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The map label for this gene is thrB

Identifier: 73540573

GI number: 73540573

Start: 945136

End: 946128

Strand: Reverse

Name: thrB

Synonym: Reut_A0870

Alternate gene names: 73540573

Gene position: 946128-945136 (Counterclockwise)

Preceding gene: 73540574

Following gene: 73540572

Centisome position: 24.86

GC content: 67.17

Gene sequence:

>993_bases
ATGGCCGTATTCACCACGGTCTCGCACGACGAGATCGCCAGCTGGCTGCTTGACTACGACCTTGGCGAAGTCCGCGAACT
GCGCGGCATCGCCTCCGGCATCGAGAACAGCAACTTCTTTCTGACGACGGAGCAGGATGGCCGCACGCGCGAGTACGTGC
TGACCATCTTCGAGCGCCTCACCTTCGATCAGCTGCCCTACTACCTGCACCTGATGGCGCATCTTGCCACGCGCGGCATC
ACCGTGCCCGCGCCGATCCCGGCGCGCGACGGCGAGATCCTGCGCGCCCTCAAGGGCAAGCCCGCGACTATCGTCACGCG
CCTGCCTGGCGCTTCGCAGCTTGCACCCGACGCCGAGCATTGTGCGGAAGTCGGCGACATGCTCGCGCGCATGCATTTGG
CTGGGCAGGACTACCCGCGCCAGCAGCCGAACCTGCGCAGCCTGCCCTGGTGGCAGCAGACCGAAGCCGAGATCGTGCCT
TTCCTCGATGCGCAGCAACGCACGCTGCTGCAGCAGGAGATCGCGCACCAGGCCGCGTTCTTCGGCAGCGCCGACTATGC
GGCCCTGCCGGGTGGCCCGTGCCACTGCGACCTGTTCCGCGACAATGCGCTGTTCGAAGAGGTCGGGGGCCACCATCGCC
TGGGCGGCTTCTTCGATTTCTACTTCGCCGGCAACGACAAGTGGCTGTTCGACCTGGCAGTGACTGTCAACGACTGGTGC
ATCGACCTGGCCAGCGGCGAGCTGGACAACGCGCGGGCGCATGCCATGGTGCAGGCTTATCACGCGGTCAGGCCGCTCAG
CGCGACGGAAGCCGCGCACTGGCGCGACATGCTGCGCGCGGGCGCGCTGCGCTTCTGGGTGTCGCGCCTGTGGGACTTCT
ACCTGCCGCGGGAAGCCGACATGCTCCAGCCGCACGACCCGACCCATTTCGAACGCATCCTGCGCCGGCGCCTCGCCATG
ACGGCCGATGCCGCCGCGCTTGCCTGGATCTGA

Upstream 100 bases:

>100_bases
GGCCCGGCATGACACCGGGCCGCGCCGGTCCTCCGGCAGTCTTGCCGCGGCGGCGGCCACCCTTGTGCCGCCGCTTTCCG
TTCCGCATCACAAAACGAGT

Downstream 100 bases:

>100_bases
TTGGTATGCAACTACTGGAAGTCCCCGCCAAGGAAGGCTACGTCTGGTTCCGCCAGGGCATCTGGCTGTTCCGCAAGAAT
CCGCTCGCGTTCCTGATGCT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERLTFDQLPYYLHLMAHLATRGI
TVPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEHCAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVP
FLDAQQRTLLQQEIAHQAAFFGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWC
IDLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREADMLQPHDPTHFERILRRRLAM
TADAAALAWI

Sequences:

>Translated_330_residues
MAVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERLTFDQLPYYLHLMAHLATRGI
TVPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEHCAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVP
FLDAQQRTLLQQEIAHQAAFFGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWC
IDLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREADMLQPHDPTHFERILRRRLAM
TADAAALAWI
>Mature_329_residues
AVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERLTFDQLPYYLHLMAHLATRGIT
VPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEHCAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVPF
LDAQQRTLLQQEIAHQAAFFGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWCI
DLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREADMLQPHDPTHFERILRRRLAMT
ADAAALAWI

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_CUPPJ (Q474D4)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295093.1
- ProteinModelPortal:   Q474D4
- SMR:   Q474D4
- GeneID:   3611752
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0870
- NMPDR:   fig|264198.3.peg.1427
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   REUT264198:REUT_A0870-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 37357; Mature: 37226

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERL
CEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHH
TFDQLPYYLHLMAHLATRGITVPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
CAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVPFLDAQQRTLLQQEIAHQAAF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHH
FGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWC
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCE
IDLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREAD
EEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MLQPHDPTHFERILRRRLAMTADAAALAWI
CCCCCCCHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
AVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERL
EEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHH
TFDQLPYYLHLMAHLATRGITVPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
CAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVPFLDAQQRTLLQQEIAHQAAF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHH
FGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWC
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCE
IDLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREAD
EEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MLQPHDPTHFERILRRRLAMTADAAALAWI
CCCCCCCHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA