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The map label for this gene is macB [H]

Identifier: 73539679

GI number: 73539679

Start: 2697021

End: 2698187

Strand: Direct

Name: macB [H]

Synonym: Reut_B5859

Alternate gene names: 73539679

Gene position: 2697021-2698187 (Clockwise)

Preceding gene: 73539678

Following gene: 73539685

Centisome position: 98.93

GC content: 65.55

Gene sequence:

>1167_bases
ATGGCGATCCCGCTCAGCTATATCGCGCGCAACCTGTGGGCCCGTCGGCTGACCACGGCGCTGACGGCGGGCGGCCTCGC
GCTGGTAGTGTTCGTGTTCGCGACCATGCTGATGCTCGACGCGGGGCTCAAGCGCACGCTGGTCACCACTGGCGAGAAAG
ACAACGTCGTCATGATCCGCAAGGGCGCGGAGACCGAAGTGCAGAGCGCGATCAGCCGCGACCAGGCCAGCATCATGGAG
ATGCACCCATCGGTCGCGATGGACGGCAACGGCCGGCCGATGGCGTCGAAAGAAGCCGTGGTGCTGATTTCGCTGAACAA
GCGCGGATCGGATACGCCGTCCAACGTGGTGATTCGCGGCGTGTCGCCAAAGGGACTGGAACTGCGGCCGCAGATCCGGA
TGGTGACGGGGCGCACGTTCCGGCCCGGTTCATCGGAGATTATCGTCGGCAGCAGCGTGGCCGGCGGCTTTACCGGTGCG
CAGCCAGGCGGGCGCCTGCGCTTCGCCCAGCGCGACTGGACCATCGTCGGCGTGTTCGATGCGGGCGGCAGCGGCTTCGA
TTCGGAGATCTGGGGCGATGCCGATCAGCTCATGCAGTCGTTCCGCCGCAGCAGCTATTCGTCGATGGTGGTACGGCTGA
CGCGGCCCGATGCGTTCGCACGGCTGCGCGCCGACATCGACGTAGATCCCCGGCTGGCCAACGAGGCCAAGCTCGAACAG
ACCTTCTACAGCGACCAGTCCAAGGCGCTGTCGACGTTCATCAACATCCTGGGCCTGACGTTGACCACGATCTTCTCGAT
TGCCGCGATGATCGGTGCCATGATCACGATGTACGCGTCGGTGGCCAACCGCGTGGCGGAGATCGGCACGTTGCGTGCGC
TGGGCTTCCGGCGCACCAACGTGCTGGCGGCGTTCCTGATCGAGGCGCTGCTGCTCGGACTCATCGGTGGCGTGGCCGGG
CTATGCTGCGCCGCGCTGATGCAGTTCGCCTCGTTCTCGACCACCAACTTCCAGACCTTCGCCGACCTGTCGTTCCGTTT
CATCCTGACACCGGGCGTCGTGGTCCGGACGTTGTTGTTCTCGATGGCGATGGGGCTGATCGGCGGCTTCCTGCCGGCAT
TGCGCGCGGCCCGCATGAACATCGTCGATGCGCTGCGGGCTCACTGA

Upstream 100 bases:

>100_bases
TGCGCGCTCGTCGTGGCGCTTTTCGCCGCGGTGGTGCCGGCGGTGCAGGCCGCACGCGTGCGCATCGTCGAAGGCCTGCG
GGCGATCGGCTAGGGATCAC

Downstream 100 bases:

>100_bases
CGCTGCCGGCCGTCAGCTCGCGGCCAGCTCTTGCCGTACAGGCGCGCGGCGTGCCAGCCCAAGCGACAGCATGGTGCCCC
CTGCCAGCAGAGCGGGGATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAIPLSYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKRTLVTTGEKDNVVMIRKGAETEVQSAISRDQASIME
MHPSVAMDGNGRPMASKEAVVLISLNKRGSDTPSNVVIRGVSPKGLELRPQIRMVTGRTFRPGSSEIIVGSSVAGGFTGA
QPGGRLRFAQRDWTIVGVFDAGGSGFDSEIWGDADQLMQSFRRSSYSSMVVRLTRPDAFARLRADIDVDPRLANEAKLEQ
TFYSDQSKALSTFINILGLTLTTIFSIAAMIGAMITMYASVANRVAEIGTLRALGFRRTNVLAAFLIEALLLGLIGGVAG
LCCAALMQFASFSTTNFQTFADLSFRFILTPGVVVRTLLFSMAMGLIGGFLPALRAARMNIVDALRAH

