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The map label for this gene is tcp [H]

Identifier: 73538934

GI number: 73538934

Start: 1850000

End: 1851097

Strand: Reverse

Name: tcp [H]

Synonym: Reut_B5109

Alternate gene names: 73538934

Gene position: 1851097-1850000 (Counterclockwise)

Preceding gene: 73538935

Following gene: 73538933

Centisome position: 67.9

GC content: 67.3

Gene sequence:

>1098_bases
ATGTCGCAGGCAAATCTGAGCATCCGTGCGCGTCTGGGCGCCAGCTTCGGACTGGTCGTGCTGTTGTCGGGCGCGGCCAT
CGGCACGGGCCTGGCGCAGCTTGAGGGCAGTGACGCGGCGCGTTACACCGTGCTCGGCCTGGGCCTGGCAGCACTGGTGG
CGGCCGTGGCGGGCGCCTTGTGGCTCGCCGCGGCCATCGAGCGGCCGCTCGCGGATGCCGTCTACATCGCCGAGACCGTG
GCCGCCGGCGACCTGAGCCAGGACTTCGACACCGACCAGGGCGGTGCCTTCGGCCGGCTGCTCGGCGGCATGGGCAAGAT
GGAGGACATCCTGACCGACCTGGTAAGCCGGATCAAGAGCTCGACCGACTCGATCGCCGACTCGTCGCGTCAGATCGCGG
ATGGCAATACCGATCTCTCCCAGCGGACCGAGGAACAGGCGGCCACGCTGCAGGAAACGGCGTCTAGCATGGGCAGCCTG
ACCGATATGGTGAGGCGCAACGCCGAACGCGCCCACGCCGCCAATGACATCGCTGCCAATGCCTCTGAGATCGCCGAGCG
CGGCGGCGTGGTCGTCAATGACGTGGTGCAGACCATGCAGGCGATCAGCGCCAGCTCGAACAAGGTGGTCGAGATCATCC
AGGTTATCGAAGGCATTGCGTTCCAGACCAATATCCTGGCGCTCAATGCCGCCGTGGAAGCGGCGCGTGCGGGCGAGCAG
GGTCGTGGCTTTGCCGTGGTTGCCGGTGAAGTGCGCACACTGGCACAGCGCAGCGCCACCGCCGCGAAGGAAATTCGCGT
GCTGATCGGCGATTCCGCGCGGCAGGTCGAAGGCGGCGCCGTGCTGGTCGACAAGGCCGGGCAGACCATGGAAGAGCTCC
AGCAGGCCGTGCGCAGTGTCACGGGCATCCTCGGCGAGATCTCGGTGGCGTCGCGCGACCAGAGCAGCAGCATCGAGCAG
GTCAACCAGGCCGTGGCGCAAATGGATGCCGTCACGCAGCAGAACGCGGCACTGGTGGAACAGGCCGCAGCGGCGTCGGC
ATCGCTGGCGGACCAGGCCCATCAGCTCCAGGGCGTGGTGGGCGAGTTCAAGCTTTAA

Upstream 100 bases:

>100_bases
ACTATATTGGCTGTTCTCCCTAAATATCCGCGCGGCCGTGCCGATACTCCAACGGCAGACCATCGAAAACAGACATCGGA
CAAAAAGGGGGAGAGCAACA

Downstream 100 bases:

>100_bases
GCAGACCGCGTTTGGGGGCCCGGCATTGCACCGGCCGCCTAATCCGCAGTAACCTCTGCGCGAGGCGGCAGGCACATGCC
GCCACTTGCCCCACCTCAGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSQANLSIRARLGASFGLVVLLSGAAIGTGLAQLEGSDAARYTVLGLGLAALVAAVAGALWLAAAIERPLADAVYIAETV
AAGDLSQDFDTDQGGAFGRLLGGMGKMEDILTDLVSRIKSSTDSIADSSRQIADGNTDLSQRTEEQAATLQETASSMGSL
TDMVRRNAERAHAANDIAANASEIAERGGVVVNDVVQTMQAISASSNKVVEIIQVIEGIAFQTNILALNAAVEAARAGEQ
GRGFAVVAGEVRTLAQRSATAAKEIRVLIGDSARQVEGGAVLVDKAGQTMEELQQAVRSVTGILGEISVASRDQSSSIEQ
VNQAVAQMDAVTQQNAALVEQAAAASASLADQAHQLQGVVGEFKL

Sequences:

>Translated_365_residues
MSQANLSIRARLGASFGLVVLLSGAAIGTGLAQLEGSDAARYTVLGLGLAALVAAVAGALWLAAAIERPLADAVYIAETV
AAGDLSQDFDTDQGGAFGRLLGGMGKMEDILTDLVSRIKSSTDSIADSSRQIADGNTDLSQRTEEQAATLQETASSMGSL
TDMVRRNAERAHAANDIAANASEIAERGGVVVNDVVQTMQAISASSNKVVEIIQVIEGIAFQTNILALNAAVEAARAGEQ
GRGFAVVAGEVRTLAQRSATAAKEIRVLIGDSARQVEGGAVLVDKAGQTMEELQQAVRSVTGILGEISVASRDQSSSIEQ
VNQAVAQMDAVTQQNAALVEQAAAASASLADQAHQLQGVVGEFKL
>Mature_364_residues
SQANLSIRARLGASFGLVVLLSGAAIGTGLAQLEGSDAARYTVLGLGLAALVAAVAGALWLAAAIERPLADAVYIAETVA
AGDLSQDFDTDQGGAFGRLLGGMGKMEDILTDLVSRIKSSTDSIADSSRQIADGNTDLSQRTEEQAATLQETASSMGSLT
DMVRRNAERAHAANDIAANASEIAERGGVVVNDVVQTMQAISASSNKVVEIIQVIEGIAFQTNILALNAAVEAARAGEQG
RGFAVVAGEVRTLAQRSATAAKEIRVLIGDSARQVEGGAVLVDKAGQTMEELQQAVRSVTGILGEISVASRDQSSSIEQV
NQAVAQMDAVTQQNAALVEQAAAASASLADQAHQLQGVVGEFKL

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=53.5353535353535, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI2367378, Length=291, Percent_Identity=52.5773195876289, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1787690, Length=322, Percent_Identity=49.6894409937888, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1788194, Length=316, Percent_Identity=48.7341772151899, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1789453, Length=312, Percent_Identity=38.1410256410256, Blast_Score=191, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 37471; Mature: 37340

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQANLSIRARLGASFGLVVLLSGAAIGTGLAQLEGSDAARYTVLGLGLAALVAAVAGAL
CCCCCCEEEECCCCCCCHHHHCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
WLAAAIERPLADAVYIAETVAAGDLSQDFDTDQGGAFGRLLGGMGKMEDILTDLVSRIKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
STDSIADSSRQIADGNTDLSQRTEEQAATLQETASSMGSLTDMVRRNAERAHAANDIAAN
HHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASEIAERGGVVVNDVVQTMQAISASSNKVVEIIQVIEGIAFQTNILALNAAVEAARAGEQ
HHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
GRGFAVVAGEVRTLAQRSATAAKEIRVLIGDSARQVEGGAVLVDKAGQTMEELQQAVRSV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHH
TGILGEISVASRDQSSSIEQVNQAVAQMDAVTQQNAALVEQAAAASASLADQAHQLQGVV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEFKL
HHCCC
>Mature Secondary Structure 
SQANLSIRARLGASFGLVVLLSGAAIGTGLAQLEGSDAARYTVLGLGLAALVAAVAGAL
CCCCCEEEECCCCCCCHHHHCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
WLAAAIERPLADAVYIAETVAAGDLSQDFDTDQGGAFGRLLGGMGKMEDILTDLVSRIKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
STDSIADSSRQIADGNTDLSQRTEEQAATLQETASSMGSLTDMVRRNAERAHAANDIAAN
HHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASEIAERGGVVVNDVVQTMQAISASSNKVVEIIQVIEGIAFQTNILALNAAVEAARAGEQ
HHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
GRGFAVVAGEVRTLAQRSATAAKEIRVLIGDSARQVEGGAVLVDKAGQTMEELQQAVRSV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHH
TGILGEISVASRDQSSSIEQVNQAVAQMDAVTQQNAALVEQAAAASASLADQAHQLQGVV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEFKL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]