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The map label for this gene is yhcK [H]

Identifier: 73540245

GI number: 73540245

Start: 585116

End: 586414

Strand: Direct

Name: yhcK [H]

Synonym: Reut_A0539

Alternate gene names: 73540245

Gene position: 585116-586414 (Clockwise)

Preceding gene: 73540240

Following gene: 73540247

Centisome position: 15.37

GC content: 61.2

Gene sequence:

>1299_bases
ATGTTCGAGGGCGGTCCACACCTTGATCGAAGTCGCCTTACATGGCAAGGCAGCCGCAGAACTGCCTGCATTACCTTGAA
TCTCGATTCCATCCCTGAATTCGCGATCGATCCGCTGCGTCTGGAGTTCCGAAGCGCGGAAACGGAACTGGCGTTCCAGC
ACCACCATCTGGATCGCAGTCGGGCGAGCCTGCGCCTGACACTGATTTTCTGCTCCGTCTTCTATCTGGCCTTTGCCATG
ACGGATGTGGCGGTGCTGGGCTATGGACGCGAGGCGCTGATCCTGTTCGCCGCGCGCATGCTGGTCGCGATCACCGCAAC
CATGGGCTTGTTCCTGATCCGCAACCAGCAGGAGCCCATTGCGGGCCTGTGGTTCGTTGCCAGTGCCGCCGAGGTGGTGG
GCATGGCCACCTTCATGCTTATCGTCTGGTACCGCCCCAGTGAAATTCCATGGCATGGGATGTCGCTGTGCATCATGCTG
ATCGTCGTCTACATCTTCATCCCTAACCGGCTGATCATCGCGAAGGGCATCGCGATTGCCTCGACGGCGGCGTTCGTTCT
CGTCGCGTTGGAGAAAGGAACCGGAACCGGCCCGCCCGCCGGTACGCTGACCATGTCGATGCTATTGCTGCTTGCCAACA
GCTTCGGGCTCGTAGCAGCGCGTCGTTACCATCGCCTGTGGCGAGACGAATATCGCGTCCTCATGGACCTGAAGCAGGTG
TCCCTGAGAGACCATCTGACCGATTGCTACAACCGACGCCATCTGCATGAGACGCTGCTCCCCACGGAAATCGCGAGTGC
GCGCCGGTATCAGCACTGGCTGACCATGGTGGTCTGTGACATTGACCACTTCAAGTCGATCAACGACACGCATGGCCACC
AGTCCGGTGACGCCGTGCTGCAGCACATCGCGGCCGTTCTCCGGGCCACCACCCGCAGGCACGTGGACAGCGTGGTCCGC
TATGGCGGCGAAGAATTCCTGCTGCTCCTGCCGCAAACGGGCCCGGACGGTGCCTCGTATGTGGCGGAGCGGCTCAGGAC
TTCGATCGCGGGCAGTCCGACGATCGATGGCGCTGGCCGAAGCATCGAAGCGACGGCCAGCTTTGGAGTGCTGGCGGTCG
ATTTCTCGTCCGTTGGAAGTGATGTCACCGAAACGTCGTTGATCGCAGCCGCCGATGCGTTGCTTTACGAAGCCAAGGCA
TCCGGCCGGAACAGCATCCGCTTCCGGGAATGGCCCGGCAAATCGCGGGAACAGGACGTCGATGTTCTTGTGCTGGCTGC
CTCTGATGCGCCGGGATGA

Upstream 100 bases:

>100_bases
TCCCCCGTCGTGCATGTCCAATGATACAAACATGGATTGATGGATACTTTCCATGGCATCCGGAAAATCCCACGCCGCTG
AAAGCGTCGAGTTCAGCGGC

Downstream 100 bases:

>100_bases
CGCCGTGGCCGCCGGCCCGGGCAGACACAGGCTTATGGAACCATTAGCCGGCCGGTGTGGAAACCCAATCCCCCGACTTC
CCGCCGTGCTTCTCCAGCAG

Product: GGDEF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MFEGGPHLDRSRLTWQGSRRTACITLNLDSIPEFAIDPLRLEFRSAETELAFQHHHLDRSRASLRLTLIFCSVFYLAFAM
TDVAVLGYGREALILFAARMLVAITATMGLFLIRNQQEPIAGLWFVASAAEVVGMATFMLIVWYRPSEIPWHGMSLCIML
IVVYIFIPNRLIIAKGIAIASTAAFVLVALEKGTGTGPPAGTLTMSMLLLLANSFGLVAARRYHRLWRDEYRVLMDLKQV
SLRDHLTDCYNRRHLHETLLPTEIASARRYQHWLTMVVCDIDHFKSINDTHGHQSGDAVLQHIAAVLRATTRRHVDSVVR
YGGEEFLLLLPQTGPDGASYVAERLRTSIAGSPTIDGAGRSIEATASFGVLAVDFSSVGSDVTETSLIAAADALLYEAKA
SGRNSIRFREWPGKSREQDVDVLVLAASDAPG

Sequences:

>Translated_432_residues
MFEGGPHLDRSRLTWQGSRRTACITLNLDSIPEFAIDPLRLEFRSAETELAFQHHHLDRSRASLRLTLIFCSVFYLAFAM
TDVAVLGYGREALILFAARMLVAITATMGLFLIRNQQEPIAGLWFVASAAEVVGMATFMLIVWYRPSEIPWHGMSLCIML
IVVYIFIPNRLIIAKGIAIASTAAFVLVALEKGTGTGPPAGTLTMSMLLLLANSFGLVAARRYHRLWRDEYRVLMDLKQV
SLRDHLTDCYNRRHLHETLLPTEIASARRYQHWLTMVVCDIDHFKSINDTHGHQSGDAVLQHIAAVLRATTRRHVDSVVR
YGGEEFLLLLPQTGPDGASYVAERLRTSIAGSPTIDGAGRSIEATASFGVLAVDFSSVGSDVTETSLIAAADALLYEAKA
SGRNSIRFREWPGKSREQDVDVLVLAASDAPG
>Mature_432_residues
MFEGGPHLDRSRLTWQGSRRTACITLNLDSIPEFAIDPLRLEFRSAETELAFQHHHLDRSRASLRLTLIFCSVFYLAFAM
TDVAVLGYGREALILFAARMLVAITATMGLFLIRNQQEPIAGLWFVASAAEVVGMATFMLIVWYRPSEIPWHGMSLCIML
IVVYIFIPNRLIIAKGIAIASTAAFVLVALEKGTGTGPPAGTLTMSMLLLLANSFGLVAARRYHRLWRDEYRVLMDLKQV
SLRDHLTDCYNRRHLHETLLPTEIASARRYQHWLTMVVCDIDHFKSINDTHGHQSGDAVLQHIAAVLRATTRRHVDSVVR
YGGEEFLLLLPQTGPDGASYVAERLRTSIAGSPTIDGAGRSIEATASFGVLAVDFSSVGSDVTETSLIAAADALLYEAKA
SGRNSIRFREWPGKSREQDVDVLVLAASDAPG

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=208, Percent_Identity=33.1730769230769, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787802, Length=187, Percent_Identity=34.7593582887701, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=35.5828220858896, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=238, Percent_Identity=31.0924369747899, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=32.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=34.8314606741573, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=29.1208791208791, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787816, Length=135, Percent_Identity=34.8148148148148, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=31.5151515151515, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=179, Percent_Identity=26.8156424581006, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 47741; Mature: 47741

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGGPHLDRSRLTWQGSRRTACITLNLDSIPEFAIDPLRLEFRSAETELAFQHHHLDRS
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCHHEEECCCCHHHHHHHHHCCCH
RASLRLTLIFCSVFYLAFAMTDVAVLGYGREALILFAARMLVAITATMGLFLIRNQQEPI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
AGLWFVASAAEVVGMATFMLIVWYRPSEIPWHGMSLCIMLIVVYIFIPNRLIIAKGIAIA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHH
STAAFVLVALEKGTGTGPPAGTLTMSMLLLLANSFGLVAARRYHRLWRDEYRVLMDLKQV
HHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLRDHLTDCYNRRHLHETLLPTEIASARRYQHWLTMVVCDIDHFKSINDTHGHQSGDAVL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECHHHHCCCCCCCCCCCHHHHH
QHIAAVLRATTRRHVDSVVRYGGEEFLLLLPQTGPDGASYVAERLRTSIAGSPTIDGAGR
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SIEATASFGVLAVDFSSVGSDVTETSLIAAADALLYEAKASGRNSIRFREWPGKSREQDV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC
DVLVLAASDAPG
CEEEEEECCCCC
>Mature Secondary Structure
MFEGGPHLDRSRLTWQGSRRTACITLNLDSIPEFAIDPLRLEFRSAETELAFQHHHLDRS
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCHHEEECCCCHHHHHHHHHCCCH
RASLRLTLIFCSVFYLAFAMTDVAVLGYGREALILFAARMLVAITATMGLFLIRNQQEPI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
AGLWFVASAAEVVGMATFMLIVWYRPSEIPWHGMSLCIMLIVVYIFIPNRLIIAKGIAIA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHH
STAAFVLVALEKGTGTGPPAGTLTMSMLLLLANSFGLVAARRYHRLWRDEYRVLMDLKQV
HHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLRDHLTDCYNRRHLHETLLPTEIASARRYQHWLTMVVCDIDHFKSINDTHGHQSGDAVL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECHHHHCCCCCCCCCCCHHHHH
QHIAAVLRATTRRHVDSVVRYGGEEFLLLLPQTGPDGASYVAERLRTSIAGSPTIDGAGR
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SIEATASFGVLAVDFSSVGSDVTETSLIAAADALLYEAKASGRNSIRFREWPGKSREQDV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC
DVLVLAASDAPG
CEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]