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The map label for this gene is sucD [H]

Identifier: 73540570

GI number: 73540570

Start: 941846

End: 943312

Strand: Reverse

Name: sucD [H]

Synonym: Reut_A0867

Alternate gene names: 73540570

Gene position: 943312-941846 (Counterclockwise)

Preceding gene: 73540572

Following gene: 73540569

Centisome position: 24.78

GC content: 65.3

Gene sequence:

>1467_bases
ATGAGTGTGCAAATACTGCGTCACCGGCAGTCCAACAATCCCGATTTGTCCCTAGCCGCAACTTGCGATCGCGACCCGGC
TCAGACCGTGGCCGAGGTTGTCGCGCGGGCCAGGCACGCGCAGCGAGAATTCGCGCGTGCCGACCAGGCCACCATCGACA
CCGCCGTGGCTGCGGCCGCCTGGGCGATCATGGAGCCCGCGCGCAACCGCCGGCTCGCCGAATGCGCCGTGGCCGACACG
GGGCTCGGCAATGTCGAGGACAAGATCCGCAAGAACTACCGCAAGACGCTGGGGCTGCTGCGCGATCTGCACGGCCGAAA
GACGGTCGGTGTGATCTTGCAGGATGCGGAAACCGGCATCACCGAAATCGCACGTCCCGTCGGCGTGGTGGCGGCCATCA
CGCCGTCGACGAATCCGGGGGCCACGCCAGCCAACAAGATCATCAACGCGCTCAAGTGCGGCAACAGTGTGATCGTCGCG
CCATCGCCTAAGGGCCAGGGCACGTGCGAGCTGCTGCTGTCGTTCATCCACGCGGAGTTCGCGAAGGCGGGACTGCCGGC
CGATCTCGTGCAGATGCTGCGCTCGCCAGTCTCGAAAGCGGCCACGGCGGAACTGATGCGGCAGGCCGACCTGATCGTCG
CCACCGGCTCGCAGGCCAATGTGCACATGGCCTACACCAGCGGCACGCCAGCGTTCGGCGTGGGTGCGGGCAACGTGGCT
TCGATCATCGACGCCAGCGCCACGCTTGACGATGCCGCGGCGAAGATCGTGCGCTCGAAGACGTTCGACAATGCAACGAG
CTGCTCGTCGGAGAACAGCCTCGTCGTGCTCGATGCCGTCTACAAGCCCATGCTCAGGGCACTGGCTGCGGTCGGTGGCG
TACTGCTCACGTCGACCGAAAAAGCGCGGCTGCAGGCGCTGATGTGGCAGAACGGGAAGCTTGTCGGCGAAGCCACGGGG
CAAAGCGCGCGGCGCATCGCCGAACTGGCGGGACTTGAACGCGTACGCGACCAGCAGCCGACCATGCTGCTCGTCGAGGA
AAGCGGCGTTGGCAGTGACTTCCCGTTCTCGGGAGAAAAGCTCTCGCCCGTGCTCACGCTGTACCGCGCCGCCGACTTTG
CGGCGGCTGTCGACACCGTGTCGCGCCTTTACGACTACATGGGCGCGGGACATTCGGTCAGCTTGCACACTAGCAATCCC
CGTCAGGCACAGCAGCTTGGGCTTGAACTGCCGGTCGCGCGCGTGATCGTCAACCAGGCGCACTGCTTCGCAACGGGTGG
CAACTTTGACAACGGGCTGCCGTTCTCGCTGTCGATGGGCTGCGGCACCTGGGGCGGCAACAACTTCTCGGACAACCTGG
GCTGGCGCCAGTACCTCAATATCACTCGCATTGCCGAACCCATCGCCGAACGCGTGCCCGATGAAGCCGAACTGCTCGGC
GACTACTTCGCGAGGGTCGGCCAATGA

Upstream 100 bases:

>100_bases
GCGGGCTTCACTAGATTCGATCCGGGGCCAGCGCAATCCGCCACACAGCGAGCCACGCGGAAGCCGCCGGACCCCATTGT
CCAAACCGCGGAGTCGATCC

Downstream 100 bases:

>100_bases
ACGCGCGCGTCGAACCCCAAGCCTTCGAAAGCCTGGCCACGGTGATGGCTGCGCGCGCCGCGCAATGGCCGGACCAGCCG
TATCTGCTCTCCCCCGACAG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSVQILRHRQSNNPDLSLAATCDRDPAQTVAEVVARARHAQREFARADQATIDTAVAAAAWAIMEPARNRRLAECAVADT
GLGNVEDKIRKNYRKTLGLLRDLHGRKTVGVILQDAETGITEIARPVGVVAAITPSTNPGATPANKIINALKCGNSVIVA
PSPKGQGTCELLLSFIHAEFAKAGLPADLVQMLRSPVSKAATAELMRQADLIVATGSQANVHMAYTSGTPAFGVGAGNVA
SIIDASATLDDAAAKIVRSKTFDNATSCSSENSLVVLDAVYKPMLRALAAVGGVLLTSTEKARLQALMWQNGKLVGEATG
QSARRIAELAGLERVRDQQPTMLLVEESGVGSDFPFSGEKLSPVLTLYRAADFAAAVDTVSRLYDYMGAGHSVSLHTSNP
RQAQQLGLELPVARVIVNQAHCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAEPIAERVPDEAELLG
DYFARVGQ

Sequences:

>Translated_488_residues
MSVQILRHRQSNNPDLSLAATCDRDPAQTVAEVVARARHAQREFARADQATIDTAVAAAAWAIMEPARNRRLAECAVADT
GLGNVEDKIRKNYRKTLGLLRDLHGRKTVGVILQDAETGITEIARPVGVVAAITPSTNPGATPANKIINALKCGNSVIVA
PSPKGQGTCELLLSFIHAEFAKAGLPADLVQMLRSPVSKAATAELMRQADLIVATGSQANVHMAYTSGTPAFGVGAGNVA
SIIDASATLDDAAAKIVRSKTFDNATSCSSENSLVVLDAVYKPMLRALAAVGGVLLTSTEKARLQALMWQNGKLVGEATG
QSARRIAELAGLERVRDQQPTMLLVEESGVGSDFPFSGEKLSPVLTLYRAADFAAAVDTVSRLYDYMGAGHSVSLHTSNP
RQAQQLGLELPVARVIVNQAHCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAEPIAERVPDEAELLG
DYFARVGQ
>Mature_487_residues
SVQILRHRQSNNPDLSLAATCDRDPAQTVAEVVARARHAQREFARADQATIDTAVAAAAWAIMEPARNRRLAECAVADTG
LGNVEDKIRKNYRKTLGLLRDLHGRKTVGVILQDAETGITEIARPVGVVAAITPSTNPGATPANKIINALKCGNSVIVAP
SPKGQGTCELLLSFIHAEFAKAGLPADLVQMLRSPVSKAATAELMRQADLIVATGSQANVHMAYTSGTPAFGVGAGNVAS
IIDASATLDDAAAKIVRSKTFDNATSCSSENSLVVLDAVYKPMLRALAAVGGVLLTSTEKARLQALMWQNGKLVGEATGQ
SARRIAELAGLERVRDQQPTMLLVEESGVGSDFPFSGEKLSPVLTLYRAADFAAAVDTVSRLYDYMGAGHSVSLHTSNPR
QAQQLGLELPVARVIVNQAHCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAEPIAERVPDEAELLGD
YFARVGQ

Specific function: Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787493, Length=440, Percent_Identity=36.8181818181818, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788797, Length=365, Percent_Identity=31.2328767123288, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.76 [H]

Molecular weight: Translated: 51757; Mature: 51626

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQILRHRQSNNPDLSLAATCDRDPAQTVAEVVARARHAQREFARADQATIDTAVAAAA
CCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIMEPARNRRLAECAVADTGLGNVEDKIRKNYRKTLGLLRDLHGRKTVGVILQDAETGI
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
TEIARPVGVVAAITPSTNPGATPANKIINALKCGNSVIVAPSPKGQGTCELLLSFIHAEF
HHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
AKAGLPADLVQMLRSPVSKAATAELMRQADLIVATGSQANVHMAYTSGTPAFGVGAGNVA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCCHH
SIIDASATLDDAAAKIVRSKTFDNATSCSSENSLVVLDAVYKPMLRALAAVGGVLLTSTE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEECCH
KARLQALMWQNGKLVGEATGQSARRIAELAGLERVRDQQPTMLLVEESGVGSDFPFSGEK
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCH
LSPVLTLYRAADFAAAVDTVSRLYDYMGAGHSVSLHTSNPRQAQQLGLELPVARVIVNQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHHH
HCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAEPIAERVPDEAELLG
HEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
DYFARVGQ
HHHHHHCC
>Mature Secondary Structure 
SVQILRHRQSNNPDLSLAATCDRDPAQTVAEVVARARHAQREFARADQATIDTAVAAAA
CCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIMEPARNRRLAECAVADTGLGNVEDKIRKNYRKTLGLLRDLHGRKTVGVILQDAETGI
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
TEIARPVGVVAAITPSTNPGATPANKIINALKCGNSVIVAPSPKGQGTCELLLSFIHAEF
HHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
AKAGLPADLVQMLRSPVSKAATAELMRQADLIVATGSQANVHMAYTSGTPAFGVGAGNVA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCCHH
SIIDASATLDDAAAKIVRSKTFDNATSCSSENSLVVLDAVYKPMLRALAAVGGVLLTSTE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEECCH
KARLQALMWQNGKLVGEATGQSARRIAELAGLERVRDQQPTMLLVEESGVGSDFPFSGEK
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCH
LSPVLTLYRAADFAAAVDTVSRLYDYMGAGHSVSLHTSNPRQAQQLGLELPVARVIVNQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHHH
HCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAEPIAERVPDEAELLG
HEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
DYFARVGQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]