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The map label for this gene is gcp [H]

Identifier: 73540587

GI number: 73540587

Start: 961956

End: 962990

Strand: Reverse

Name: gcp [H]

Synonym: Reut_A0884

Alternate gene names: 73540587

Gene position: 962990-961956 (Counterclockwise)

Preceding gene: 73540595

Following gene: 73540582

Centisome position: 25.3

GC content: 66.76

Gene sequence:

>1035_bases
ATGCTTGTCCTCGGCATCGAATCTTCCTGCGACGAAACCGGCCTGGCCCTCTACGACACCGAGGCCGGCCTGCTCTCGCA
CGCCCTGCATTCGCAGATCGCCATGCACCGTGACTACGGCGGCGTAGTGCCTGAACTGGCCTCGCGCGACCATATTCGCC
GCGTGCTGCCGCTGCTGCAGCAGGTGCTCGATGAAGCGGGCCGCAGCCGCGCGGACATCGACGCCATTGCCTTCACCCAG
GGTCCTGGGCTTGCGGGCGCGCTGCTGGTCGGCGCTTCGGTCGCCAATGCGCTGGGCTTCGCGCTGAACGTGCCGATGGT
GGGTGTCCACCACCTGGAAGGCCACCTGCTGTCGCCGCTGCTTACGCGCGAGCCACCGCCGTTCCCGTTCATCGCCTTGC
TGGTTTCAGGCGGCCACACGCAGCTCATGGAAGTGAAAGGCATCGGCGACTATACGCTGCTCGGCGAAACGCTCGACGAT
GCCGCCGGCGAGGCCTTCGACAAGACCGCCAAGCTGCTCGGCCTCGGTTATCCGGGCGGACCGGAAGTGTCGCGCCTTGC
CGAGTTCGGCACGCCCGGCGCGTTCGACCTCCCCCGGCCGATGCTGCATTCGGGCAACCTCGATTTCTCGTTTGCCGGGC
TCAAGACCGCCGTGCTGACGCAGACGCGCAAGCTCGCCAACACCTGCGAGCAGGACCGCGCCAACCTCGCGCGCGCGTTC
GTCGATGCGATCGTCGATGTGCTCGCTGCGAAGTCCTTTGCCGCGCTCAAGCAGACCGGCCACAAGCGGCTCGTCGTGGC
CGGCGGCGTGGGCGCCAACCGGCAATTGCGCGAACGCCTGAACCAGCTCGGCAAGCAGCGCAAGATCGACGTCTATTACC
CGGACCTTGCGTTCTGCACCGACAACGGCGCGATGATTGCTCTCGCTGGCGCCATGCGGTTGCAGGCAGCACCTGATCTC
GCGCAGCACAGCTACGGCTATGGCGTGACGCCGCGATGGGATCTGGCTGATATCCGCCTGCCTTCGGCCGCCTGA

Upstream 100 bases:

>100_bases
AAAAGCACGCCGGGCGCCGGTGTGCTAACCTGCTGGGTTCCACGCAACCCGTTGTTTTGACGGCTGTTTCGATCCGATCG
GACCGCCGCCCCTGCTTCCC

Downstream 100 bases:

>100_bases
ACATGCCGACGCTGAAAACAGAAAGGCCACCGCGAAGGTGGCCTTTCTGTTTGCACTCAAACCGACTTACGCAGTCGGCT
CAAGCCGTTTGTCGCGTTCA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLVLGIESSCDETGLALYDTEAGLLSHALHSQIAMHRDYGGVVPELASRDHIRRVLPLLQQVLDEAGRSRADIDAIAFTQ
GPGLAGALLVGASVANALGFALNVPMVGVHHLEGHLLSPLLTREPPPFPFIALLVSGGHTQLMEVKGIGDYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPEVSRLAEFGTPGAFDLPRPMLHSGNLDFSFAGLKTAVLTQTRKLANTCEQDRANLARAF
VDAIVDVLAAKSFAALKQTGHKRLVVAGGVGANRQLRERLNQLGKQRKIDVYYPDLAFCTDNGAMIALAGAMRLQAAPDL
AQHSYGYGVTPRWDLADIRLPSAA

Sequences:

>Translated_344_residues
MLVLGIESSCDETGLALYDTEAGLLSHALHSQIAMHRDYGGVVPELASRDHIRRVLPLLQQVLDEAGRSRADIDAIAFTQ
GPGLAGALLVGASVANALGFALNVPMVGVHHLEGHLLSPLLTREPPPFPFIALLVSGGHTQLMEVKGIGDYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPEVSRLAEFGTPGAFDLPRPMLHSGNLDFSFAGLKTAVLTQTRKLANTCEQDRANLARAF
VDAIVDVLAAKSFAALKQTGHKRLVVAGGVGANRQLRERLNQLGKQRKIDVYYPDLAFCTDNGAMIALAGAMRLQAAPDL
AQHSYGYGVTPRWDLADIRLPSAA
>Mature_344_residues
MLVLGIESSCDETGLALYDTEAGLLSHALHSQIAMHRDYGGVVPELASRDHIRRVLPLLQQVLDEAGRSRADIDAIAFTQ
GPGLAGALLVGASVANALGFALNVPMVGVHHLEGHLLSPLLTREPPPFPFIALLVSGGHTQLMEVKGIGDYTLLGETLDD
AAGEAFDKTAKLLGLGYPGGPEVSRLAEFGTPGAFDLPRPMLHSGNLDFSFAGLKTAVLTQTRKLANTCEQDRANLARAF
VDAIVDVLAAKSFAALKQTGHKRLVVAGGVGANRQLRERLNQLGKQRKIDVYYPDLAFCTDNGAMIALAGAMRLQAAPDL
AQHSYGYGVTPRWDLADIRLPSAA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=360, Percent_Identity=35.5555555555556, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI8923380, Length=279, Percent_Identity=31.5412186379928, Blast_Score=131, Evalue=7e-31,
Organism=Escherichia coli, GI1789445, Length=343, Percent_Identity=60.0583090379009, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=31.0030395136778, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=322, Percent_Identity=29.5031055900621, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=357, Percent_Identity=31.9327731092437, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322891, Length=349, Percent_Identity=26.647564469914, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=34.0236686390533, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357207, Length=348, Percent_Identity=28.448275862069, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36528; Mature: 36528

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESSCDETGLALYDTEAGLLSHALHSQIAMHRDYGGVVPELASRDHIRRVLPLLQ
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QVLDEAGRSRADIDAIAFTQGPGLAGALLVGASVANALGFALNVPMVGVHHLEGHLLSPL
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHH
LTREPPPFPFIALLVSGGHTQLMEVKGIGDYTLLGETLDDAAGEAFDKTAKLLGLGYPGG
HHCCCCCCCEEEEEECCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
PEVSRLAEFGTPGAFDLPRPMLHSGNLDFSFAGLKTAVLTQTRKLANTCEQDRANLARAF
CHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAIVDVLAAKSFAALKQTGHKRLVVAGGVGANRQLRERLNQLGKQRKIDVYYPDLAFCT
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEE
DNGAMIALAGAMRLQAAPDLAQHSYGYGVTPRWDLADIRLPSAA
CCCCEEEEEHHHHHHCCCCHHHHCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MLVLGIESSCDETGLALYDTEAGLLSHALHSQIAMHRDYGGVVPELASRDHIRRVLPLLQ
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QVLDEAGRSRADIDAIAFTQGPGLAGALLVGASVANALGFALNVPMVGVHHLEGHLLSPL
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCHHHHHH
LTREPPPFPFIALLVSGGHTQLMEVKGIGDYTLLGETLDDAAGEAFDKTAKLLGLGYPGG
HHCCCCCCCEEEEEECCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
PEVSRLAEFGTPGAFDLPRPMLHSGNLDFSFAGLKTAVLTQTRKLANTCEQDRANLARAF
CHHHHHHHCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAIVDVLAAKSFAALKQTGHKRLVVAGGVGANRQLRERLNQLGKQRKIDVYYPDLAFCT
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEE
DNGAMIALAGAMRLQAAPDLAQHSYGYGVTPRWDLADIRLPSAA
CCCCEEEEEHHHHHHCCCCHHHHCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA