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The map label for this gene is tauD [H]

Identifier: 73538576

GI number: 73538576

Start: 1450972

End: 1451886

Strand: Reverse

Name: tauD [H]

Synonym: Reut_B4751

Alternate gene names: 73538576

Gene position: 1451886-1450972 (Counterclockwise)

Preceding gene: 73538577

Following gene: 73538575

Centisome position: 53.26

GC content: 63.28

Gene sequence:

>915_bases
ATGACCCGTAGCAATGCCGCCGTTCAACTTAGCGATGCGTCCGCCGAACCTAACACCCTGAACTACCACGGCTTCACCAT
TACACGGTCGACGCCGACCATTGGTGCCGAGGTCGGCGGGATCGATCTGGCCGAGACGCTCGACGACGCCACCGTGGCCG
CGCTGCGGCAAGCGCTGGTGCGCCACAAGGTGCTGTTCTTCCGCGACCAGGACATCACGCCGGCACAGCACGTGCAGCTC
GCACGCCGCTTCGGCGAACTCGAAGTTCACCCCGTCTTTCCGCATCACGAGGACCATCCCGAATTGGTGCTGCTGGGCGG
AAGCAAGGACATGCGTGGCCGCGAGAACATCTACCACTCCGACGTCTCGTGGCGCGAGGTGCCGTCGATGGCGTCGATGC
TGCGCTGCGTGGAGTGCCCCGACACCGGCGGCGACACGATCTGGGTCGATATGGCACGTGCCTACGCGGCCCTGCCCGAC
GCCGTCAAGGAGCGGATCGACGGCCTCTATGCGGTTCACGACATCATGCCCGGCTTCGGCGCACGCATGACTCCGGAGGA
ACGTGAAGTCAACCGCAAGAAGTTCCCTGCGGTCACGCACCCGGTCGTGCGCACGCATCCCGAGAGCGGTGAAAAGATCC
TCTACGTCAACGAAGGATTCGTCACGCATCTCGCGAACTTCGGCGAGAAGGCGCAGTTCCGCGTGGGCTTCGATTTCCGC
TATGGCGAACTCGATCTGCTGCAGTACCTGTTCCGCCAGGCCGCCGTGCCCGAGTACCAGGTCCGCCTGAAATGGCGGCC
CAACACCATTGCGTTCTGGGATAACCGTTCCACGCAGCACTACGCCGTGCAGGACTATTTCCCCGCAGTACGCCGGATGA
TGCGCGCGACCATCATCGGCGATAAACCTTTCTGA

Upstream 100 bases:

>100_bases
GGACATCCGCCTGGACTGATTGCGCCAGCATGCAGTGAATCGCTGGTGCGGCAGATCGAGCCCGCGCCGGCCAGCAGCCC
ACCGAACAAAAGGAGATGAT

Downstream 100 bases:

>100_bases
AGCGCCCCCACTTTCAGGAGTTAACGCTCGATGCACAATCTCAATACGTTCTATATCGGGGGCGAGTGGGTTAAACCCGC
TGATGGCGCCACGTTGGCGG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTRSNAAVQLSDASAEPNTLNYHGFTITRSTPTIGAEVGGIDLAETLDDATVAALRQALVRHKVLFFRDQDITPAQHVQL
ARRFGELEVHPVFPHHEDHPELVLLGGSKDMRGRENIYHSDVSWREVPSMASMLRCVECPDTGGDTIWVDMARAYAALPD
AVKERIDGLYAVHDIMPGFGARMTPEEREVNRKKFPAVTHPVVRTHPESGEKILYVNEGFVTHLANFGEKAQFRVGFDFR
YGELDLLQYLFRQAAVPEYQVRLKWRPNTIAFWDNRSTQHYAVQDYFPAVRRMMRATIIGDKPF

Sequences:

>Translated_304_residues
MTRSNAAVQLSDASAEPNTLNYHGFTITRSTPTIGAEVGGIDLAETLDDATVAALRQALVRHKVLFFRDQDITPAQHVQL
ARRFGELEVHPVFPHHEDHPELVLLGGSKDMRGRENIYHSDVSWREVPSMASMLRCVECPDTGGDTIWVDMARAYAALPD
AVKERIDGLYAVHDIMPGFGARMTPEEREVNRKKFPAVTHPVVRTHPESGEKILYVNEGFVTHLANFGEKAQFRVGFDFR
YGELDLLQYLFRQAAVPEYQVRLKWRPNTIAFWDNRSTQHYAVQDYFPAVRRMMRATIIGDKPF
>Mature_303_residues
TRSNAAVQLSDASAEPNTLNYHGFTITRSTPTIGAEVGGIDLAETLDDATVAALRQALVRHKVLFFRDQDITPAQHVQLA
RRFGELEVHPVFPHHEDHPELVLLGGSKDMRGRENIYHSDVSWREVPSMASMLRCVECPDTGGDTIWVDMARAYAALPDA
VKERIDGLYAVHDIMPGFGARMTPEEREVNRKKFPAVTHPVVRTHPESGEKILYVNEGFVTHLANFGEKAQFRVGFDFRY
GELDLLQYLFRQAAVPEYQVRLKWRPNTIAFWDNRSTQHYAVQDYFPAVRRMMRATIIGDKPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=286, Percent_Identity=44.4055944055944, Blast_Score=236, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322971, Length=297, Percent_Identity=27.6094276094276, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 34551; Mature: 34419

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSNAAVQLSDASAEPNTLNYHGFTITRSTPTIGAEVGGIDLAETLDDATVAALRQALV
CCCCCCEEEEECCCCCCCEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RHKVLFFRDQDITPAQHVQLARRFGELEVHPVFPHHEDHPELVLLGGSKDMRGRENIYHS
HHHEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCC
DVSWREVPSMASMLRCVECPDTGGDTIWVDMARAYAALPDAVKERIDGLYAVHDIMPGFG
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCHHHHHHHHCCHHHHHHHCCCCC
ARMTPEEREVNRKKFPAVTHPVVRTHPESGEKILYVNEGFVTHLANFGEKAQFRVGFDFR
CCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEEC
YGELDLLQYLFRQAAVPEYQVRLKWRPNTIAFWDNRSTQHYAVQDYFPAVRRMMRATIIG
CCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCC
DKPF
CCCC
>Mature Secondary Structure 
TRSNAAVQLSDASAEPNTLNYHGFTITRSTPTIGAEVGGIDLAETLDDATVAALRQALV
CCCCCEEEEECCCCCCCEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RHKVLFFRDQDITPAQHVQLARRFGELEVHPVFPHHEDHPELVLLGGSKDMRGRENIYHS
HHHEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCC
DVSWREVPSMASMLRCVECPDTGGDTIWVDMARAYAALPDAVKERIDGLYAVHDIMPGFG
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCHHHHHHHHCCHHHHHHHCCCCC
ARMTPEEREVNRKKFPAVTHPVVRTHPESGEKILYVNEGFVTHLANFGEKAQFRVGFDFR
CCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEEC
YGELDLLQYLFRQAAVPEYQVRLKWRPNTIAFWDNRSTQHYAVQDYFPAVRRMMRATIIG
CCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCC
DKPF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]