Sequences:

>Translated_388_residues
MAIPLSYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKRTLVTTGEKDNVVMIRKGAETEVQSAISRDQASIME
MHPSVAMDGNGRPMASKEAVVLISLNKRGSDTPSNVVIRGVSPKGLELRPQIRMVTGRTFRPGSSEIIVGSSVAGGFTGA
QPGGRLRFAQRDWTIVGVFDAGGSGFDSEIWGDADQLMQSFRRSSYSSMVVRLTRPDAFARLRADIDVDPRLANEAKLEQ
TFYSDQSKALSTFINILGLTLTTIFSIAAMIGAMITMYASVANRVAEIGTLRALGFRRTNVLAAFLIEALLLGLIGGVAG
LCCAALMQFASFSTTNFQTFADLSFRFILTPGVVVRTLLFSMAMGLIGGFLPALRAARMNIVDALRAH
>Mature_387_residues
AIPLSYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKRTLVTTGEKDNVVMIRKGAETEVQSAISRDQASIMEM
HPSVAMDGNGRPMASKEAVVLISLNKRGSDTPSNVVIRGVSPKGLELRPQIRMVTGRTFRPGSSEIIVGSSVAGGFTGAQ
PGGRLRFAQRDWTIVGVFDAGGSGFDSEIWGDADQLMQSFRRSSYSSMVVRLTRPDAFARLRADIDVDPRLANEAKLEQT
FYSDQSKALSTFINILGLTLTTIFSIAAMIGAMITMYASVANRVAEIGTLRALGFRRTNVLAAFLIEALLLGLIGGVAGL
CCAALMQFASFSTTNFQTFADLSFRFILTPGVVVRTLLFSMAMGLIGGFLPALRAARMNIVDALRAH

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=130, Percent_Identity=37.6923076923077, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41734; Mature: 41603

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPLSYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKRTLVTTGEKDNVVMIR
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEEE
KGAETEVQSAISRDQASIMEMHPSVAMDGNGRPMASKEAVVLISLNKRGSDTPSNVVIRG
CCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEC
VSPKGLELRPQIRMVTGRTFRPGSSEIIVGSSVAGGFTGAQPGGRLRFAQRDWTIVGVFD
CCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEEE
AGGSGFDSEIWGDADQLMQSFRRSSYSSMVVRLTRPDAFARLRADIDVDPRLANEAKLEQ
CCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCHHHHHH
TFYSDQSKALSTFINILGLTLTTIFSIAAMIGAMITMYASVANRVAEIGTLRALGFRRTN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAFLIEALLLGLIGGVAGLCCAALMQFASFSTTNFQTFADLSFRFILTPGVVVRTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCHHHHHHHHH
SMAMGLIGGFLPALRAARMNIVDALRAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPLSYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKRTLVTTGEKDNVVMIR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEEE
KGAETEVQSAISRDQASIMEMHPSVAMDGNGRPMASKEAVVLISLNKRGSDTPSNVVIRG
CCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEC
VSPKGLELRPQIRMVTGRTFRPGSSEIIVGSSVAGGFTGAQPGGRLRFAQRDWTIVGVFD
CCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEEE
AGGSGFDSEIWGDADQLMQSFRRSSYSSMVVRLTRPDAFARLRADIDVDPRLANEAKLEQ
CCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCHHHHHH
TFYSDQSKALSTFINILGLTLTTIFSIAAMIGAMITMYASVANRVAEIGTLRALGFRRTN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAFLIEALLLGLIGGVAGLCCAALMQFASFSTTNFQTFADLSFRFILTPGVVVRTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCHHHHHHHHH
SMAMGLIGGFLPALRAARMNIVDALRAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA