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The map label for this gene is ttuB [H]

Identifier: 73539474

GI number: 73539474

Start: 2476730

End: 2478031

Strand: Reverse

Name: ttuB [H]

Synonym: Reut_B5652

Alternate gene names: 73539474

Gene position: 2478031-2476730 (Counterclockwise)

Preceding gene: 73539479

Following gene: 73539473

Centisome position: 90.9

GC content: 62.83

Gene sequence:

>1302_bases
GTGCAAGCGGATATCGAGAAGCGGACCTTGCGCCGCATTAGTTGGCGCATCGTGCCGTTCATCATGCTGTTGTATTTCAT
CGCCTACATCGACCGGGTCAATATCGGCTTCGCTGCCCTGACGATGAAAACGGACCTCGGCTTCACCGCCTCGATTCTCG
GCTTCGGCGCAGGCATCTTCTTCTGGGGCTATTTCCTGTTCGAGGTGCCGTCCAACATCGTGCTTCACAAGGTAGGCGCG
CGCCTGTGGATCGCCCGGGTAATGCTCACCTGGGGACTGATCTCGGCCTGCATGGCTTTCGTCCAGGGTCCGACCAGCTT
CTACATCGTTCGCTTCCTGCTTGGCGCAGCAGAGGCCGGCTTCTTCCCCGGCATCATCCTGTATCTGAGCTACTGGTTCC
CCGCGCGTCACCGGGCCGGCGTGACGGCGTTCTTTATGGCCGCTGCGCCGATCTCCACCGCGCTGGGCTCACCGCTCTCG
GCCGCGCTGCTGGAAATGCACGGCGTGATGGGCCTCGCAGGCTGGCAATGGATGTTCATCGTGGAAGCGATTCCGGCTGT
CATCCTCGGCGTCGTGGTCTTTTTCTATATGACCGATCGCCCCGAGCAGGCAACCTGGCTAAACGAGGACGAGCGTGCCT
GGCTGGTCAGGGAAATGAGCCAGGAGGCCGCCAGCAAGCGGCATCACGGTGACCACAGCGTCCTGCGCGGCCTTGCCGAC
CCCCGGGTGCTGGCCCTGGCGCTGATTTACTTTGGCACGTCGGCAGGTCTCTACACGCTGGGCATCTGGGCGCCGCAGAT
CATCAAGCAACTGGGCGTTTCGTCCATCACCGTCGGCTTTCTCAACGCCATTCCCCCGATCGTTTCGGTCATCGCCATGG
TCTTGTGGTCCCGCCATTCCGACCGCACCGGCGAACGCACGTGGCACGTAATTCTGGCCTGTGTCGCCGCCGCAGTGGGC
CTGGTGGTCGCGGCAAGCGCCAACAGCATCGTTGGACTGATTGCTGCGCTCACGCTTGTCAACGTAGGGATCAGTTGTGC
CAAGCCGCCCCTGTGGACGATGCCGACGGCGTTCCTGTCGGGCGCTGCCGCCGCGACTGGCATTGCCACCATCAATTCGA
TCGGGAACCTCGGCGGCTTTGCCGGCCCCGCCATGATTGGCTGGATCAAGGACCAGACAGGCAGCTTCGCGGGCGGACTC
TACTTCGTCGCAGGCCTGCTCGTGCTTTCCGCAGTGCTGACCCTCGTGCTGGCCACCTCGCAGAAGTCGAAGGTGACCGC
CTCCAACGCGACAGCGCACTAA

Upstream 100 bases:

>100_bases
AACGCCAAAAAAGAGTGGAAAAAGTCGCGGGCGAATAACGCAGCGAGCCGAGAAGTGGCATTTCCGCACCGATCGGGATT
CATCAACAAGGAGACACCCA

Downstream 100 bases:

>100_bases
CCACGTTGCGCCTCTCATAACCCCCGCATATCGAAAAGGAGTACCACATGGACACGGAAGCTGCAGTCCAGTCGTTGACA
GACACCATGGCGAAGTTCAC

Product: D-galactonate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQADIEKRTLRRISWRIVPFIMLLYFIAYIDRVNIGFAALTMKTDLGFTASILGFGAGIFFWGYFLFEVPSNIVLHKVGA
RLWIARVMLTWGLISACMAFVQGPTSFYIVRFLLGAAEAGFFPGIILYLSYWFPARHRAGVTAFFMAAAPISTALGSPLS
AALLEMHGVMGLAGWQWMFIVEAIPAVILGVVVFFYMTDRPEQATWLNEDERAWLVREMSQEAASKRHHGDHSVLRGLAD
PRVLALALIYFGTSAGLYTLGIWAPQIIKQLGVSSITVGFLNAIPPIVSVIAMVLWSRHSDRTGERTWHVILACVAAAVG
LVVAASANSIVGLIAALTLVNVGISCAKPPLWTMPTAFLSGAAAATGIATINSIGNLGGFAGPAMIGWIKDQTGSFAGGL
YFVAGLLVLSAVLTLVLATSQKSKVTASNATAH

Sequences:

>Translated_433_residues
MQADIEKRTLRRISWRIVPFIMLLYFIAYIDRVNIGFAALTMKTDLGFTASILGFGAGIFFWGYFLFEVPSNIVLHKVGA
RLWIARVMLTWGLISACMAFVQGPTSFYIVRFLLGAAEAGFFPGIILYLSYWFPARHRAGVTAFFMAAAPISTALGSPLS
AALLEMHGVMGLAGWQWMFIVEAIPAVILGVVVFFYMTDRPEQATWLNEDERAWLVREMSQEAASKRHHGDHSVLRGLAD
PRVLALALIYFGTSAGLYTLGIWAPQIIKQLGVSSITVGFLNAIPPIVSVIAMVLWSRHSDRTGERTWHVILACVAAAVG
LVVAASANSIVGLIAALTLVNVGISCAKPPLWTMPTAFLSGAAAATGIATINSIGNLGGFAGPAMIGWIKDQTGSFAGGL
YFVAGLLVLSAVLTLVLATSQKSKVTASNATAH
>Mature_433_residues
MQADIEKRTLRRISWRIVPFIMLLYFIAYIDRVNIGFAALTMKTDLGFTASILGFGAGIFFWGYFLFEVPSNIVLHKVGA
RLWIARVMLTWGLISACMAFVQGPTSFYIVRFLLGAAEAGFFPGIILYLSYWFPARHRAGVTAFFMAAAPISTALGSPLS
AALLEMHGVMGLAGWQWMFIVEAIPAVILGVVVFFYMTDRPEQATWLNEDERAWLVREMSQEAASKRHHGDHSVLRGLAD
PRVLALALIYFGTSAGLYTLGIWAPQIIKQLGVSSITVGFLNAIPPIVSVIAMVLWSRHSDRTGERTWHVILACVAAAVG
LVVAASANSIVGLIAALTLVNVGISCAKPPLWTMPTAFLSGAAAATGIATINSIGNLGGFAGPAMIGWIKDQTGSFAGGL
YFVAGLLVLSAVLTLVLATSQKSKVTASNATAH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=438, Percent_Identity=39.2694063926941, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI2367379, Length=399, Percent_Identity=25.8145363408521, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789152, Length=458, Percent_Identity=24.0174672489083, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=22.6757369614512, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=416, Percent_Identity=20.4326923076923, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32565914, Length=355, Percent_Identity=22.5352112676056, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=250, Percent_Identity=22.8, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=325, Percent_Identity=25.2307692307692, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322025, Length=302, Percent_Identity=27.1523178807947, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319876, Length=236, Percent_Identity=26.6949152542373, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324410, Length=159, Percent_Identity=27.0440251572327, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319250, Length=214, Percent_Identity=29.9065420560748, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=218, Percent_Identity=26.1467889908257, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=248, Percent_Identity=22.1774193548387, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639764, Length=472, Percent_Identity=22.6694915254237, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584153, Length=378, Percent_Identity=23.2804232804233, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=320, Percent_Identity=21.5625, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46530; Mature: 46530

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADIEKRTLRRISWRIVPFIMLLYFIAYIDRVNIGFAALTMKTDLGFTASILGFGAGIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHH
FWGYFLFEVPSNIVLHKVGARLWIARVMLTWGLISACMAFVQGPTSFYIVRFLLGAAEAG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
FFPGIILYLSYWFPARHRAGVTAFFMAAAPISTALGSPLSAALLEMHGVMGLAGWQWMFI
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
VEAIPAVILGVVVFFYMTDRPEQATWLNEDERAWLVREMSQEAASKRHHGDHSVLRGLAD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
PRVLALALIYFGTSAGLYTLGIWAPQIIKQLGVSSITVGFLNAIPPIVSVIAMVLWSRHS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRTGERTWHVILACVAAAVGLVVAASANSIVGLIAALTLVNVGISCAKPPLWTMPTAFLS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHC
GAAAATGIATINSIGNLGGFAGPAMIGWIKDQTGSFAGGLYFVAGLLVLSAVLTLVLATS
CHHHHHHHHHHHHHHCCCCCCCHHHHEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QKSKVTASNATAH
CCCCEECCCCCCC
>Mature Secondary Structure
MQADIEKRTLRRISWRIVPFIMLLYFIAYIDRVNIGFAALTMKTDLGFTASILGFGAGIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHH
FWGYFLFEVPSNIVLHKVGARLWIARVMLTWGLISACMAFVQGPTSFYIVRFLLGAAEAG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
FFPGIILYLSYWFPARHRAGVTAFFMAAAPISTALGSPLSAALLEMHGVMGLAGWQWMFI
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
VEAIPAVILGVVVFFYMTDRPEQATWLNEDERAWLVREMSQEAASKRHHGDHSVLRGLAD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
PRVLALALIYFGTSAGLYTLGIWAPQIIKQLGVSSITVGFLNAIPPIVSVIAMVLWSRHS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRTGERTWHVILACVAAAVGLVVAASANSIVGLIAALTLVNVGISCAKPPLWTMPTAFLS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHC
GAAAATGIATINSIGNLGGFAGPAMIGWIKDQTGSFAGGLYFVAGLLVLSAVLTLVLATS
CHHHHHHHHHHHHHHCCCCCCCHHHHEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QKSKVTASNATAH
CCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]