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The map label for this gene is sdsB [H]

Identifier: 73539574

GI number: 73539574

Start: 2574165

End: 2575082

Strand: Reverse

Name: sdsB [H]

Synonym: Reut_B5754

Alternate gene names: 73539574

Gene position: 2575082-2574165 (Counterclockwise)

Preceding gene: 73539579

Following gene: 73539565

Centisome position: 94.46

GC content: 66.67

Gene sequence:

>918_bases
ATGGATACGCAAAAGCTGCTGCATCTGCTCGCGGTGGTCGAGCACGGGACGTTTTCCGAGGCCGCGCGAGCGGTCCACCT
CACGCAACCGGCATTGAGCCGCAGCATCCGGTCGCTGGAAGACGAGGTGAAGGCCCCGCTATTCGACCGCGGCGCGCGGC
GTGCGCGGCTGACGGTATTTGGGGAACTGGTGGCCGAGCGTGCGCGGCGCATCCGGCTGGAGGAGCGCCAGTTGAAGCGC
GACCTGGACCTGCTGCGTGGTGGCGAGGAAGGTTCGATCACGGTCGGCATGGCGCCTGCGCCGGCCGCGCTGCTGCTCAC
GCCATTCCTGATCCACATGGCGAGCAGCCACCCGCGCATCAAGGTGCGTATCGAGACAGGCGCCACCAGTGCGCTGCTCG
ACAGGCTGCGCAACGAGTCGATCGACGCCATCGTGGGGGACGCTTACGTGTTGCGCGCCGCGGACGACATCGACATGGAT
CCGCTCGGCGACCTTCCCGCGGGCCTTGTCTGCCGCGCGGGCCATCCCATCCTGAACGAACCGATGCCCGACATCGCCAC
GATCGGCCGCTGGCCGGTGGCCACGACCACGCTAAGCGCGGTCATCAGCCGCCAGCTCGCCGATCTGTGGGGACCAGAGG
TCAACCCCGACACGTTGTTCACACTGATCTGCGACAATCTCGACATGCTACGCAGCGTGACGCTCGCCACTGACACGCTG
CTGTTCGGCGTATTGCCTATCACGCGCCATGAGCGCGCAACGGGGCAGATGGTTGAGGTGGCAATGCCTCCCGACCCCAG
CCGTTGCGGACGGTATGCAGTGGCGCGGATGGGCGCAAGGTCGCTGTCACCAGCGCTCGCCGCGCTGTATGGCTTCACGC
GCACGCACTGGCAGGAATTGTCGCAGGATCCCGCGTAA

Upstream 100 bases:

>100_bases
TCTTGGTTCTCATGTTCGATTTCTTGTTGTCTGGCCATCTTAGGGAGTCCAGAGGTATGATTCAAATGCAAATTAATAAC
GATTTCCATAACATCGACGC

Downstream 100 bases:

>100_bases
GCGGAAAAATGGACACTTTGTTTGCCAGCCGTCGCATAGCCGACCGGCGACATCAGCCGTATTATCCAGCCGGCGGGCAT
CGTAGTTGCGACGGCCAACG

Product: regulatory protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDTQKLLHLLAVVEHGTFSEAARAVHLTQPALSRSIRSLEDEVKAPLFDRGARRARLTVFGELVAERARRIRLEERQLKR
DLDLLRGGEEGSITVGMAPAPAALLLTPFLIHMASSHPRIKVRIETGATSALLDRLRNESIDAIVGDAYVLRAADDIDMD
PLGDLPAGLVCRAGHPILNEPMPDIATIGRWPVATTTLSAVISRQLADLWGPEVNPDTLFTLICDNLDMLRSVTLATDTL
LFGVLPITRHERATGQMVEVAMPPDPSRCGRYAVARMGARSLSPALAALYGFTRTHWQELSQDPA

Sequences:

>Translated_305_residues
MDTQKLLHLLAVVEHGTFSEAARAVHLTQPALSRSIRSLEDEVKAPLFDRGARRARLTVFGELVAERARRIRLEERQLKR
DLDLLRGGEEGSITVGMAPAPAALLLTPFLIHMASSHPRIKVRIETGATSALLDRLRNESIDAIVGDAYVLRAADDIDMD
PLGDLPAGLVCRAGHPILNEPMPDIATIGRWPVATTTLSAVISRQLADLWGPEVNPDTLFTLICDNLDMLRSVTLATDTL
LFGVLPITRHERATGQMVEVAMPPDPSRCGRYAVARMGARSLSPALAALYGFTRTHWQELSQDPA
>Mature_305_residues
MDTQKLLHLLAVVEHGTFSEAARAVHLTQPALSRSIRSLEDEVKAPLFDRGARRARLTVFGELVAERARRIRLEERQLKR
DLDLLRGGEEGSITVGMAPAPAALLLTPFLIHMASSHPRIKVRIETGATSALLDRLRNESIDAIVGDAYVLRAADDIDMD
PLGDLPAGLVCRAGHPILNEPMPDIATIGRWPVATTTLSAVISRQLADLWGPEVNPDTLFTLICDNLDMLRSVTLATDTL
LFGVLPITRHERATGQMVEVAMPPDPSRCGRYAVARMGARSLSPALAALYGFTRTHWQELSQDPA

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=177, Percent_Identity=31.0734463276836, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=232, Percent_Identity=25, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790399, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=205, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082024, Length=178, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87081904, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789492, Length=176, Percent_Identity=28.4090909090909, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788887, Length=271, Percent_Identity=23.9852398523985, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33354; Mature: 33354

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQKLLHLLAVVEHGTFSEAARAVHLTQPALSRSIRSLEDEVKAPLFDRGARRARLTVF
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHH
GELVAERARRIRLEERQLKRDLDLLRGGEEGSITVGMAPAPAALLLTPFLIHMASSHPRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEE
KVRIETGATSALLDRLRNESIDAIVGDAYVLRAADDIDMDPLGDLPAGLVCRAGHPILNE
EEEEECCCHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCC
PMPDIATIGRWPVATTTLSAVISRQLADLWGPEVNPDTLFTLICDNLDMLRSVTLATDTL
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LFGVLPITRHERATGQMVEVAMPPDPSRCGRYAVARMGARSLSPALAALYGFTRTHWQEL
HHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHH
SQDPA
HCCCC
>Mature Secondary Structure
MDTQKLLHLLAVVEHGTFSEAARAVHLTQPALSRSIRSLEDEVKAPLFDRGARRARLTVF
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHH
GELVAERARRIRLEERQLKRDLDLLRGGEEGSITVGMAPAPAALLLTPFLIHMASSHPRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEE
KVRIETGATSALLDRLRNESIDAIVGDAYVLRAADDIDMDPLGDLPAGLVCRAGHPILNE
EEEEECCCHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCC
PMPDIATIGRWPVATTTLSAVISRQLADLWGPEVNPDTLFTLICDNLDMLRSVTLATDTL
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LFGVLPITRHERATGQMVEVAMPPDPSRCGRYAVARMGARSLSPALAALYGFTRTHWQEL
HHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHH
SQDPA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]