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The map label for this gene is ompR [H]

Identifier: 73540279

GI number: 73540279

Start: 625866

End: 626597

Strand: Direct

Name: ompR [H]

Synonym: Reut_A0573

Alternate gene names: 73540279

Gene position: 625866-626597 (Clockwise)

Preceding gene: 73540273

Following gene: 73540280

Centisome position: 16.44

GC content: 64.75

Gene sequence:

>732_bases
ATGCGAACGAACCAGCCCACCCAGATCCTTGTCGTCGACGACGACCCTGAATTGCGCGATCTGCTGCGCGAGTACCTGAC
CCAGCAAGGGTTTGCGGTCTCGGTACTGCACGATGGCGATGGCCTGCAGGCGCGCCTCGAGCGCGAGCGCCCGGCGCTGA
TCGTGCTGGACCTGATGATGCCGAAGGTCGATGGACTGACTGCACTGCGCAATCTGCGTGCCAAGAACGACGACATTCCG
GTGATCCTTTTGACCGCGCGCAGCGACGAGATCGACCGCATCGTCGGCCTCGAGATCGGCGCCGACGATTACCTTGGCAA
GCCGTTTTCGCCACGCGAGCTGCTCGCGCGCATCAATGCCGTGCTGCGCCGCAAGCTCGCACGGCCGGCGGCCGCACCGG
AAGACCGCGAATCGATCGCGTTCGGGCCGTTCCGCGTGAACTTCCGCCAGCGCTCGCTGCAGCGAGCGGGCCAGGTGCTG
TCGATCAGCGACACAGAATTCGCGCTGCTCAAGCTGCTGCTGATGCATCCGCTCGAAGTGCTCTCGCGCGAGCGCATTGT
CGAGCTGATGTATGGCACCGCCAGCGGCATCAGCGACCGCGGCATCGATGTGCAGATCTGGCGCTTGCGCCGGCTGCTCG
ACGAAGACGCTCAGCGCCCGCGCTACATCCAGACCGTGCGCGGACGCGGCTACACGTTCGTACCGGACGAAGCCGAAGAA
ATTCCGCAGTAA

Upstream 100 bases:

>100_bases
TTTATTACAGAGAATTACCAGCCCCGCCTGTGTAATCTCCAGAAACAAAGCCGCGAGCCGGATTCGGCAGGACAGCGGCC
AGCCTGACTATCATGTGCCT

Downstream 100 bases:

>100_bases
CGCCTGTCGCCTCTGTCGCCCGTCCGGCGGCAGGGCGGCAATGACGAGTCCTGACATGAAGTTGCGTATTGATACCCTGT
TTGGCCGCATAGCACTGCTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRTNQPTQILVVDDDPELRDLLREYLTQQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESIAFGPFRVNFRQRSLQRAGQVL
SISDTEFALLKLLLMHPLEVLSRERIVELMYGTASGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAEE
IPQ

Sequences:

>Translated_243_residues
MRTNQPTQILVVDDDPELRDLLREYLTQQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESIAFGPFRVNFRQRSLQRAGQVL
SISDTEFALLKLLLMHPLEVLSRERIVELMYGTASGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAEE
IPQ
>Mature_243_residues
MRTNQPTQILVVDDDPELRDLLREYLTQQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESIAFGPFRVNFRQRSLQRAGQVL
SISDTEFALLKLLLMHPLEVLSRERIVELMYGTASGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAEE
IPQ

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=51.7391304347826, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=39.4957983193277, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=40.3508771929825, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=41.991341991342, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=36.9098712446352, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=36.5638766519824, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=37.6623376623377, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=32.3404255319149, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=34.3096234309623, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=34.6320346320346, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=35.5263157894737, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.070796460177, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.3478260869565, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=31.2977099236641, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=32.7272727272727, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790437, Length=153, Percent_Identity=26.797385620915, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=33.9805825242718, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27674; Mature: 27674

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNQPTQILVVDDDPELRDLLREYLTQQGFAVSVLHDGDGLQARLERERPALIVLDLMM
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCEEEEEEHHH
PKVDGLTALRNLRAKNDDIPVILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINA
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHHHH
VLRRKLARPAAAPEDRESIAFGPFRVNFRQRSLQRAGQVLSISDTEFALLKLLLMHPLEV
HHHHHHHCCCCCCCCCCCEEECCEEECHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
LSRERIVELMYGTASGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAEE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCHHH
IPQ
CCC
>Mature Secondary Structure
MRTNQPTQILVVDDDPELRDLLREYLTQQGFAVSVLHDGDGLQARLERERPALIVLDLMM
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCEEEEEEHHH
PKVDGLTALRNLRAKNDDIPVILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINA
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHHHH
VLRRKLARPAAAPEDRESIAFGPFRVNFRQRSLQRAGQVLSISDTEFALLKLLLMHPLEV
HHHHHHHCCCCCCCCCCCEEECCEEECHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
LSRERIVELMYGTASGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAEE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCHHH
IPQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]