| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is nirB [H]
Identifier: 73538685
GI number: 73538685
Start: 1568855
End: 1571416
Strand: Direct
Name: nirB [H]
Synonym: Reut_B4860
Alternate gene names: 73538685
Gene position: 1568855-1571416 (Clockwise)
Preceding gene: 73538684
Following gene: 73538686
Centisome position: 57.55
GC content: 64.75
Gene sequence:
>2562_bases ATGAAACTGATCATCGTCGGCCACGGCATGGTGGGTCACAAATTCCTCGAATGCCTGGCGGAAGCCGGCGCGCAGAACCT GGATGTGACCGTGCTGTGCGAAGAACCGCGCCCCGCCTACGATCGCGTGCACCTGTCCGAGTTCTTCGCCGGCAAGTCGG CCGAAGACCTTTCGCTGGTACCGGCGGGCTTCTTCGAGCAGCACAACAACATCCTGCTGCGCCTGAACGCCCGTGCAGTG TCGATCGACCGCGCCGCGCGCACGGTCACCGTATCGACCGGCGAGACGCTGGCCTATGACAAGCTGATCCTCGCCACCGG CTCCTACCCCTTCGTGCCGCCGGTGCCGGGCAAGGAGCGCAAGGACTGCTTCGTCTACCGCACCATCGAAGACCTGGAAG CGATGCGGGAGTGCGGCGCGCGCTCGAAGCGCGGCGTGGTCATCGGCGGCGGGCTGCTGGGCCTGGAGTGCGCCAAGGCG CTGCGCGACATGGACCTGGAAACGCATGTGGTCGAATTCGCGCCGCGGCTAATGGCCGTGCAGGTGGATGAAGGCGGCGG CCGCATGCTGCGCCAGAAGATCGAAGGCCTGGGCGTGACCGCCCATACCGGCAAGAACACCGTTGAAATCATCGACGGCG CGGACGGCACCCATCGCATGGTGTTTGCCGATGGCACGCACCTCGACACCGACATGATCGTGTTTTCGGCTGGCATCCGT CCGCGCGATGAACTGGCGCGTGCCGCCGGCCTTGCCGTTGGCGAACGCGGCGGCATCACGGTGGACAACAACTGCCGCAC CTCGGACCCCGATGTCTACGCGATAGGCGAGTGCGCGCTGTGGCAAGGCAAAATCTACGGCCTGGTGGCCCCGGGCTACG ACATGGCCCGTGTCGCCGCGCGTCACCTGCGCGGTGAAGCCGCCGAATTCGCCGGCGCCGACATGAGCACCAAGCTCAAG CTGATGGGCGTGGATGTCGCCAGCATCGGCGATCCGCACGGCACAGTACCGGGCGCCCGGCTCTACCAGTTCAGCGACGA CAGCAAGCAGGTCTACAAGAAGCTGGTGGTGTCCGACTGCGGCAAGTACCTGCTCGGGGGCGTGCTGATCGGCGACGCCA GCGAGTACGGCACGCTGCTGCAGATGATGCTGAACAAGATCGAGCTGCCCGAGTCGCCGGAATTCCTGATCCTGCCCGAC AGCAGCGGCAAGGCCAAGCCAGCGCTCGGCGCCGACGCGCTGCCCGACACCGCGCAGATCTGCTCGTGCAACAACGTGTC GAAGGGCGAGATCTGCGCCGCGGTGTGCGACGGCGCCACCAGCATCGGCGCGATGAAGAGCTGCACCAAGGCCGGAACTG CCTGCGGCGGCTGCGTGCCGCTGGTCACGCAGATCATGAAGGCCGAGATGAAGAAGCAGGGCATGGCCGTCAACAACCAT CTCTGCGAACACTTCCCGTACTCGCGCCAGGAACTCTATCACCTCGTGCGCGTGGGCAAGTTCAAGACCTTCGATGCGCT GCTGGAAGCGCACGGCAAGGGCCTGGGCTGCGACATCTGCAAGCCGACCGTCGGCAGCATCCTGGCCTCGTGCTGGAATG AGTTCGTGCTGAAGGAAGAGCACGCCGCGCTGCAGGACTCCAACGACTACTACCTCGCCAACATCCAGAAGGACGGCACC TACTCCGTGGTGCCTCGCATGCCGGGCGGTGAAGTCACGCCGGAAGGGCTGATCGCCGTGGGACAGGTGGCGAAGAAGTA TGGCCTGTACACCAAGATCACCGGTGGCCAGCGTGTGGACCTGTTTGGTGCACGCGCTGAGGAGTTGCCCTATATCTGGG AAGAACTGATCGCCGCGGGCTTCGAATCAGGTCATGCCTATGGCAAGGCGCTGCGCACGGTGAAGTCGTGCGTCGGTTCC ACGTGGTGCCGCTATGGCGTGGATGACTCGGTCGGCCTCGCCATCGAACTCGAGAACCGCTACAAGGGCCTGCGCGCGCC GCACAAGATCAAGTTCGGCGTATCGGGCTGCACGCGCGAATGCGCCGAGGCGCAGGGCAAGGACGTCGGTGTGATCGCCA CCGAGAAGGGCTGGAACCTCTATGTGTGCGGCAACGGCGGCATGAAGCCTCGCCACGCCGAACTGCTGGCCGGCGACCTG GACCGCGACACGCTGATCCGCTACATCGACCGCTTCCTGATGTTCTACGTGCGCACCGCCGACCGCCTGCAACGCACCAG CGTGTGGCGCGACAACCTGGAAGGCGGCCTCGACTATCTGAAGGACGTCGTGCTCGACGACAAGCTCGGCATTGCCGCCG ATCTGGAAGCCGAAATGCAGCACGTGGTCGATACCTACGAAGACGAGTGGAAGAAGGCAGTCACCGATCCCGAGACGCGC AAGCGCTTCCGCCACTTCGTCAACAGCGAACGCCGCGACGACAACCTTGTCTTCATCGAAGAGCGCGGACAGATTCGGCC GGCCACGCCGGAGGAACGGAACTTGCAACGTTCCCGCCTGAGCCACATTCCCGTAGTGGCCGTGCCCGCAAAAGCAGCCT GA
Upstream 100 bases:
>100_bases AGGCGCTGTACGACAGCGCGCTGGCCAACTGAATAGCACGCATCTCCACCACAACAGCATCCCGAGCAGCACAGACTGAC TATCGGACAAGGAACGCATC
Downstream 100 bases:
>100_bases ATTCAGGTAAACGCAACGAAAGCGAAGGAGAACGTGATGAGCCATACCCACCATCCCGAAACCTGGACTGCGATCTGCAC CTTGCGCGAGATCGTGCCCA
Product: assimilatory nitrite reductase (NAD(P)H) large subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 853; Mature: 853
Protein sequence:
>853_residues MKLIIVGHGMVGHKFLECLAEAGAQNLDVTVLCEEPRPAYDRVHLSEFFAGKSAEDLSLVPAGFFEQHNNILLRLNARAV SIDRAARTVTVSTGETLAYDKLILATGSYPFVPPVPGKERKDCFVYRTIEDLEAMRECGARSKRGVVIGGGLLGLECAKA LRDMDLETHVVEFAPRLMAVQVDEGGGRMLRQKIEGLGVTAHTGKNTVEIIDGADGTHRMVFADGTHLDTDMIVFSAGIR PRDELARAAGLAVGERGGITVDNNCRTSDPDVYAIGECALWQGKIYGLVAPGYDMARVAARHLRGEAAEFAGADMSTKLK LMGVDVASIGDPHGTVPGARLYQFSDDSKQVYKKLVVSDCGKYLLGGVLIGDASEYGTLLQMMLNKIELPESPEFLILPD SSGKAKPALGADALPDTAQICSCNNVSKGEICAAVCDGATSIGAMKSCTKAGTACGGCVPLVTQIMKAEMKKQGMAVNNH LCEHFPYSRQELYHLVRVGKFKTFDALLEAHGKGLGCDICKPTVGSILASCWNEFVLKEEHAALQDSNDYYLANIQKDGT YSVVPRMPGGEVTPEGLIAVGQVAKKYGLYTKITGGQRVDLFGARAEELPYIWEELIAAGFESGHAYGKALRTVKSCVGS TWCRYGVDDSVGLAIELENRYKGLRAPHKIKFGVSGCTRECAEAQGKDVGVIATEKGWNLYVCGNGGMKPRHAELLAGDL DRDTLIRYIDRFLMFYVRTADRLQRTSVWRDNLEGGLDYLKDVVLDDKLGIAADLEAEMQHVVDTYEDEWKKAVTDPETR KRFRHFVNSERRDDNLVFIEERGQIRPATPEERNLQRSRLSHIPVVAVPAKAA
Sequences:
>Translated_853_residues MKLIIVGHGMVGHKFLECLAEAGAQNLDVTVLCEEPRPAYDRVHLSEFFAGKSAEDLSLVPAGFFEQHNNILLRLNARAV SIDRAARTVTVSTGETLAYDKLILATGSYPFVPPVPGKERKDCFVYRTIEDLEAMRECGARSKRGVVIGGGLLGLECAKA LRDMDLETHVVEFAPRLMAVQVDEGGGRMLRQKIEGLGVTAHTGKNTVEIIDGADGTHRMVFADGTHLDTDMIVFSAGIR PRDELARAAGLAVGERGGITVDNNCRTSDPDVYAIGECALWQGKIYGLVAPGYDMARVAARHLRGEAAEFAGADMSTKLK LMGVDVASIGDPHGTVPGARLYQFSDDSKQVYKKLVVSDCGKYLLGGVLIGDASEYGTLLQMMLNKIELPESPEFLILPD SSGKAKPALGADALPDTAQICSCNNVSKGEICAAVCDGATSIGAMKSCTKAGTACGGCVPLVTQIMKAEMKKQGMAVNNH LCEHFPYSRQELYHLVRVGKFKTFDALLEAHGKGLGCDICKPTVGSILASCWNEFVLKEEHAALQDSNDYYLANIQKDGT YSVVPRMPGGEVTPEGLIAVGQVAKKYGLYTKITGGQRVDLFGARAEELPYIWEELIAAGFESGHAYGKALRTVKSCVGS TWCRYGVDDSVGLAIELENRYKGLRAPHKIKFGVSGCTRECAEAQGKDVGVIATEKGWNLYVCGNGGMKPRHAELLAGDL DRDTLIRYIDRFLMFYVRTADRLQRTSVWRDNLEGGLDYLKDVVLDDKLGIAADLEAEMQHVVDTYEDEWKKAVTDPETR KRFRHFVNSERRDDNLVFIEERGQIRPATPEERNLQRSRLSHIPVVAVPAKAA >Mature_853_residues MKLIIVGHGMVGHKFLECLAEAGAQNLDVTVLCEEPRPAYDRVHLSEFFAGKSAEDLSLVPAGFFEQHNNILLRLNARAV SIDRAARTVTVSTGETLAYDKLILATGSYPFVPPVPGKERKDCFVYRTIEDLEAMRECGARSKRGVVIGGGLLGLECAKA LRDMDLETHVVEFAPRLMAVQVDEGGGRMLRQKIEGLGVTAHTGKNTVEIIDGADGTHRMVFADGTHLDTDMIVFSAGIR PRDELARAAGLAVGERGGITVDNNCRTSDPDVYAIGECALWQGKIYGLVAPGYDMARVAARHLRGEAAEFAGADMSTKLK LMGVDVASIGDPHGTVPGARLYQFSDDSKQVYKKLVVSDCGKYLLGGVLIGDASEYGTLLQMMLNKIELPESPEFLILPD SSGKAKPALGADALPDTAQICSCNNVSKGEICAAVCDGATSIGAMKSCTKAGTACGGCVPLVTQIMKAEMKKQGMAVNNH LCEHFPYSRQELYHLVRVGKFKTFDALLEAHGKGLGCDICKPTVGSILASCWNEFVLKEEHAALQDSNDYYLANIQKDGT YSVVPRMPGGEVTPEGLIAVGQVAKKYGLYTKITGGQRVDLFGARAEELPYIWEELIAAGFESGHAYGKALRTVKSCVGS TWCRYGVDDSVGLAIELENRYKGLRAPHKIKFGVSGCTRECAEAQGKDVGVIATEKGWNLYVCGNGGMKPRHAELLAGDL DRDTLIRYIDRFLMFYVRTADRLQRTSVWRDNLEGGLDYLKDVVLDDKLGIAADLEAEMQHVVDTYEDEWKKAVTDPETR KRFRHFVNSERRDDNLVFIEERGQIRPATPEERNLQRSRLSHIPVVAVPAKAA
Specific function: Nitrate assimilation (denitrification); second step. [C]
COG id: COG1251
COG function: function code C; NAD(P)H-nitrite reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]
Homologues:
Organism=Homo sapiens, GI65787454, Length=318, Percent_Identity=29.559748427673, Blast_Score=99, Evalue=2e-20, Organism=Homo sapiens, GI226437568, Length=318, Percent_Identity=29.559748427673, Blast_Score=99, Evalue=2e-20, Organism=Homo sapiens, GI21389617, Length=318, Percent_Identity=29.559748427673, Blast_Score=99, Evalue=2e-20, Organism=Escherichia coli, GI1789765, Length=854, Percent_Identity=61.5925058548009, Blast_Score=1107, Evalue=0.0, Organism=Escherichia coli, GI1789065, Length=322, Percent_Identity=27.3291925465839, Blast_Score=124, Evalue=4e-29, Organism=Escherichia coli, GI1788892, Length=278, Percent_Identity=26.6187050359712, Blast_Score=102, Evalue=1e-22, Organism=Escherichia coli, GI87082354, Length=272, Percent_Identity=27.2058823529412, Blast_Score=78, Evalue=2e-15, Organism=Escherichia coli, GI1787352, Length=236, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559934, Length=307, Percent_Identity=27.6872964169381, Blast_Score=112, Evalue=1e-24, Organism=Drosophila melanogaster, GI24639257, Length=289, Percent_Identity=28.719723183391, Blast_Score=90, Evalue=8e-18, Organism=Drosophila melanogaster, GI281359715, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI281359713, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI24639250, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI18543267, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI24639252, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI24585130, Length=278, Percent_Identity=21.5827338129496, Blast_Score=73, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007419 - InterPro: IPR013027 - InterPro: IPR005117 - InterPro: IPR012744 - InterPro: IPR017121 - InterPro: IPR006067 - InterPro: IPR006066 - InterPro: IPR001327 [H]
Pfam domain/function: PF04324 Fer2_BFD; PF01077 NIR_SIR; PF03460 NIR_SIR_ferr; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]
EC number: =1.7.1.4 [H]
Molecular weight: Translated: 92968; Mature: 92968
Theoretical pI: Translated: 6.32; Mature: 6.32
Prosite motif: PS00022 EGF_1 ; PS00365 NIR_SIR
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.8 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 2.8 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 5.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLIIVGHGMVGHKFLECLAEAGAQNLDVTVLCEEPRPAYDRVHLSEFFAGKSAEDLSLV CEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEC PAGFFEQHNNILLRLNARAVSIDRAARTVTVSTGETLAYDKLILATGSYPFVPPVPGKER CCHHHHCCCCEEEEEECEEEEECCCCEEEEEECCCEEEECEEEEEECCCCCCCCCCCCCC KDCFVYRTIEDLEAMRECGARSKRGVVIGGGLLGLECAKALRDMDLETHVVEFAPRLMAV CCEEEEEEHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCEEEE QVDEGGGRMLRQKIEGLGVTAHTGKNTVEIIDGADGTHRMVFADGTHLDTDMIVFSAGIR EECCCCHHHHHHHHHHCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCC PRDELARAAGLAVGERGGITVDNNCRTSDPDVYAIGECALWQGKIYGLVAPGYDMARVAA CHHHHHHHHCCCCCCCCCEEECCCCCCCCCCEEEECCEEEECCEEEEEECCCCHHHHHHH RHLRGEAAEFAGADMSTKLKLMGVDVASIGDPHGTVPGARLYQFSDDSKQVYKKLVVSDC HHHCCCHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH GKYLLGGVLIGDASEYGTLLQMMLNKIELPESPEFLILPDSSGKAKPALGADALPDTAQI HHHHHCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHH CSCNNVSKGEICAAVCDGATSIGAMKSCTKAGTACGGCVPLVTQIMKAEMKKQGMAVNNH HCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH LCEHFPYSRQELYHLVRVGKFKTFDALLEAHGKGLGCDICKPTVGSILASCWNEFVLKEE HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH HAALQDSNDYYLANIQKDGTYSVVPRMPGGEVTPEGLIAVGQVAKKYGLYTKITGGQRVD HHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEE LFGARAEELPYIWEELIAAGFESGHAYGKALRTVKSCVGSTWCRYGVDDSVGLAIELENR EECCCHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEECCC YKGLRAPHKIKFGVSGCTRECAEAQGKDVGVIATEKGWNLYVCGNGGMKPRHAELLAGDL CCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHCCC DRDTLIRYIDRFLMFYVRTADRLQRTSVWRDNLEGGLDYLKDVVLDDKLGIAADLEAEMQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHH HVVDTYEDEWKKAVTDPETRKRFRHFVNSERRDDNLVFIEERGQIRPATPEERNLQRSRL HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH SHIPVVAVPAKAA CCCCEEEECCCCC >Mature Secondary Structure MKLIIVGHGMVGHKFLECLAEAGAQNLDVTVLCEEPRPAYDRVHLSEFFAGKSAEDLSLV CEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEC PAGFFEQHNNILLRLNARAVSIDRAARTVTVSTGETLAYDKLILATGSYPFVPPVPGKER CCHHHHCCCCEEEEEECEEEEECCCCEEEEEECCCEEEECEEEEEECCCCCCCCCCCCCC KDCFVYRTIEDLEAMRECGARSKRGVVIGGGLLGLECAKALRDMDLETHVVEFAPRLMAV CCEEEEEEHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCEEEE QVDEGGGRMLRQKIEGLGVTAHTGKNTVEIIDGADGTHRMVFADGTHLDTDMIVFSAGIR EECCCCHHHHHHHHHHCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCC PRDELARAAGLAVGERGGITVDNNCRTSDPDVYAIGECALWQGKIYGLVAPGYDMARVAA CHHHHHHHHCCCCCCCCCEEECCCCCCCCCCEEEECCEEEECCEEEEEECCCCHHHHHHH RHLRGEAAEFAGADMSTKLKLMGVDVASIGDPHGTVPGARLYQFSDDSKQVYKKLVVSDC HHHCCCHHHHCCCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHH GKYLLGGVLIGDASEYGTLLQMMLNKIELPESPEFLILPDSSGKAKPALGADALPDTAQI HHHHHCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHH CSCNNVSKGEICAAVCDGATSIGAMKSCTKAGTACGGCVPLVTQIMKAEMKKQGMAVNNH HCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH LCEHFPYSRQELYHLVRVGKFKTFDALLEAHGKGLGCDICKPTVGSILASCWNEFVLKEE HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH HAALQDSNDYYLANIQKDGTYSVVPRMPGGEVTPEGLIAVGQVAKKYGLYTKITGGQRVD HHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEE LFGARAEELPYIWEELIAAGFESGHAYGKALRTVKSCVGSTWCRYGVDDSVGLAIELENR EECCCHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEECCC YKGLRAPHKIKFGVSGCTRECAEAQGKDVGVIATEKGWNLYVCGNGGMKPRHAELLAGDL CCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHCCC DRDTLIRYIDRFLMFYVRTADRLQRTSVWRDNLEGGLDYLKDVVLDDKLGIAADLEAEMQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHH HVVDTYEDEWKKAVTDPETRKRFRHFVNSERRDDNLVFIEERGQIRPATPEERNLQRSRL HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH SHIPVVAVPAKAA CCCCEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2543955; 2200672; 9278503; 2445993 [H]