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The map label for this gene is nrdR [H]

Identifier: 73540493

GI number: 73540493

Start: 859532

End: 859996

Strand: Reverse

Name: nrdR [H]

Synonym: Reut_A0789

Alternate gene names: 73540493

Gene position: 859996-859532 (Counterclockwise)

Preceding gene: 73540494

Following gene: 73540486

Centisome position: 22.59

GC content: 60.43

Gene sequence:

>465_bases
ATGAAATGCCCCTTTTGCGGACATTCCAATACCCAGGTGCTCGACACCCGCATGTCGGAAGACGGCGATGCCGTACGCCG
GCGCCGGCGCTGCGAAGCCTGCGACCGCCGCTTCACCACTTACGAGCGGATCGAACTATTCTTTCCGGCCATCGTCAAGA
AGAACGGCTCGCGCGTGGACTACAGCCGCGCCAAGCTGAAGGATTCCATGCGCCTGGCGCTGCGCAAGCGCCCCGTGTCG
GCTGAAGCCATCGACGAGGCCATTACCCGCATCGAAGAAAAGCTGCTCGCGCTCGGCCAGAAGGAAATTCCCAGCAGCCA
GGTCGGTGAACTGGTCATGCGCGAACTGCGCAAGCTCGACAAGATCGCCTATATCCGGTTTGCTTCCGTGTATCGGAGCT
TTGAGGATGTCGCCGAGTTTTCCGATGTGCTGGCCGAGGTGACGTCAGGGAATAGCAAGCGCTAG

Upstream 100 bases:

>100_bases
GGCGCGCCACCGCGCCGCTTGCGGGCCTCGCCAACCTGCCCTATGCCATAGAAGGACAAGATACCAAGGCGGCCGGGCTC
AATTCTGAAGGTGGTCAGGC

Downstream 100 bases:

>100_bases
AGCGTGGCCGCCCCCTCGGCGTCAGCGCTCCCAGCAATTCTGCAGGTACGCCGCCGGGTTCGCGCCAACGGTATTCAGAC
GCGTGCCGGCCTGATCCAGC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYSRAKLKDSMRLALRKRPVS
AEAIDEAITRIEEKLLALGQKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVAEFSDVLAEVTSGNSKR

Sequences:

>Translated_154_residues
MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYSRAKLKDSMRLALRKRPVS
AEAIDEAITRIEEKLLALGQKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVAEFSDVLAEVTSGNSKR
>Mature_154_residues
MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYSRAKLKDSMRLALRKRPVS
AEAIDEAITRIEEKLLALGQKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVAEFSDVLAEVTSGNSKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=145, Percent_Identity=51.0344827586207, Blast_Score=159, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17742; Mature: 17742

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVD
CCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YSRAKLKDSMRLALRKRPVSAEAIDEAITRIEEKLLALGQKEIPSSQVGELVMRELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KIAYIRFASVYRSFEDVAEFSDVLAEVTSGNSKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVD
CCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YSRAKLKDSMRLALRKRPVSAEAIDEAITRIEEKLLALGQKEIPSSQVGELVMRELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
KIAYIRFASVYRSFEDVAEFSDVLAEVTSGNSKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA