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The map label for this gene is rtcB [H]

Identifier: 73539689

GI number: 73539689

Start: 2708279

End: 2709508

Strand: Direct

Name: rtcB [H]

Synonym: Reut_B5869

Alternate gene names: 73539689

Gene position: 2708279-2709508 (Clockwise)

Preceding gene: 73539688

Following gene: 73539690

Centisome position: 99.34

GC content: 65.93

Gene sequence:

>1230_bases
ATGACGCAACAGGCCCGCTACGAACTGCTGAAGACCGACAAGGGCCGCCCGGTCAAGATGTGGACCCGCGGCGTGCCCGT
GGAGGAAGAGGCGCGCCGCCAGCTTGCCAACACCGCGCAGTTGCCGTTCATCTTCAGCCATCTCGCGGTGATGCCCGATG
TGCATCTCGGCAAGGGCTCGACCATCGGCTCGGTGATTCCTACTGTAGGTGCCGTGATTCCGGCGGCGGTCGGCGTAGAT
ATCGGCTGCGGCATGATGGCCGTGCGTACATCGCTGCACGCATCCGACCTGCCCGATAACCTTGGCCCGCTGCGCAGCGC
CATCGAACACGCGGTGCCGCATGGGCGCACCGGGCAGGGCGGCCGGCGCGACGAAGGCGCCTGGGGAAAGATCCCGGACC
AGGTCGACAGCGTCTGGGCCGGGATGGCCCCCGACTTCCGCCGCATCACCGACAAGTATCCGCAACTCGCCCGCACCAAC
AACCGCAGCCATCTCGGCACGCTCGGCACCGGCAATCACTTCATCGAAGTCTGCCTCGACGAGGCCGATGCCGTCTGGTT
CATGCTGCATTCGGGTTCGCGCGGCGTGGGCAACGCGATCGGCACCACCTTCATCGCGCTGGCGCAGCAGGACATGCGCC
GGCACCTGGCCAACCTGCCCGACCGCGACCTCGCTTACCTGACCGAAGGGTCGGAGCACTATGACGACTATGTGTTCGCT
GTCTCATGGGCGCAGCAGTTCGCTCGGCGAAACCGCGAGCTGATGATGGCCAACGTGCTGGCTGCCGCCCAGCGCGTGAT
CCGCAAGCCGTTCACCACGCAGGCAGAGGCCGTTAACTGCCACCACAACTACGTGCAGAAGGAGCGCCACTTCGGCCAGG
ACGTGCTGGTCACGCGCAAAGGTGCCGTCAGTGCGCGCGCGGGGGAGCTGGGCATTATTCCGGGGTCGATGGGCGCGCGA
TCGTTCATCGTACGCGGCAAGGGCAACCCGGAGTCGTTCTGCTCATGCAGTCACGGCGCAGGCCGCACCATGAGCCGCAC
GGAGGCGAAGCGCCGCTTCAGCGTGGCCGACCAGGTGCGCGCGACCGAAGGCGTGGAATGCCGCAAGGACGCCGCCGTGA
TCGACGAGATCCCGATGGCCTACAAGGACATTGAAGCGGTAATGGCTGCGCAGTCAGACCTTGTGGAGATCGTGCACACG
CTCCGGCAGCTTGTGTGCGTGAAAGGCTAG

Upstream 100 bases:

>100_bases
TTAAGCGTGTTCCCTGACGCCGGATGCCGGTTTCCTCACTTCGGGATTTGACTGCGGGCCTGACCGTCTAAACTGCAGCC
GATCCGACCCGGAGACATCC

Downstream 100 bases:

>100_bases
CCGGACGACAGGCAGTGCGAAGGCGTGTGTCATTTTGTTGCATTGTGTGGCGTATTGTTGTAATTTGAGGAGAACCCCCA
CCCCTCGGATGACTCCATGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTQQARYELLKTDKGRPVKMWTRGVPVEEEARRQLANTAQLPFIFSHLAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVD
IGCGMMAVRTSLHASDLPDNLGPLRSAIEHAVPHGRTGQGGRRDEGAWGKIPDQVDSVWAGMAPDFRRITDKYPQLARTN
NRSHLGTLGTGNHFIEVCLDEADAVWFMLHSGSRGVGNAIGTTFIALAQQDMRRHLANLPDRDLAYLTEGSEHYDDYVFA
VSWAQQFARRNRELMMANVLAAAQRVIRKPFTTQAEAVNCHHNYVQKERHFGQDVLVTRKGAVSARAGELGIIPGSMGAR
SFIVRGKGNPESFCSCSHGAGRTMSRTEAKRRFSVADQVRATEGVECRKDAAVIDEIPMAYKDIEAVMAAQSDLVEIVHT
LRQLVCVKG

Sequences:

>Translated_409_residues
MTQQARYELLKTDKGRPVKMWTRGVPVEEEARRQLANTAQLPFIFSHLAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVD
IGCGMMAVRTSLHASDLPDNLGPLRSAIEHAVPHGRTGQGGRRDEGAWGKIPDQVDSVWAGMAPDFRRITDKYPQLARTN
NRSHLGTLGTGNHFIEVCLDEADAVWFMLHSGSRGVGNAIGTTFIALAQQDMRRHLANLPDRDLAYLTEGSEHYDDYVFA
VSWAQQFARRNRELMMANVLAAAQRVIRKPFTTQAEAVNCHHNYVQKERHFGQDVLVTRKGAVSARAGELGIIPGSMGAR
SFIVRGKGNPESFCSCSHGAGRTMSRTEAKRRFSVADQVRATEGVECRKDAAVIDEIPMAYKDIEAVMAAQSDLVEIVHT
LRQLVCVKG
>Mature_408_residues
TQQARYELLKTDKGRPVKMWTRGVPVEEEARRQLANTAQLPFIFSHLAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVDI
GCGMMAVRTSLHASDLPDNLGPLRSAIEHAVPHGRTGQGGRRDEGAWGKIPDQVDSVWAGMAPDFRRITDKYPQLARTNN
RSHLGTLGTGNHFIEVCLDEADAVWFMLHSGSRGVGNAIGTTFIALAQQDMRRHLANLPDRDLAYLTEGSEHYDDYVFAV
SWAQQFARRNRELMMANVLAAAQRVIRKPFTTQAEAVNCHHNYVQKERHFGQDVLVTRKGAVSARAGELGIIPGSMGARS
FIVRGKGNPESFCSCSHGAGRTMSRTEAKRRFSVADQVRATEGVECRKDAAVIDEIPMAYKDIEAVMAAQSDLVEIVHTL
RQLVCVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=449, Percent_Identity=26.7260579064588, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI2367224, Length=407, Percent_Identity=69.2874692874693, Blast_Score=600, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17506665, Length=432, Percent_Identity=28.7037037037037, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24585217, Length=435, Percent_Identity=26.6666666666667, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 44775; Mature: 44643

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQARYELLKTDKGRPVKMWTRGVPVEEEARRQLANTAQLPFIFSHLAVMPDVHLGKGS
CCCHHHHHHHHCCCCCCEEEHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAVIPAAVGVDIGCGMMAVRTSLHASDLPDNLGPLRSAIEHAVPHGRTGQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
GRRDEGAWGKIPDQVDSVWAGMAPDFRRITDKYPQLARTNNRSHLGTLGTGNHFIEVCLD
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHEECC
EADAVWFMLHSGSRGVGNAIGTTFIALAQQDMRRHLANLPDRDLAYLTEGSEHYDDYVFA
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHH
VSWAQQFARRNRELMMANVLAAAQRVIRKPFTTQAEAVNCHHNYVQKERHFGQDVLVTRK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECC
GAVSARAGELGIIPGSMGARSFIVRGKGNPESFCSCSHGAGRTMSRTEAKRRFSVADQVR
CCCCCCCCCEEECCCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ATEGVECRKDAAVIDEIPMAYKDIEAVMAAQSDLVEIVHTLRQLVCVKG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQQARYELLKTDKGRPVKMWTRGVPVEEEARRQLANTAQLPFIFSHLAVMPDVHLGKGS
CCHHHHHHHHCCCCCCEEEHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAVIPAAVGVDIGCGMMAVRTSLHASDLPDNLGPLRSAIEHAVPHGRTGQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
GRRDEGAWGKIPDQVDSVWAGMAPDFRRITDKYPQLARTNNRSHLGTLGTGNHFIEVCLD
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHEECC
EADAVWFMLHSGSRGVGNAIGTTFIALAQQDMRRHLANLPDRDLAYLTEGSEHYDDYVFA
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHH
VSWAQQFARRNRELMMANVLAAAQRVIRKPFTTQAEAVNCHHNYVQKERHFGQDVLVTRK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECC
GAVSARAGELGIIPGSMGARSFIVRGKGNPESFCSCSHGAGRTMSRTEAKRRFSVADQVR
CCCCCCCCCEEECCCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ATEGVECRKDAAVIDEIPMAYKDIEAVMAAQSDLVEIVHTLRQLVCVKG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]