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The map label for this gene is yjiA [H]

Identifier: 73539488

GI number: 73539488

Start: 2496593

End: 2497603

Strand: Reverse

Name: yjiA [H]

Synonym: Reut_B5666

Alternate gene names: 73539488

Gene position: 2497603-2496593 (Counterclockwise)

Preceding gene: 73539489

Following gene: 73539485

Centisome position: 91.62

GC content: 62.31

Gene sequence:

>1011_bases
ATGATTGAACAGTGCGAATTCACGGTGTTGTCAGGCTTCCTCGGTAGTGGCAAGACCACGCTTCTATCCACGTACCTCGC
CTGCTCCGACGTAAGCCGTGTCGCCGTCATCGTCAACGATGTCGGCGAAGTGAATATCGACGGCGCCGTCCTCGCGCTGC
AGGATGGGATTCCCATGGCAACCCTGAGCAACGGCTGCGTCTGCTGCAGCCTGACCAACGATTTGCCTTACACGATCGAT
GCATTGGTTCGCGAGCGACGCCTGTCTGGGCTGCCACCCTACACACGGATCATCCTCGAGTGCAGCGGCCTGTCCGATCC
CGGCGGGGTGATGCGCAGTCTCAGCGCACTTGCGAGCCTTGGCATGCGTGTCCGGGTAGTGACCATCTACGCATGCGACC
GGCATGTCGCACCCGAGGACTTTTCCTTGCTCGCGCAGCAGGTAAGCGCAGCGCATACGATCGTGCTGACGCGCACTGAC
CTTGTCAGTACCCAGCAAATCGTCGACGTGGCAACCGAAGCAAAGTCCCTGGGGCCGATGGGCAGGATCGTTGTGGAAAC
CGCGCCGGAGGTCCGGGCCCGCGCAGCGTTTGATGCGCCCGCGGCGCCGCCGACCAGCGACCCGGGCCATGCGCCGGGCT
GGCAGTATGAATCGCGGCATCCGCGCATCAACGTGTTCTCATTGCAATGGGATTGCGACCTGCCCTGGGACCACGTCGCC
GCGTGGCTGGAGAACCTGGCATTCTACTTCGACAGCCGCCTGCTGCGAACCAAAGGCTTAGTCAGGTTGGACAGTGGCGA
TGTATTGCTCATCCAGGGCGTCGGGCAGCATTTCGACACACCCCGGAAGCTGAACCAGCTTGCTGTGGAAGGCTCCAGCC
TTGTCGTGATCTGCAGGGATGCTTCGGTGAGCGAAATCGTCGAGCTCGCTCCCCAGATTCCTGGCATGACCGTGTCCGCG
CGCACCGCCGGCAGCAAAGCCATCAGGCTGGCTCGGCCCGGATACGACTGA

Upstream 100 bases:

>100_bases
GCTACACCATCAAGGATGGCGTGGTCTTCGACTGCGCCGAGCTCTTGAGGGATGTCGAGGATATGGTCGAGGCCTACAAG
ATGTCCGAGGCAAAGCGGCA

Downstream 100 bases:

>100_bases
TTGCCAACTCCACCGTCCATAAGGAAAGAAAGCCGGACTATGTCCGGCTTTTGTCATCTGCGTGTCGTCATTTCCCGGCA
AGGCTTTCGACAGGCTGCCA

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIEQCEFTVLSGFLGSGKTTLLSTYLACSDVSRVAVIVNDVGEVNIDGAVLALQDGIPMATLSNGCVCCSLTNDLPYTID
ALVRERRLSGLPPYTRIILECSGLSDPGGVMRSLSALASLGMRVRVVTIYACDRHVAPEDFSLLAQQVSAAHTIVLTRTD
LVSTQQIVDVATEAKSLGPMGRIVVETAPEVRARAAFDAPAAPPTSDPGHAPGWQYESRHPRINVFSLQWDCDLPWDHVA
AWLENLAFYFDSRLLRTKGLVRLDSGDVLLIQGVGQHFDTPRKLNQLAVEGSSLVVICRDASVSEIVELAPQIPGMTVSA
RTAGSKAIRLARPGYD

Sequences:

>Translated_336_residues
MIEQCEFTVLSGFLGSGKTTLLSTYLACSDVSRVAVIVNDVGEVNIDGAVLALQDGIPMATLSNGCVCCSLTNDLPYTID
ALVRERRLSGLPPYTRIILECSGLSDPGGVMRSLSALASLGMRVRVVTIYACDRHVAPEDFSLLAQQVSAAHTIVLTRTD
LVSTQQIVDVATEAKSLGPMGRIVVETAPEVRARAAFDAPAAPPTSDPGHAPGWQYESRHPRINVFSLQWDCDLPWDHVA
AWLENLAFYFDSRLLRTKGLVRLDSGDVLLIQGVGQHFDTPRKLNQLAVEGSSLVVICRDASVSEIVELAPQIPGMTVSA
RTAGSKAIRLARPGYD
>Mature_336_residues
MIEQCEFTVLSGFLGSGKTTLLSTYLACSDVSRVAVIVNDVGEVNIDGAVLALQDGIPMATLSNGCVCCSLTNDLPYTID
ALVRERRLSGLPPYTRIILECSGLSDPGGVMRSLSALASLGMRVRVVTIYACDRHVAPEDFSLLAQQVSAAHTIVLTRTD
LVSTQQIVDVATEAKSLGPMGRIVVETAPEVRARAAFDAPAAPPTSDPGHAPGWQYESRHPRINVFSLQWDCDLPWDHVA
AWLENLAFYFDSRLLRTKGLVRLDSGDVLLIQGVGQHFDTPRKLNQLAVEGSSLVVICRDASVSEIVELAPQIPGMTVSA
RTAGSKAIRLARPGYD

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=327, Percent_Identity=26.9113149847095, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI33469141, Length=303, Percent_Identity=27.0627062706271, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI126722884, Length=303, Percent_Identity=27.0627062706271, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223941779, Length=293, Percent_Identity=27.9863481228669, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI146231952, Length=327, Percent_Identity=27.217125382263, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223941776, Length=296, Percent_Identity=26.6891891891892, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI119120938, Length=307, Percent_Identity=26.3843648208469, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87082430, Length=292, Percent_Identity=30.4794520547945, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788499, Length=112, Percent_Identity=39.2857142857143, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36145; Mature: 36145

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQCEFTVLSGFLGSGKTTLLSTYLACSDVSRVAVIVNDVGEVNIDGAVLALQDGIPMA
CCCCCCCCEEHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEECCCEEEEEECCCCEE
TLSNGCVCCSLTNDLPYTIDALVRERRLSGLPPYTRIILECSGLSDPGGVMRSLSALASL
ECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHC
GMRVRVVTIYACDRHVAPEDFSLLAQQVSAAHTIVLTRTDLVSTQQIVDVATEAKSLGPM
CCEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCC
GRIVVETAPEVRARAAFDAPAAPPTSDPGHAPGWQYESRHPRINVFSLQWDCDLPWDHVA
CEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHH
AWLENLAFYFDSRLLRTKGLVRLDSGDVLLIQGVGQHFDTPRKLNQLAVEGSSLVVICRD
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCHHHHHHHEECCCEEEEEECC
ASVSEIVELAPQIPGMTVSARTAGSKAIRLARPGYD
CCHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCC
>Mature Secondary Structure
MIEQCEFTVLSGFLGSGKTTLLSTYLACSDVSRVAVIVNDVGEVNIDGAVLALQDGIPMA
CCCCCCCCEEHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEECCCEEEEEECCCCEE
TLSNGCVCCSLTNDLPYTIDALVRERRLSGLPPYTRIILECSGLSDPGGVMRSLSALASL
ECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHC
GMRVRVVTIYACDRHVAPEDFSLLAQQVSAAHTIVLTRTDLVSTQQIVDVATEAKSLGPM
CCEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCC
GRIVVETAPEVRARAAFDAPAAPPTSDPGHAPGWQYESRHPRINVFSLQWDCDLPWDHVA
CEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHH
AWLENLAFYFDSRLLRTKGLVRLDSGDVLLIQGVGQHFDTPRKLNQLAVEGSSLVVICRD
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCHHHHHHHEECCCEEEEEECC
ASVSEIVELAPQIPGMTVSARTAGSKAIRLARPGYD
CCHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]