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The map label for this gene is mauR [H]

Identifier: 73538749

GI number: 73538749

Start: 1650248

End: 1651168

Strand: Direct

Name: mauR [H]

Synonym: Reut_B4924

Alternate gene names: 73538749

Gene position: 1650248-1651168 (Clockwise)

Preceding gene: 73538748

Following gene: 73538750

Centisome position: 60.53

GC content: 65.91

Gene sequence:

>921_bases
ATGAGAATCCGCATCGGCGAAGAGATCACCTTCCGCAAGCTCGAAGCACTGCTGGCGTTCATGGAATCCGGCAACCTGGC
CAAGGCCGCCGAGATCCTGGACACCAGTACGGTCAGCGTGCACCGCGCGTTGCACTCGCTCGAAGAGGGCACGAGCTGCG
CGCTGTTCCGGCATGAAGGCCGCAACCTGATCCCGACCGACGCGGCCCATGTGCTGGCTGACGCGGCGCGCGAGGTGCTC
AAGGCCATGGCCGACGGCATCCGCGCCACGCGCGAGGCCGCCGGTTACCTGGCGGACCATCTCAAGATCGGCTCGCTGTA
TTCGCTGACGGCGCACACCGTGCCGCAGATCGTGATCGGCCTGAAGGCGAGGCGCCCGGACCTGCAGACGGAACTGGTGC
TGGGCTCGAACGCGGACTTGCTGCAGATGCTCAAGCAGGGCTCGATCGACGCCACGCTGATGGCGACGCCCGAGCCGGAC
CCCGAGATTGAATCGATCCCGCTGTTCGAGGACGAGATATTCTTCGCCGCGCCGGCCGACTCGCCCTACGCGGCGATGCC
GGCCGTCGACCTGCGCGCCTGCCAGGACGAGCCGTTCGTGTCGCTGAGCGAGGGATTCGCCACCTCCCGCGGCTTCGCGG
AGGCGTTCAAGATTGCGGATTTCCAGCCGAACCTGGTCATGAAGGTCGGCGACATCTTCTCGCTGATGAACCTTGTCGGC
GGCGGCGTCGGCTACACACTGCTGCCGGGCCGCGTGAAGGCCGTGCATTCGCGCAATGTGGCATTCGTGCCGCTTACGTC
CGACTACGACAATATCCGGCAGACCATTGGCCTGAGCTTCCTGCGCCGGCGCGAACGCGATCCCAACCTGCTTGCGCTGG
CGGCCGTGTGCCGCATGGCGATGCGGCAAGCCGAAAAGTAA

Upstream 100 bases:

>100_bases
TATCTCCCTCATTGCCCCGGTGGTGCTCTGGTTTGTCTTTGTCGTGCTGTGACCGCCGCGCGGCTAAGATAGGGGGCCCT
CGTTTCCACCATTGCCCCCA

Downstream 100 bases:

>100_bases
GCCTCGCTTTCGCCAAGCGTAACGATCCTGCCGACCGTGTGATTGTTCCGTGCTCTCACGCTGTTTATGGTGAAGGCCAT
CAGACAGACCATAGCCGGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRIRIGEEITFRKLEALLAFMESGNLAKAAEILDTSTVSVHRALHSLEEGTSCALFRHEGRNLIPTDAAHVLADAAREVL
KAMADGIRATREAAGYLADHLKIGSLYSLTAHTVPQIVIGLKARRPDLQTELVLGSNADLLQMLKQGSIDATLMATPEPD
PEIESIPLFEDEIFFAAPADSPYAAMPAVDLRACQDEPFVSLSEGFATSRGFAEAFKIADFQPNLVMKVGDIFSLMNLVG
GGVGYTLLPGRVKAVHSRNVAFVPLTSDYDNIRQTIGLSFLRRRERDPNLLALAAVCRMAMRQAEK

Sequences:

>Translated_306_residues
MRIRIGEEITFRKLEALLAFMESGNLAKAAEILDTSTVSVHRALHSLEEGTSCALFRHEGRNLIPTDAAHVLADAAREVL
KAMADGIRATREAAGYLADHLKIGSLYSLTAHTVPQIVIGLKARRPDLQTELVLGSNADLLQMLKQGSIDATLMATPEPD
PEIESIPLFEDEIFFAAPADSPYAAMPAVDLRACQDEPFVSLSEGFATSRGFAEAFKIADFQPNLVMKVGDIFSLMNLVG
GGVGYTLLPGRVKAVHSRNVAFVPLTSDYDNIRQTIGLSFLRRRERDPNLLALAAVCRMAMRQAEK
>Mature_306_residues
MRIRIGEEITFRKLEALLAFMESGNLAKAAEILDTSTVSVHRALHSLEEGTSCALFRHEGRNLIPTDAAHVLADAAREVL
KAMADGIRATREAAGYLADHLKIGSLYSLTAHTVPQIVIGLKARRPDLQTELVLGSNADLLQMLKQGSIDATLMATPEPD
PEIESIPLFEDEIFFAAPADSPYAAMPAVDLRACQDEPFVSLSEGFATSRGFAEAFKIADFQPNLVMKVGDIFSLMNLVG
GGVGYTLLPGRVKAVHSRNVAFVPLTSDYDNIRQTIGLSFLRRRERDPNLLALAAVCRMAMRQAEK

Specific function: Transcriptional regulator of the mau genes for malonate utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=245, Percent_Identity=26.9387755102041, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788887, Length=264, Percent_Identity=26.5151515151515, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=24.5421245421245, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=22.8215767634855, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=22.8373702422145, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788297, Length=242, Percent_Identity=22.3140495867769, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33349; Mature: 33349

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRIGEEITFRKLEALLAFMESGNLAKAAEILDTSTVSVHRALHSLEEGTSCALFRHEG
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
RNLIPTDAAHVLADAAREVLKAMADGIRATREAAGYLADHLKIGSLYSLTAHTVPQIVIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKARRPDLQTELVLGSNADLLQMLKQGSIDATLMATPEPDPEIESIPLFEDEIFFAAPAD
HCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCC
SPYAAMPAVDLRACQDEPFVSLSEGFATSRGFAEAFKIADFQPNLVMKVGDIFSLMNLVG
CCCCCCCCHHHHHCCCCCCEEHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GGVGYTLLPGRVKAVHSRNVAFVPLTSDYDNIRQTIGLSFLRRRERDPNLLALAAVCRMA
CCCCEEECCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MRQAEK
HHHCCC
>Mature Secondary Structure
MRIRIGEEITFRKLEALLAFMESGNLAKAAEILDTSTVSVHRALHSLEEGTSCALFRHEG
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
RNLIPTDAAHVLADAAREVLKAMADGIRATREAAGYLADHLKIGSLYSLTAHTVPQIVIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKARRPDLQTELVLGSNADLLQMLKQGSIDATLMATPEPDPEIESIPLFEDEIFFAAPAD
HCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCC
SPYAAMPAVDLRACQDEPFVSLSEGFATSRGFAEAFKIADFQPNLVMKVGDIFSLMNLVG
CCCCCCCCHHHHHCCCCCCEEHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GGVGYTLLPGRVKAVHSRNVAFVPLTSDYDNIRQTIGLSFLRRRERDPNLLALAAVCRMA
CCCCEEECCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MRQAEK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA