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The map label for this gene is zupT [H]

Identifier: 73540579

GI number: 73540579

Start: 953256

End: 954173

Strand: Direct

Name: zupT [H]

Synonym: Reut_A0876

Alternate gene names: 73540579

Gene position: 953256-954173 (Clockwise)

Preceding gene: 73540578

Following gene: 73540583

Centisome position: 25.04

GC content: 65.58

Gene sequence:

>918_bases
TTGCAACATTGTTGCGTTTGCCGTCCGCACAGCGCCGGGCGGAACCGGCATGCCGCGGATGCGGCACCACCGCCCCGGGA
GCCCATCATCCACTCGACCCTTCTGTACATCCTGCTCGCCGCCACGATTTCCGGCGTGGGCAGCATTTTCGGCGCGGCGC
TGTTGTCGCTGACAATGGCCTCGCGCGTGGTCGAACGCATGGTCAGCTTCTCGGTGGGCGTGCTGCTGGCAACGGCCTTG
CTCCATTCGTTGCCCGAGGCATTCGAGTCGGGTGCCGATCCGCGAGCCTTGTTCGGCACGCTTCTGGCTGGGCTGCTGGG
CTTCTTCCTGCTCGAAAAGATCTCGCTGCTGCGCCACTCGCACCATCACGAGGGCGACGGGCACCACCATCACCACGGCC
ACGACCGTGAAGAAGCGGGCCGCAGCGGCCTGACCATCCTGGTCGGCGACACTTTCCACAACTTTGCCGACGGCATTGTG
ATCGCGGCGGCCTTCCTGGCCGATCCGAACATCGGCATCGTCACGGCGCTGGCCATCGCCGCGCATGAGATTCCGCAGGA
AGTCGGTGATTTCATCGTGCTGCTCAACGCCGGCTTTTCGAAGGCGCGCGCTTTTGCGTTCAACCTGCTGTCGAGCGTCG
CGGCCGTGGCGGGCGGGCTGGTCGGGTACTTCCTGCTGGACCAGATGAGCGGCTGGATTCCCTATGTGCTCGTGATCGCG
TCCAGCAGCTTCCTCTACATCGCCGTGAGCGACCTGATGCCGCAGATGCAGCGCAAGCCGCGCTGGCGCGAATCGGCGAT
TCAGGTGGTGCTCGTGGCGGCCGGCATCACGGCGATCGTCTTCATCACCAATGGCGTCCATGAGCGCCAGGCCCATGGCG
GACACCGCCACGCCACGCGGGCGGTGGCGTCCGACTGA

Upstream 100 bases:

>100_bases
GCTGCGCCAGCACGGCGTCGTCTAACCGTACTCATAGGCGCTGCGCGGACGAGGATTGCAAAGTCCGCGCCGGAATACGT
ACAATGCGGCCTTCCAGTTG

Downstream 100 bases:

>100_bases
GCGGTCTCGGCAGGCTCAGGCTGCAGGTCCCGTGGCGACCGGGCGCGTCGGATCGGCGCACCATTCGCTCCACGAGCCCG
GATAGAGCGCGGCACCTTCC

Product: Zinc transporter ZIP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQHCCVCRPHSAGRNRHAADAAPPPREPIIHSTLLYILLAATISGVGSIFGAALLSLTMASRVVERMVSFSVGVLLATAL
LHSLPEAFESGADPRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIV
IAAAFLADPNIGIVTALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSVAAVAGGLVGYFLLDQMSGWIPYVLVIA
SSSFLYIAVSDLMPQMQRKPRWRESAIQVVLVAAGITAIVFITNGVHERQAHGGHRHATRAVASD

Sequences:

>Translated_305_residues
MQHCCVCRPHSAGRNRHAADAAPPPREPIIHSTLLYILLAATISGVGSIFGAALLSLTMASRVVERMVSFSVGVLLATAL
LHSLPEAFESGADPRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIV
IAAAFLADPNIGIVTALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSVAAVAGGLVGYFLLDQMSGWIPYVLVIA
SSSFLYIAVSDLMPQMQRKPRWRESAIQVVLVAAGITAIVFITNGVHERQAHGGHRHATRAVASD
>Mature_305_residues
MQHCCVCRPHSAGRNRHAADAAPPPREPIIHSTLLYILLAATISGVGSIFGAALLSLTMASRVVERMVSFSVGVLLATAL
LHSLPEAFESGADPRALFGTLLAGLLGFFLLEKISLLRHSHHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIV
IAAAFLADPNIGIVTALAIAAHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSVAAVAGGLVGYFLLDQMSGWIPYVLVIA
SSSFLYIAVSDLMPQMQRKPRWRESAIQVVLVAAGITAIVFITNGVHERQAHGGHRHATRAVASD

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI223633937, Length=261, Percent_Identity=31.8007662835249, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI223633939, Length=298, Percent_Identity=29.8657718120805, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI40255101, Length=300, Percent_Identity=28.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI190014617, Length=307, Percent_Identity=28.6644951140065, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI187936949, Length=128, Percent_Identity=38.28125, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI55741750, Length=128, Percent_Identity=38.28125, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI153252201, Length=131, Percent_Identity=35.8778625954198, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI24586665, Length=161, Percent_Identity=33.5403726708075, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI205830403, Length=161, Percent_Identity=33.5403726708075, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI205830407, Length=160, Percent_Identity=33.75, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI205830424, Length=154, Percent_Identity=33.1168831168831, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI190360568, Length=154, Percent_Identity=33.1168831168831, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI190358541, Length=154, Percent_Identity=33.1168831168831, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI205830405, Length=131, Percent_Identity=34.3511450381679, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI117553619, Length=128, Percent_Identity=35.9375, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI117553608, Length=128, Percent_Identity=35.9375, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI153252214, Length=128, Percent_Identity=35.15625, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI115430255, Length=143, Percent_Identity=37.7622377622378, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI115430259, Length=143, Percent_Identity=37.7622377622378, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI205830426, Length=116, Percent_Identity=37.0689655172414, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI206597541, Length=146, Percent_Identity=33.5616438356164, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI206597539, Length=146, Percent_Identity=33.5616438356164, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789419, Length=197, Percent_Identity=26.3959390862944, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193209531, Length=231, Percent_Identity=30.3030303030303, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71992548, Length=134, Percent_Identity=29.8507462686567, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994730, Length=277, Percent_Identity=23.826714801444, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71998183, Length=168, Percent_Identity=31.547619047619, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538884, Length=109, Percent_Identity=36.697247706422, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566718, Length=145, Percent_Identity=26.2068965517241, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32566720, Length=145, Percent_Identity=26.2068965517241, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322166, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24664383, Length=111, Percent_Identity=43.2432432432432, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161083817, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651189, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651193, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651187, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651191, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651195, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651197, Length=279, Percent_Identity=27.2401433691756, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45549201, Length=111, Percent_Identity=38.7387387387387, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864610, Length=148, Percent_Identity=31.7567567567568, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 32518; Mature: 32518

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHCCVCRPHSAGRNRHAADAAPPPREPIIHSTLLYILLAATISGVGSIFGAALLSLTMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVVERMVSFSVGVLLATALLHSLPEAFESGADPRALFGTLLAGLLGFFLLEKISLLRHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIVIAAAFLADPNIGIVTALAIA
CCCCCCCCCCCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSVAAVAGGLVGYFLLDQMSGWIPYVLVIA
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SSSFLYIAVSDLMPQMQRKPRWRESAIQVVLVAAGITAIVFITNGVHERQAHGGHRHATR
CCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHH
AVASD
HHCCC
>Mature Secondary Structure
MQHCCVCRPHSAGRNRHAADAAPPPREPIIHSTLLYILLAATISGVGSIFGAALLSLTMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVVERMVSFSVGVLLATALLHSLPEAFESGADPRALFGTLLAGLLGFFLLEKISLLRHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHHEGDGHHHHHGHDREEAGRSGLTILVGDTFHNFADGIVIAAAFLADPNIGIVTALAIA
CCCCCCCCCCCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AHEIPQEVGDFIVLLNAGFSKARAFAFNLLSSVAAVAGGLVGYFLLDQMSGWIPYVLVIA
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SSSFLYIAVSDLMPQMQRKPRWRESAIQVVLVAAGITAIVFITNGVHERQAHGGHRHATR
CCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHH
AVASD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA