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The map label for this gene is queC [H]

Identifier: 73540502

GI number: 73540502

Start: 867462

End: 868142

Strand: Direct

Name: queC [H]

Synonym: Reut_A0798

Alternate gene names: 73540502

Gene position: 867462-868142 (Clockwise)

Preceding gene: 73540501

Following gene: 73540503

Centisome position: 22.79

GC content: 65.2

Gene sequence:

>681_bases
ATGACCAAACGCGCCATTGTCCTGCTTTCGGGCGGGCTTGATTCCGCCACCGTTCTTGCCATGGCCAAGGCCCAGGGCTT
CGAGACCTATGCGCTGTCGATGCGCTATGGCCAGCGCCATTCTTCCGAGCTTGATGCGGCCAAACAGGTCGCCAGCGCGC
TCGGCGCCGTGCGCCACGAAATCGTCGACCTGGACCTGCGCCGCTTCGGTGGCTCCGCGCTGACCGACGACAAGCTCGAC
GTGCCGACCGGCGGCGCGTCGTCGGGTATTCCAATCACCTACGTGCCAGCGCGCAACACCATCATGCTGTCGCTGGCACT
CGGCTGGGCCGAAGCCGTTGGCGGGCGCGACCTGTTCTTCGGTGCGAACGCCGTGGACTACTCGGGCTATCCTGATTGCC
GTCCCGAATACGTCGCAGCCTACGAGACGCTGGCCAACCTCGCCACCAAGGCCGGCGTGGAGGGTGACCGCTTCCATGTG
CATGCGCCGATCATCGACATGACCAAGGCCGAGATCATCCGCGCGGGTATTCGCCTCGGTGTCGATTACAGCATGACGGT
GTCATGCTACAAGGCCGACGACGACGGCCGCGCCTGCGGCGTCTGCGATTCCTGCCGTATCCGCCGCGCCGGCTTCGAAG
CAGCCGGTGTTCCCGACCCGACTCGTTACCAGAACGCCTGA

Upstream 100 bases:

>100_bases
ACTGCAAAGCCCGCGTTCAGCGGGCTTTTTTCCGTCTCGCGCTAAAATACGCGATTCGCCTGCAATTTTCGCGTGCCGCC
TGCGCGGCGCGACTGCCATC

Downstream 100 bases:

>100_bases
GCAGCCCCCAGCTTTTTCTTCATCGCCCCCGACATGCCCGAGATCGATATCGCCGCGCTTTCGCGCACCGTGCTGCTGAG
CACTTTTGTCCTGACCTTCC

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTKRAIVLLSGGLDSATVLAMAKAQGFETYALSMRYGQRHSSELDAAKQVASALGAVRHEIVDLDLRRFGGSALTDDKLD
VPTGGASSGIPITYVPARNTIMLSLALGWAEAVGGRDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDRFHV
HAPIIDMTKAEIIRAGIRLGVDYSMTVSCYKADDDGRACGVCDSCRIRRAGFEAAGVPDPTRYQNA

Sequences:

>Translated_226_residues
MTKRAIVLLSGGLDSATVLAMAKAQGFETYALSMRYGQRHSSELDAAKQVASALGAVRHEIVDLDLRRFGGSALTDDKLD
VPTGGASSGIPITYVPARNTIMLSLALGWAEAVGGRDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDRFHV
HAPIIDMTKAEIIRAGIRLGVDYSMTVSCYKADDDGRACGVCDSCRIRRAGFEAAGVPDPTRYQNA
>Mature_225_residues
TKRAIVLLSGGLDSATVLAMAKAQGFETYALSMRYGQRHSSELDAAKQVASALGAVRHEIVDLDLRRFGGSALTDDKLDV
PTGGASSGIPITYVPARNTIMLSLALGWAEAVGGRDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDRFHVH
APIIDMTKAEIIRAGIRLGVDYSMTVSCYKADDDGRACGVCDSCRIRRAGFEAAGVPDPTRYQNA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=225, Percent_Identity=36.8888888888889, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24060; Mature: 23929

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRAIVLLSGGLDSATVLAMAKAQGFETYALSMRYGQRHSSELDAAKQVASALGAVRHE
CCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHH
IVDLDLRRFGGSALTDDKLDVPTGGASSGIPITYVPARNTIMLSLALGWAEAVGGRDLFF
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCCEEEE
GANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDRFHVHAPIIDMTKAEIIRAGIRLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VDYSMTVSCYKADDDGRACGVCDSCRIRRAGFEAAGVPDPTRYQNA
CCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKRAIVLLSGGLDSATVLAMAKAQGFETYALSMRYGQRHSSELDAAKQVASALGAVRHE
CCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHH
IVDLDLRRFGGSALTDDKLDVPTGGASSGIPITYVPARNTIMLSLALGWAEAVGGRDLFF
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCCEEEE
GANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDRFHVHAPIIDMTKAEIIRAGIRLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VDYSMTVSCYKADDDGRACGVCDSCRIRRAGFEAAGVPDPTRYQNA
CCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA