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The map label for this gene is 73538612

Identifier: 73538612

GI number: 73538612

Start: 1485141

End: 1486304

Strand: Reverse

Name: 73538612

Synonym: Reut_B4787

Alternate gene names: NA

Gene position: 1486304-1485141 (Counterclockwise)

Preceding gene: 73538613

Following gene: 73538611

Centisome position: 54.52

GC content: 68.38

Gene sequence:

>1164_bases
ATGACCCTGAACGGATCCGCCTATATCGTGGGGGCCTACGAGCATCCCACGCGCAAAGCCGATGACCTGTCGGTCGCGCG
CCTGCATGCCGATGTGGCGCGCGGTGCGCTGGCCGACGCCGGCCTCACCGCTGCCGATGTCGACGGCTACTTCTGTGCAG
GCGACGCGCCGGGCCTGGGGACGACCACGATCGTCGAATACCTGGGCCTGAAGCCGCGCCATGTGGATTCCACCGAATGC
GGCGGCTCCGCGCCGATCCTGCACGTTGCGCATGCGGCCGAGGCCATTGCCGCGGGGCGCTGCAATGTCGCGCTGATCAC
GCTGGCCGGAAGGCCGCGTGCGGCGGGCGCCGCGTTGGCGCTGCGGGCGCCGGACCCGGATGCGCCCGATGTGGCCTTCG
AACTGCCATTCGGCCCGGCCACGCAGAACCTGTACGGCATGGTCGCGAAACGCCATATGTACGAGTTCGGCACCACCAGC
GAACAGCTCGCATGGATCAAGGTGGCGGCGTCCCATCACGCCCAGCACAACCCGCACGCGATGCTGCGCAATGTGGTGAC
CGTCGAAGACGTCGTCAACTCGCCGATGGTGGCCGACCCGCTGCACCGGCTCGACTGCTGCGTGATGAGCGACGGTGGCG
GCGCGCTGATCGTCGCGCGACCCGAGATCGCGCGGCAGCTCAGGCGCCCGCTCGTGAAAGTGCGCGGCACCGGCGAAGCG
CCCAAGCATGCAATGGGCGGCAATATCGACCTGACCTGGTCGGCCGCTGCATGGTCGGGCCCGGCTGCGTTCGCGGAAGC
GGGCGTCACCCCAGCCGACATCAAATACGCGTCGCTGTACGACAGCTTCACGATCACCGTGCTGATGCAGCTGGAAGACC
TGGGCTTCTGCAAGAAGGGCGAGGGCGGCAAGTTCGTCGCCGACGGCGGACTGATCTCCGGCGTGGGACGCCTTCCGTTC
AACACCGATGGCGGCGGCTTGTGCAACAACCATCCGGCCAACCGCGGCGGCGTCACCAAGGTGATCGAGGCCGTGCGCCA
GCTGCGCGGCGAGGCGCATCCCGCGGTGCAGGTCAGCAATTGCGACCTGGCCCTTGCCAGCGGCATCGGCGGCGCGCTCG
CGTCCCGCCATACCGCGGCCACGCTGATTCTTGAAAGGGAATGA

Upstream 100 bases:

>100_bases
CTTGCCTACTGGGGCCCTGTCATCAAGGCCAGCGGCTTTACCCCTGACCAGTAATCCGGGCGCAACGCCAGCCATCTCCA
CCTAGTTCCTGCCTTTCATC

Downstream 100 bases:

>100_bases
CCAACATGAGCACACCTGCCACGCCTGCCAACGCCGCCGCCAAGGCGCCGCCCGCTGGCCCGCGCAAGATCCCCGCGCCG
CGCACGCTGCCGGAAAGCCA

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTLNGSAYIVGAYEHPTRKADDLSVARLHADVARGALADAGLTAADVDGYFCAGDAPGLGTTTIVEYLGLKPRHVDSTEC
GGSAPILHVAHAAEAIAAGRCNVALITLAGRPRAAGAALALRAPDPDAPDVAFELPFGPATQNLYGMVAKRHMYEFGTTS
EQLAWIKVAASHHAQHNPHAMLRNVVTVEDVVNSPMVADPLHRLDCCVMSDGGGALIVARPEIARQLRRPLVKVRGTGEA
PKHAMGGNIDLTWSAAAWSGPAAFAEAGVTPADIKYASLYDSFTITVLMQLEDLGFCKKGEGGKFVADGGLISGVGRLPF
NTDGGGLCNNHPANRGGVTKVIEAVRQLRGEAHPAVQVSNCDLALASGIGGALASRHTAATLILERE

Sequences:

>Translated_387_residues
MTLNGSAYIVGAYEHPTRKADDLSVARLHADVARGALADAGLTAADVDGYFCAGDAPGLGTTTIVEYLGLKPRHVDSTEC
GGSAPILHVAHAAEAIAAGRCNVALITLAGRPRAAGAALALRAPDPDAPDVAFELPFGPATQNLYGMVAKRHMYEFGTTS
EQLAWIKVAASHHAQHNPHAMLRNVVTVEDVVNSPMVADPLHRLDCCVMSDGGGALIVARPEIARQLRRPLVKVRGTGEA
PKHAMGGNIDLTWSAAAWSGPAAFAEAGVTPADIKYASLYDSFTITVLMQLEDLGFCKKGEGGKFVADGGLISGVGRLPF
NTDGGGLCNNHPANRGGVTKVIEAVRQLRGEAHPAVQVSNCDLALASGIGGALASRHTAATLILERE
>Mature_386_residues
TLNGSAYIVGAYEHPTRKADDLSVARLHADVARGALADAGLTAADVDGYFCAGDAPGLGTTTIVEYLGLKPRHVDSTECG
GSAPILHVAHAAEAIAAGRCNVALITLAGRPRAAGAALALRAPDPDAPDVAFELPFGPATQNLYGMVAKRHMYEFGTTSE
QLAWIKVAASHHAQHNPHAMLRNVVTVEDVVNSPMVADPLHRLDCCVMSDGGGALIVARPEIARQLRRPLVKVRGTGEAP
KHAMGGNIDLTWSAAAWSGPAAFAEAGVTPADIKYASLYDSFTITVLMQLEDLGFCKKGEGGKFVADGGLISGVGRLPFN
TDGGGLCNNHPANRGGVTKVIEAVRQLRGEAHPAVQVSNCDLALASGIGGALASRHTAATLILERE

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=372, Percent_Identity=26.8817204301075, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI302344762, Length=248, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI302344760, Length=248, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI302344767, Length=248, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI55956775, Length=205, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=355, Percent_Identity=26.1971830985915, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585051, Length=401, Percent_Identity=28.927680798005, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19921506, Length=400, Percent_Identity=28.25, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40210; Mature: 40079

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNGSAYIVGAYEHPTRKADDLSVARLHADVARGALADAGLTAADVDGYFCAGDAPGLG
CEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCC
TTTIVEYLGLKPRHVDSTECGGSAPILHVAHAAEAIAAGRCNVALITLAGRPRAAGAALA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEE
LRAPDPDAPDVAFELPFGPATQNLYGMVAKRHMYEFGTTSEQLAWIKVAASHHAQHNPHA
EECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEEEEEHHCCCCCHHH
MLRNVVTVEDVVNSPMVADPLHRLDCCVMSDGGGALIVARPEIARQLRRPLVKVRGTGEA
HHHHHHHHHHHHCCCCHHCHHHHCEEEEEECCCCEEEEECHHHHHHHHHHHEEECCCCCC
PKHAMGGNIDLTWSAAAWSGPAAFAEAGVTPADIKYASLYDSFTITVLMQLEDLGFCKKG
CCCCCCCCEEEEEECCCCCCCHHHHHCCCCHHHEEEHHHHCCEEEEEEEEEHHCCCCCCC
EGGKFVADGGLISGVGRLPFNTDGGGLCNNHPANRGGVTKVIEAVRQLRGEAHPAVQVSN
CCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECC
CDLALASGIGGALASRHTAATLILERE
CCEEEECCCCHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
TLNGSAYIVGAYEHPTRKADDLSVARLHADVARGALADAGLTAADVDGYFCAGDAPGLG
EECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCC
TTTIVEYLGLKPRHVDSTECGGSAPILHVAHAAEAIAAGRCNVALITLAGRPRAAGAALA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEE
LRAPDPDAPDVAFELPFGPATQNLYGMVAKRHMYEFGTTSEQLAWIKVAASHHAQHNPHA
EECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEEEEEHHCCCCCHHH
MLRNVVTVEDVVNSPMVADPLHRLDCCVMSDGGGALIVARPEIARQLRRPLVKVRGTGEA
HHHHHHHHHHHHCCCCHHCHHHHCEEEEEECCCCEEEEECHHHHHHHHHHHEEECCCCCC
PKHAMGGNIDLTWSAAAWSGPAAFAEAGVTPADIKYASLYDSFTITVLMQLEDLGFCKKG
CCCCCCCCEEEEEECCCCCCCHHHHHCCCCHHHEEEHHHHCCEEEEEEEEEHHCCCCCCC
EGGKFVADGGLISGVGRLPFNTDGGGLCNNHPANRGGVTKVIEAVRQLRGEAHPAVQVSN
CCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECC
CDLALASGIGGALASRHTAATLILERE
CCEEEECCCCHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]