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The map label for this gene is mlaA [H]

Identifier: 73538731

GI number: 73538731

Start: 1632246

End: 1633079

Strand: Direct

Name: mlaA [H]

Synonym: Reut_B4906

Alternate gene names: 73538731

Gene position: 1632246-1633079 (Clockwise)

Preceding gene: 73538730

Following gene: 73538733

Centisome position: 59.87

GC content: 66.07

Gene sequence:

>834_bases
ATGTTGCTCCCCCGAATTGCGCGCCAGCCCGCACGGCTGGCTTTCCTGGCGTTCGTTCCGCTGCTCGCGGCCGGCTGCGC
CACGGGCCCGCAGGCCAATCCCGACGACCCGCTCGAACCGATGAACCGCGTGGTCTTCAAGGTCAACGACAAACTGGACC
AGTACGTAGCCGCGCCCGTCGCCAAGGGCTACAAGGCAGTCACGCCGCAGCCCGTGCGCACCGCGGTGACCAATTTCTAT
TCGAACATTGCGGACGTAGGCAACTTCGCCAACAACCTGCTGCAAGGCAAGGGCGTGGATGCGGCCGAAAGCCTGATGCG
CGTGGCGATCAATTCGGTGCTCGGGATCGGCGGGCTGATCGACATTGCCACGCCAGCCGGCCTGCAGAAGCATTCACAGG
ACTTCGGGCTGACGCTGGGTACGTGGGGCGTGCCGTCCGGGCCCTATCTGGTGCTGCCTTTCTTCGGCCCGAGCTCGTTC
CGGGATGGCGTGGGCTTGTACGTGAATTTCCAGCTCGACCCGACCACCTATATGGATCCGGCCTGGCGCAATTCGCTGTT
TGCCATGAACGTGGTGGACGTGCGCACCAACCTGCTCGGCGCAACCGACCTGCTCTCGCTGGCGGCGCTGGACAAGTATG
CGTTCGTGCGTGACGCCTACGTGCAGCGGCGACGCTACCTGCTGGATGGCGGCAGCAGCAAGCTGCCGGACTACGGCGAC
GACGAGGAAACGGAAGGTGCCGCCATGCCATCGTCAGCGCCGGCACCGGCATCCGGACCGGCCGCGGAGCCTGCGCTGCC
TGCGGCGCCCGCCTCCGGGACACCGCAGCAATAG

Upstream 100 bases:

>100_bases
AAGCGCGCACCGGCATCCGGGGAGCGCTACGGAGTAGTCGCCCACTCGCCGTCAGGCCCTCCCCGAATAGCGATAACAAC
CTCGAATCGACCGCTGCATC

Downstream 100 bases:

>100_bases
GACTCGGCGGCCAAACACTCAGCCGCCGATGCCGAGCAGCACCACCTCGAACGTCAGCGTGGCGTTCGGCGGGATGGTGC
CCGGCACACCGCGCGCACCG

Product: VacJ-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MLLPRIARQPARLAFLAFVPLLAAGCATGPQANPDDPLEPMNRVVFKVNDKLDQYVAAPVAKGYKAVTPQPVRTAVTNFY
SNIADVGNFANNLLQGKGVDAAESLMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPFFGPSSF
RDGVGLYVNFQLDPTTYMDPAWRNSLFAMNVVDVRTNLLGATDLLSLAALDKYAFVRDAYVQRRRYLLDGGSSKLPDYGD
DEETEGAAMPSSAPAPASGPAAEPALPAAPASGTPQQ

Sequences:

>Translated_277_residues
MLLPRIARQPARLAFLAFVPLLAAGCATGPQANPDDPLEPMNRVVFKVNDKLDQYVAAPVAKGYKAVTPQPVRTAVTNFY
SNIADVGNFANNLLQGKGVDAAESLMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPFFGPSSF
RDGVGLYVNFQLDPTTYMDPAWRNSLFAMNVVDVRTNLLGATDLLSLAALDKYAFVRDAYVQRRRYLLDGGSSKLPDYGD
DEETEGAAMPSSAPAPASGPAAEPALPAAPASGTPQQ
>Mature_277_residues
MLLPRIARQPARLAFLAFVPLLAAGCATGPQANPDDPLEPMNRVVFKVNDKLDQYVAAPVAKGYKAVTPQPVRTAVTNFY
SNIADVGNFANNLLQGKGVDAAESLMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPFFGPSSF
RDGVGLYVNFQLDPTTYMDPAWRNSLFAMNVVDVRTNLLGATDLLSLAALDKYAFVRDAYVQRRRYLLDGGSSKLPDYGD
DEETEGAAMPSSAPAPASGPAAEPALPAAPASGTPQQ

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=229, Percent_Identity=34.061135371179, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 29310; Mature: 29310

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPRIARQPARLAFLAFVPLLAAGCATGPQANPDDPLEPMNRVVFKVNDKLDQYVAAPV
CCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHH
AKGYKAVTPQPVRTAVTNFYSNIADVGNFANNLLQGKGVDAAESLMRVAINSVLGIGGLI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
DIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPFFGPSSFRDGVGLYVNFQLDPTTYMDP
CCCCCCCHHHCCHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCH
AWRNSLFAMNVVDVRTNLLGATDLLSLAALDKYAFVRDAYVQRRRYLLDGGSSKLPDYGD
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEETEGAAMPSSAPAPASGPAAEPALPAAPASGTPQQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLPRIARQPARLAFLAFVPLLAAGCATGPQANPDDPLEPMNRVVFKVNDKLDQYVAAPV
CCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHH
AKGYKAVTPQPVRTAVTNFYSNIADVGNFANNLLQGKGVDAAESLMRVAINSVLGIGGLI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
DIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPFFGPSSFRDGVGLYVNFQLDPTTYMDP
CCCCCCCHHHCCHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCH
AWRNSLFAMNVVDVRTNLLGATDLLSLAALDKYAFVRDAYVQRRRYLLDGGSSKLPDYGD
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEETEGAAMPSSAPAPASGPAAEPALPAAPASGTPQQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]