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The map label for this gene is kynB

Identifier: 73540512

GI number: 73540512

Start: 879332

End: 879991

Strand: Reverse

Name: kynB

Synonym: Reut_A0809

Alternate gene names: 73540512

Gene position: 879991-879332 (Counterclockwise)

Preceding gene: 73540514

Following gene: 73540511

Centisome position: 23.12

GC content: 67.88

Gene sequence:

>660_bases
ATGACCAACCGCCCCGCAACGCCCGCCGACAGCCGCAAGCTGTGGGACATCAGCCCCCCGCTTTCCCCCGCCACGCCCGT
GTGGCCCGGCGACACGCCGTTCCAACAGGAAACCGCTTGGCAGATGGATGAGCACTGCCCGGTCAATGTCGGCCGCATCA
CGCTGTCGCCGCATACCGGCGCCCATGCCGACGCGCCGCTGCACTATGCCGCTGATGGGGCGCCGATCGGCGAAGTTGGC
CTGGAACCGTACCTTGGCCGTTGCCGCGTGATCCATTGCGTGGGTGCCACGCCCGTCGTCGCACCACATCACGTGGAACA
TGCGCTGAACGACCTGCCGACGCGCGTGCTGCTGCGCACGTACAAACGCGCGCCGCTCGATCAATGGGACACCGGTTTCT
GCGCCGTCGCCCCCGAAACCATTGCACTGCTTGCCGCGCACGGCGTGCAGCTGATCGGCATCGACACGCCGTCGCTGGAC
CCGCAGGAGTCCAAGACCATGGACGCGCACAAGGCCGTGCGCCGCCACGGGCTGGCCATTCTCGAAGGCCTGGTGCTCGA
TGCCGTCGCCGAAGGCGACTACGAACTCATTGCGCTGCCGCTGCGCTTTACCGGGCTCGACGCAAGCCCGGTGCGTGCCG
TGCTGCGCAGCCTTGACTGA

Upstream 100 bases:

>100_bases
CATTCAGCAGTGGATTTCGCAAGCCTCTTGCCGGTTTTTTTGACTATCATGCCGTCATCGAGGACGACATCGACGCCGCC
CCTGCGGCAGCCGTGCAGAC

Downstream 100 bases:

>100_bases
ACACCCCCCGTAATCCTTTGCCTCTTTCCGACATGACTGCACTGACCCGCGAGCAATGCCTGTTGCTCGACCAGCAAGAC
CCCCTGCGCGCATTGCGCGA

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTNRPATPADSRKLWDISPPLSPATPVWPGDTPFQQETAWQMDEHCPVNVGRITLSPHTGAHADAPLHYAADGAPIGEVG
LEPYLGRCRVIHCVGATPVVAPHHVEHALNDLPTRVLLRTYKRAPLDQWDTGFCAVAPETIALLAAHGVQLIGIDTPSLD
PQESKTMDAHKAVRRHGLAILEGLVLDAVAEGDYELIALPLRFTGLDASPVRAVLRSLD

Sequences:

>Translated_219_residues
MTNRPATPADSRKLWDISPPLSPATPVWPGDTPFQQETAWQMDEHCPVNVGRITLSPHTGAHADAPLHYAADGAPIGEVG
LEPYLGRCRVIHCVGATPVVAPHHVEHALNDLPTRVLLRTYKRAPLDQWDTGFCAVAPETIALLAAHGVQLIGIDTPSLD
PQESKTMDAHKAVRRHGLAILEGLVLDAVAEGDYELIALPLRFTGLDASPVRAVLRSLD
>Mature_218_residues
TNRPATPADSRKLWDISPPLSPATPVWPGDTPFQQETAWQMDEHCPVNVGRITLSPHTGAHADAPLHYAADGAPIGEVGL
EPYLGRCRVIHCVGATPVVAPHHVEHALNDLPTRVLLRTYKRAPLDQWDTGFCAVAPETIALLAAHGVQLIGIDTPSLDP
QESKTMDAHKAVRRHGLAILEGLVLDAVAEGDYELIALPLRFTGLDASPVRAVLRSLD

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_CUPPJ (Q474J5)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295032.1
- ProteinModelPortal:   Q474J5
- SMR:   Q474J5
- GeneID:   3610803
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0809
- NMPDR:   fig|264198.3.peg.1322
- HOGENOM:   HBG686791
- OMA:   CPVNVGR
- ProtClustDB:   CLSK769116
- BioCyc:   REUT264198:REUT_A0809-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 23616; Mature: 23485

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRPATPADSRKLWDISPPLSPATPVWPGDTPFQQETAWQMDEHCPVNVGRITLSPHTG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCC
AHADAPLHYAADGAPIGEVGLEPYLGRCRVIHCVGATPVVAPHHVEHALNDLPTRVLLRT
CCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHH
YKRAPLDQWDTGFCAVAPETIALLAAHGVQLIGIDTPSLDPQESKTMDAHKAVRRHGLAI
HHCCCCCCCCCCEEEECHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LEGLVLDAVAEGDYELIALPLRFTGLDASPVRAVLRSLD
HHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
TNRPATPADSRKLWDISPPLSPATPVWPGDTPFQQETAWQMDEHCPVNVGRITLSPHTG
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCC
AHADAPLHYAADGAPIGEVGLEPYLGRCRVIHCVGATPVVAPHHVEHALNDLPTRVLLRT
CCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHH
YKRAPLDQWDTGFCAVAPETIALLAAHGVQLIGIDTPSLDPQESKTMDAHKAVRRHGLAI
HHCCCCCCCCCCEEEECHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LEGLVLDAVAEGDYELIALPLRFTGLDASPVRAVLRSLD
HHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA