPVSKDDVLARLNARGAIEAAANALEAQLKLEDSEREWKQFPEKKALMARRAAALKQQIDVGTRQH
ETRIAEGTTRLTEQQRAQIQEARSNVENSRRARDFARQEQDRYTRLFALPAGGGVSQSQVDAKRAATQEAENTLRVAQSR
LAELEARQGQELSQANVQLESSGQELAGLRVQYDAAMREIASTEDKLRLQVQTARLVAEAAARIRFENIDKDNFLLILAP
VSGVITDVTSTQRGDKIQANTPIGGIAPNDARPVLKIAIAERDRAFLKEGLPVKLKFNAFPYQRYGLIEGTLEYISPATK
PGGPDKQPVYEGRIRLSRDYYAVGETRYPLRYGMTATAEIVVRERRLIDLGLDPFRQVAG
>Mature_460_residues
MNDAQGSNRLRPLSEALEDHGGEGIAILTAEPWRLSLLTIVTTFALVVCALIWSFFGHADVIVTAEGTLAPESEVRRFYA
PVDGELADLYVAEGQPVSKDDVLARLNARGAIEAAANALEAQLKLEDSEREWKQFPEKKALMARRAAALKQQIDVGTRQH
ETRIAEGTTRLTEQQRAQIQEARSNVENSRRARDFARQEQDRYTRLFALPAGGGVSQSQVDAKRAATQEAENTLRVAQSR
LAELEARQGQELSQANVQLESSGQELAGLRVQYDAAMREIASTEDKLRLQVQTARLVAEAAARIRFENIDKDNFLLILAP
VSGVITDVTSTQRGDKIQANTPIGGIAPNDARPVLKIAIAERDRAFLKEGLPVKLKFNAFPYQRYGLIEGTLEYISPATK
PGGPDKQPVYEGRIRLSRDYYAVGETRYPLRYGMTATAEIVVRERRLIDLGLDPFRQVAG

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50907; Mature: 50907

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAQGSNRLRPLSEALEDHGGEGIAILTAEPWRLSLLTIVTTFALVVCALIWSFFGHAD
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VIVTAEGTLAPESEVRRFYAPVDGELADLYVAEGQPVSKDDVLARLNARGAIEAAANALE
EEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHH
AQLKLEDSEREWKQFPEKKALMARRAAALKQQIDVGTRQHETRIAEGTTRLTEQQRAQIQ
HHEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EARSNVENSRRARDFARQEQDRYTRLFALPAGGGVSQSQVDAKRAATQEAENTLRVAQSR
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAELEARQGQELSQANVQLESSGQELAGLRVQYDAAMREIASTEDKLRLQVQTARLVAEA
HHHHHHHCCCCHHHHCEEEECCCCHHHCEEEEHHHHHHHHHCCCHHEEEEHHHHHHHHHH
AARIRFENIDKDNFLLILAPVSGVITDVTSTQRGDKIQANTPIGGIAPNDARPVLKIAIA
HHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEEH
ERDRAFLKEGLPVKLKFNAFPYQRYGLIEGTLEYISPATKPGGPDKQPVYEGRIRLSRDY
HHHHHHHHCCCCEEEEECCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCE
YAVGETRYPLRYGMTATAEIVVRERRLIDLGLDPFRQVAG
EEECCCCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MNDAQGSNRLRPLSEALEDHGGEGIAILTAEPWRLSLLTIVTTFALVVCALIWSFFGHAD
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VIVTAEGTLAPESEVRRFYAPVDGELADLYVAEGQPVSKDDVLARLNARGAIEAAANALE
EEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHH
AQLKLEDSEREWKQFPEKKALMARRAAALKQQIDVGTRQHETRIAEGTTRLTEQQRAQIQ
HHEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EARSNVENSRRARDFARQEQDRYTRLFALPAGGGVSQSQVDAKRAATQEAENTLRVAQSR
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAELEARQGQELSQANVQLESSGQELAGLRVQYDAAMREIASTEDKLRLQVQTARLVAEA
HHHHHHHCCCCHHHHCEEEECCCCHHHCEEEEHHHHHHHHHCCCHHEEEEHHHHHHHHHH
AARIRFENIDKDNFLLILAPVSGVITDVTSTQRGDKIQANTPIGGIAPNDARPVLKIAIA
HHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEEH
ERDRAFLKEGLPVKLKFNAFPYQRYGLIEGTLEYISPATKPGGPDKQPVYEGRIRLSRDY
HHHHHHHHCCCCEEEEECCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCE
YAVGETRYPLRYGMTATAEIVVRERRLIDLGLDPFRQVAG
EEECCCCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]